DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Atpalpha and ACA2

DIOPT Version :9

Sequence 1:	NP_732572.1	Gene:	Atpalpha / 48971	FlyBaseID:	FBgn0002921	Length:	1041	Species:	Drosophila melanogaster
Sequence 2:	NP_195479.1	Gene:	ACA2 / 829918	AraportID:	AT4G37640	Length:	1014	Species:	Arabidopsis thaliana

Alignment Length:	910	Identity:	277/910 - (30%)
Similarity:	423/910 - (46%)	Gaps:	161/910 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 DLKQELDIDFHKISPEELYQRFQTHPENGLS--HAKAKENLERDGPNALTPPKQTPEWVKFCKNL 114
            |:|:   :.||. ..:.|..:.:..|.:|||  .|:..:..|..|.|            ||.::.
plant   109 DVKK---LKFHG-GVDGLAGKLKASPTDGLSTEAAQLSQRQELFGIN------------KFAESE 157

  Fly   115 FGGFAMLLW---------IGAILCFVAYSIQASTSEEPADDNLYLGIVLS--AVVIVTGIFSYYQ 168
            ..||.:.:|         |..:..||:..:..:|...|...:..|||..|  .||.||....|.|
plant   158 MRGFWVFVWEALQDMTLMILGVCAFVSLIVGIATEGWPKGSHDGLGIAASILLVVFVTATSDYRQ 222

  Fly   169 ESKSSKIMESFKNMVPQFATVIREGEKLTLRAEDLVLGDVVEVKFGDRIPADIRIIEARNFKVDN 233
            ..:...:.:..|.:..|   |.|.|.:..|...||:.||:|.:..||::|||...:...:..:|.
plant   223 SLQFRDLDKEKKKITVQ---VTRNGFRQKLSIYDLLPGDIVHLAIGDQVPADGLFLSGFSVVIDE 284

  Fly   234 SSLTGESEPQSRGAEFTHENPLETKNLAFFSTNAVEGTAKGVVISCGDHTVMGRI-AGLASGLDT 297
            |||||||||....|    :||     .....|...:|:.|.::.:.|..|..|:: |.|..|.|
plant   285 SSLTGESEPVMVNA----QNP-----FLMSGTKVQDGSCKMMITTVGMRTQWGKLMATLTEGGD- 339

  Fly   298 GETPIAKEIHHFIHLITGVAVFLGVTFFVI--------AFILGYHW----------LDAVIFLIG 344
            .|||:..:::....:|..:.:|..|..|.:        ....|.||          |:.....:.
plant   340 DETPLQVKLNGVATIIGKIGLFFAVVTFAVLVQGMFMRKLSTGTHWVWSGDEALELLEYFAIAVT 404

  Fly   345 IIVANVPEGLLATVTVCLTLTAKRMASKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHM 409
            |:|..|||||...||:.|....|:|.:...||::|.|.||:||.:|||||||||||.|.|||...
plant   405 IVVVAVPEGLPLAVTLSLAFAMKKMMNDKALVRHLAACETMGSATTICSDKTGTLTTNHMTVVKS 469

  Fly   410 WFDNQIIEADTTEDQSGVQYDRTSPGFKALSRIATLCNRAEFKGGQ-----DGVPILKKEVSGDA 469
            .....:  .|.....|.:|.:......|.|  |.::.|..   ||:     .|    |.|:.|..
plant   470 CICMNV--QDVANKGSSLQSEIPESAVKLL--IQSIFNNT---GGEVVVNKHG----KTELLGTP 523

  Fly   470 SEAALLKCMELALGDVMNIRKRNKKIAEV-PFNSTNKYQVSIHETEDTNDPRYLLVMKGAPERIL 533
            :|.|:|: :.|:||......:::.|:.:| |||||.|....:.|..:..  |.....|||.|.:|
plant   524 TETAILE-LGLSLGGKFQEERKSYKVIKVEPFNSTKKRMGVVIELPEGG--RMRAHTKGASEIVL 585

  Fly   534 ERCSTIFINGKEKV-LDEE------------MKEAFNN---AYMELGGLGERVLGFCDFMLPSDK 582
            ..|..:..:..|.| ||||            ..||...   |||::.|      ||.    |.|.
plant   586 AACDKVVNSSGEVVPLDEESIKYLNVTINEFANEALRTLCLAYMDIEG------GFS----PDDA 640

  Fly   583 YP-NGFKFNTDDINFPIDNLRFVGLMSMIDPPRAAVPDAVAKCRSAGIKVIMVTGDHPITAKAIA 646
            .| :||              ..||::.:.||.|..|.::|..||.|||.|.|||||:..||||||
plant   641 IPASGF--------------TCVGIVGIKDPVRPGVKESVELCRRAGITVRMVTGDNINTAKAIA 691

  Fly   647 KSVGIISEGNETVEDIAQRLNIPVSEVNPREAKAAVVHGAELRDVSSDQLDEILRYHTEI-VFAR 710
            :..||:::....:|                        |...|:.:.::|.|::   .:| |.||
plant   692 RECGILTDDGIAIE------------------------GPVFREKNQEELLELI---PKIQVMAR 729

  Fly   711 TSPQQKLIIVEGCQ-RMGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFA 774
            :||..|..:|:..: ....:|||||||.||:|||.:||||:||||||::|:|::||:|:|||||:
plant   730 SSPMDKHTLVKQLRTTFDEVVAVTGDGTNDAPALHEADIGLAMGIAGTEVAKESADVIILDDNFS 794

  Fly   775 SIVTGVEEGRLIFDNLKKSIAYTLTSNIPEISPFLAFILCDIPLPLGTVTILCIDLGTDMVPAIS 839
            :|||..:.||.::.|::|.:.:.||.|:..:....:........||..|.:|.:::..|.:.|::
plant   795 TIVTVAKWGRSVYINIQKFVQFQLTVNVVALVVNFSSACLTGSAPLTAVQLLWVNMIMDTLGALA 859

  Fly   840 LAYEHAEADIMKRPPRDPFNDKLVNSRLISMAYGQIGMIQAAAGFFVYFVIMAENGFLPKKLFGI 904
            ||.|....::|||.|.....:.:.|    :|....:|  ||...|.|.:::.|:.    |.:||:
plant   860 LATEPPNDELMKRLPVGRRGNFITN----AMWRNILG--QAVYQFIVIWILQAKG----KAMFGL 914

Fly 905 904
plant 915 914

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Atpalpha	NP_732572.1	ATPase-IIC_X-K	45..1041	CDD:273445	277/910 (30%)
		Cation_ATPase_N	58..132	CDD:214842	18/84 (21%)
		E1-E2_ATPase	152..383	CDD:278548	74/251 (29%)
		Cation_ATPase	445..539	CDD:289987	29/99 (29%)
		COG4087	<695..770	CDD:226572	37/76 (49%)
		Cation_ATPase_C	817..1025	CDD:279079	24/88 (27%)
ACA2	NP_195479.1	CaATP_NAI	5..49	CDD:403644
ACA2	NP_195479.1	ATPase-IIB_Ca	99..1014	CDD:273668	277/910 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53587
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920