DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Atpalpha and AT3G22910

DIOPT Version :9

Sequence 1:	NP_732572.1	Gene:	Atpalpha / 48971	FlyBaseID:	FBgn0002921	Length:	1041	Species:	Drosophila melanogaster
Sequence 2:	NP_188931.1	Gene:	AT3G22910 / 821863	AraportID:	AT3G22910	Length:	1017	Species:	Arabidopsis thaliana

Alignment Length:	1083	Identity:	298/1083 - (27%)
Similarity:	465/1083 - (42%)	Gaps:	260/1083 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 LDIDFH------KISPEELYQRFQTHPENGLSHAKAKENLER-DGPNAL---------------- 98
            :|:|.|      ||..|.|         |.|...|.:|.||. .|||.|
plant    70 IDLDHHHGDDHFKIDTETL---------NDLVKNKNQEKLESLGGPNGLVSALKSNTRLGINEEG 125

  Fly    99 -------------TPPKQTPEWV-KFCKNLFGGFAMLLWIGAILCFVAYSIQASTSEEPADDNLY 149
                         |..:|..:.: .|....|....:|:.:|.....:.:.|:....:|...|...
plant   126 DEIQRRRSTFGSNTYTRQPSKGLFHFVVEAFKDLTILILLGCATLSLGFGIKEHGLKEGWYDGGS 190

  Fly   150 LGIVLSAVVIVTGIFSYYQE---SKSSKIMESFKNMVPQFATVIREGEKLTLRAEDLVLGDVVEV 211
            :.:.:..||.|:.:.::.|.   .|.||:..:.|      ..|:|.|.:..:...|:|:||:|.:
plant   191 IFVAVFLVVAVSAVSNFRQNRQFDKLSKVSSNIK------IDVVRNGRRQEISIFDIVVGDIVCL 249

  Fly   212 KFGDRIPADIRIIEARNFKVDNSSLTGESEPQSRGAEFTHENPLETKNLAFFS-TNAVEGTAKGV 275
            ..||::|||...:|.....||.||:||||:         |.....|.|...|| |...:|..|..
plant   250 NIGDQVPADGVFVEGHLLHVDESSMTGESD---------HVEVSLTGNTFLFSGTKIADGFGKMA 305

  Fly   276 VISCGDHTVMGRIAGLASGLDTGE-TPIAKEIHHFIHLITGVAVFLGVTFFVIAFILGYHW---- 335
            |.|.|.:|..|::....| .||.| ||:...:......|..|.:.  |.|.|:..:|..::
plant   306 VTSVGMNTAWGQMMSHIS-RDTNEQTPLQSRLDKLTSSIGKVGLL--VAFLVLLVLLIRYFTGTT 367

  Fly   336 -------------------LDAVIFLIG----IIVANVPEGLLATVTVCLTLTAKRMASKNCLVK 377
                               ::||:.::.    |||..:||||...||:.|..:.|||...|.:|:
plant   368 KDESGNREYNGKTTKSDEIVNAVVKMVAAAVTIIVVAIPEGLPLAVTLTLAYSMKRMMKDNAMVR 432

  Fly   378 NLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIIEADTTEDQ------SGVQYDRTSPGF 436
            .|.|.||:||.:.||:|||||||.|:|.|...||..:..:|.:...:      .||..:.|...|
plant   433 KLSACETMGSATVICTDKTGTLTLNQMKVTDFWFGLESGKASSVSQRVVELFHQGVAMNTTGSVF 497

  Fly   437 KALSRIATLCNRAEFKGGQDGVPILKKEVSGDASEAALLK--CMELALG--------DVMNIRKR 491
            ||             |.|.:      .|.||..:|.|:|.  ..||.:|        ||:::.
plant   498 KA-------------KAGTE------YEFSGSPTEKAILSWAVEELEMGMEKVIEEHDVVHVE-- 541

  Fly   492 NKKIAEVPFNSTNKYQVSIHETEDTNDPRYLLVMKGAPERILERCSTIFINGKEKVLDEEMKE-- 554
                   .|||..|....:.:.:..|....::..|||.|:||..||| |.:|...|  .||||
plant   542 -------GFNSEKKRSGVLMKKKGVNTENNVVHWKGAAEKILAMCST-FCDGSGVV--REMKEDD 596

  Fly   555 --AFNNAYMELGGLGERVLGFCDFMLPSDKYPNGFKFNTDDINFPIDNLRFVGLMSMIDPPRAAV 617
              .|......:.....|.:.|.        |...   |.|:.....:.|..:|::.:.||.|..|
plant   597 KIQFEKIIQSMAAKSLRCIAFA--------YSED---NEDNKKLKEEKLSLLGIIGIKDPCRPGV 650

  Fly   618 PDAVAKCRSAGIKVIMVTGDHPITAKAIAKSVGIISEGNETVEDIAQRLNIPVSEVNPREAKAAV 682
            ..||..|:.||:.:.|:|||:..||:|||...||::               |..|:|    ..||
plant   651 KKAVEDCQFAGVNIKMITGDNIFTARAIAVECGILT---------------PEDEMN----SEAV 696

  Fly   683 VHGAELRDVSSDQ-LDEILRYHTEIVFARTSPQQKLIIVEGCQRMGAIVAVTGDGVNDSPALKKA 746
            :.|.:.|:.:.:: |:::.|..   |.||:||..||::|:..:.:|.:|||||||.||:||||:|
plant   697 LEGEKFRNYTQEERLEKVERIK---VMARSSPFDKLLMVKCLKELGHVVAVTGDGTNDAPALKEA 758

  Fly   747 DIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPE-ISPFLA 810
            |||::|||.|::|:|:::|:::|||||||:.|.::.||.:::|::|.|.:.||.|:.. :..|:|
plant   759 DIGLSMGIQGTEVAKESSDIVILDDNFASVATVLKWGRCVYNNIQKFIQFQLTVNVAALVINFVA 823

  Fly   811 FILC-DIPLPLGTVTILCIDLGTDMVPAISLAYEHAEADIMKRPPRD---PFNDKLVNSRLISMA 871
            .:.. |:||.  .|.:|.::|..|.:.|::||.|....|:||:.|..   |....::...|::.|
plant   824 AVSAGDVPLT--AVQLLWVNLIMDTLGALALATEKPTNDLMKKKPIGRVAPLITNIMWRNLLAQA 886

  Fly   872 YGQIGMIQAAAGFFVYFVIMAENGFLPKKLFGIRKMWDSKAVNDLTDS------YGQEWTYR--D 928
            :.||.         |..|:.    |..:.:|.:.:    |..|.|..:      ...|:..|  :
plant   887 FYQIS---------VLLVLQ----FRGRSIFNVTE----KVKNTLIFNTFVLCQVFNEFNARSLE 934

  Fly   929 RKTLEYTCH-TAFFISIVVVQWADLIICKTRRNSIFQQGMRNWALNFGLVFETVLAAFLSYCPGM 992
            :|.:....| ...||.|:||.                           :|.:.|:..||......
plant   935 KKNVFKGLHKNRLFIGIIVVT---------------------------VVLQVVMVEFLKRFADT 972

  Fly   993 EKGLRMYPLKLVWWFPAIPFALAIFIYDETRRFYLRRNPGGWL 1035
            |:      |.|..|...|..|.|.:             |.|||
plant   973 ER------LNLGQWGVCIAIAAASW-------------PIGWL 996

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Atpalpha	NP_732572.1	ATPase-IIC_X-K	45..1041	CDD:273445	298/1083 (28%)
		Cation_ATPase_N	58..132	CDD:214842	23/110 (21%)
		E1-E2_ATPase	152..383	CDD:278548	74/262 (28%)
		Cation_ATPase	445..539	CDD:289987	26/103 (25%)
		COG4087	<695..770	CDD:226572	35/75 (47%)
		Cation_ATPase_C	817..1025	CDD:279079	46/219 (21%)
AT3G22910	NP_188931.1	HAD_like	128..878	CDD:389748	246/833 (30%)
AT3G22910	NP_188931.1	Cation_ATPase_C	830..998	CDD:376368	50/232 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53587
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920