back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Atpalpha and ACA4

DIOPT Version :9

Sequence 1:	NP_732572.1	Gene:	Atpalpha / 48971	FlyBaseID:	FBgn0002921	Length:	1041	Species:	Drosophila melanogaster
Sequence 2:	NP_181687.1	Gene:	ACA4 / 818754	AraportID:	AT2G41560	Length:	1030	Species:	Arabidopsis thaliana

Alignment Length:	1065	Identity:	304/1065 - (28%)
Similarity:	479/1065 - (44%)	Gaps:	222/1065 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 SDYE---HGRADSYRVATVI---ATDDDNRTADGQYKSRRKMPAKVNKKENLDDLKQELDIDFHK 63
            :|||   |...:..|||..:   |....:..|..:||                 |..|:......
plant    47 ADYENKKHQIQEKIRVAFFVQKAALHFIDAAARPEYK-----------------LTDEVKKAGFS 94

  Fly    64 ISPEELYQRFQTHPENGLSHAKAKENLERDGPNALTPPKQTPEWVKFCKNLFG----------GF 118
            |..:||....:.:....|:.....|.|.:....:|:...::.| |...:.:||          .|
plant    95 IEADELASMVRKNDTKSLAQKGGVEELAKKVSVSLSEGIRSSE-VPIREKIFGENRYTEKPARSF 158

  Fly   119 AMLLW--------IGAILCFVAYSIQASTSEEPADDNLY--LGIVLS--AVVIVTGIFSYYQESK 171
            .|.:|        |..::|.|. ||....:.|.....:|  .||:||  .||:||.|..|.|..:
plant   159 LMFVWEALHDITLIILMVCAVV-SIGVGVATEGFPRGMYDGTGILLSILLVVMVTAISDYKQSLQ 222

  Fly   172 SSKIMESFKNMVPQFATVIREGEKLTLRAEDLVLGDVVEVKFGDRIPADIRIIEARNFKVDNSSL 236
            ...:....|.::.|   |.|:|.:..:...|||:||||.:..||::|||...|...|.::|.|||
plant   223 FRDLDREKKKIIVQ---VTRDGSRQEISIHDLVVGDVVHLSIGDQVPADGIFISGYNLEIDESSL 284

  Fly   237 TGESEPQSRGAEFTHENPLETKNLAFFSTNAVEGTAKGVVISCGDHTVMGRIAGLASGLDTG--E 299
            :|||||       :|.|  :.|......|....|:||.:|.:.|..|..|::  :.:.:|.|  |
plant   285 SGESEP-------SHVN--KEKPFLLSGTKVQNGSAKMLVTTVGMRTEWGKL--METLVDGGEDE 338

  Fly   300 TPIAKEIHHFIHLITGVAVFLG--------VTFFV--IAFILG-------YHW--------LDAV 339
            ||:..:::       |||..:|        :||.|  |.|:|.       .:|        ||..
plant   339 TPLQVKLN-------GVATIIGKIGLSFAVLTFVVLCIRFVLDKATSGSFTNWSSEDALTLLDYF 396

  Fly   340 IFLIGIIVANVPEGLLATVTVCLTLTAKRMASKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRM 404
            ...:.|||..|||||...||:.|....|::.|...||::|.|.||:||::.||:|||||||.|.|
plant   397 AISVTIIVVAVPEGLPLAVTLSLAFAMKKLMSDRALVRHLAACETMGSSTCICTDKTGTLTTNHM 461

  Fly   405 TVAHMWFDNQIIEADTTEDQSGVQYDRTSPGFKALSRIATLCNRAEFKGGQDGVPILK-----KE 464
            .|..:|..:::     .|.|.|   .:.|...:....:.:...:..|:  ..|..::|     .:
plant   462 VVNKVWICDKV-----QERQEG---SKESFELELSEEVQSTLLQGIFQ--NTGSEVVKDKDGNTQ 516

  Fly   465 VSGDASEAALLKCMELALGDVMNIRKRNKKIAEV-PFNSTNKYQVSIHETEDTNDPRYLLVM--- 525
            :.|..:|.|:|: ..|.||...|.:::..||.:: |||| :|.::|:           |:.:
plant   517 ILGSPTERAILE-FGLLLGGDFNTQRKEHKILKIEPFNS-DKKKMSV-----------LIALPGG 568

  Fly   526 ------KGAPERILERCSTIF-INGKEKVLDEEMKEAFNNAYMELGGLGERVLGFCDFMLPSDKY 583
                  |||.|.:|:.|..:. .||:...|.||...:.::...  |...|.:...|......|:.
plant   569 GARAFCKGASEIVLKMCENVVDSNGESVPLTEERITSISDIIE--GFASEALRTLCLVYKDLDEA 631

  Fly   584 PNGFKFNTDDINFPIDNLRFVGLMSMIDPPRAAVPDAVAKCRSAGIKVIMVTGDHPITAKAIAKS 648
            |:|        ..|......|.::.:.||.|..|.:||..|::|||.|.|||||:..|||||||.
plant   632 PSG--------ELPDGGYTMVAVVGIKDPVRPGVREAVQTCQAAGITVRMVTGDNISTAKAIAKE 688

  Fly   649 VGIISEGNETVEDIAQRLNIPVSEVNPREAKAAVVHGAELRDVSSDQLDEILRYHTEI-VFARTS 712
            .||.:||...:|                        |:|.||:|..::..|:   .:| |.||:.
plant   689 CGIYTEGGLAIE------------------------GSEFRDLSPHEMRAII---PKIQVMARSL 726

  Fly   713 PQQKLIIVEGCQRMGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIV 777
            |..|..:|...:::|.:|||||||.||:|||.:||||:||||||::|:|:.||:|::||||.:||
plant   727 PLDKHTLVSNLRKIGEVVAVTGDGTNDAPALHEADIGLAMGIAGTEVAKENADVIIMDDNFKTIV 791

  Fly   778 TGVEEGRLIFDNLKKSIAYTLTSNIPEISPFLAFILCDI--PLPLGTVTILCIDLGTDMVPAISL 840
            .....||.::.|::|.:.:.||.|:  ::..:.|:...|  ..||..|.:|.:::..|.:.|::|
plant   792 NVARWGRAVYINIQKFVQFQLTVNV--VALIINFVSACITGSAPLTAVQLLWVNMIMDTLGALAL 854

  Fly   841 AYEHAEADIMKRPPRDPFNDKLVNSRLISMAYGQI--GMIQAAAGFFVY-FVIMAENGFLPKKLF 902
            |.|.....:|||.|             |:.....|  .|.:..||..|| .:::....|..|.|.
plant   855 ATEPPNEGLMKRAP-------------IARTASFITKTMWRNIAGQSVYQLIVLGILNFAGKSLL 906

  Fly   903 GIRKMWDSKAVNDLTDSYGQEWTYRDRKTLEYTCHTAFFISIVVVQ-WADLIICKTRRNSIFQQG 966
            .:... ||.||                      .:|..|.|.|..| :.::...:..:.::| :|
plant   907 KLDGP-DSTAV----------------------LNTVIFNSFVFCQVFNEINSREIEKINVF-KG 947

  Fly   967 MRN-----WALNFGLVFETVLAAFL 986
            |.|     |.:...:||:.::..||
plant   948 MFNSWVFTWVMTVTVVFQVIIVEFL 972

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.