DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Atpalpha and atp2b4

DIOPT Version :9

Sequence 1:	NP_732572.1	Gene:	Atpalpha / 48971	FlyBaseID:	FBgn0002921	Length:	1041	Species:	Drosophila melanogaster
Sequence 2:	NP_001070935.1	Gene:	atp2b4 / 768304	ZFINID:	ZDB-GENE-061027-60	Length:	316	Species:	Danio rerio

Alignment Length:	273	Identity:	71/273 - (26%)
Similarity:	122/273 - (44%)	Gaps:	57/273 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 QRFQTHPENGLSHAKAKENLERD----GPNALTPPKQTPEWVKFCKNLFGGFAMLLW-----IGA 126
            :|.:|.|..|||...|  ::|:.    |.|.: |||:...           |..|:|     :..
Zfish    57 RRLKTSPIEGLSGNPA--DIEKRHTSFGKNFI-PPKKPKT-----------FLQLVWEALQDVTL 107

  Fly   127 ILCFVA--YSIQASTSEEPADDNLYLG--------------------IVLSAVVIV-TGIFSYYQ 168
            |:..||  .|:..|....|..||...|                    |:.|.:::| ...|:.:.
Zfish   108 IILEVAAIISLALSFYHPPEGDNAACGEVGGVEDEGESQAGWIEGAAILFSVIIVVLVTAFNDWS 172

  Fly   169 ESKSSKIMESFKNMVPQFATVIREGEKLTLRAEDLVLGDVVEVKFGDRIPADIRIIEARNFKVDN 233
            :.|..:.::|......:| ||||:|:.:.:...::|:||:.::|:||.:|||..:|:..:.|:|.
Zfish   173 KEKQFRGLQSRIEQEQKF-TVIRKGQVIQIPVAEIVVGDIAQIKYGDLLPADGILIQGNDLKIDE 236

  Fly   234 SSLTGESEPQSRGAEFTHENPLETKNLAFFSTNAVEGTAKGVVISCGDHTVMGRIAGLASGLDTG 298
            |||||||:...:.        ||...:....|:.:||:.:.||.:.|.::..|.|..|....:..
Zfish   237 SSLTGESDQVRKS--------LEKDPMLLSGTHVMEGSGRMVVSAVGLNSQTGIIFTLLGAGEDE 293

  Fly   299 ETPIAK--EIHHF 309
            |..:.|  .:.||
Zfish   294 EKKVKKGENLKHF 306

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Atpalpha	NP_732572.1	ATPase-IIC_X-K	45..1041	CDD:273445	71/273 (26%)
		Cation_ATPase_N	58..132	CDD:214842	17/69 (25%)
		E1-E2_ATPase	152..383	CDD:278548	46/161 (29%)
		Cation_ATPase	445..539	CDD:289987
		COG4087	<695..770	CDD:226572
		Cation_ATPase_C	817..1025	CDD:279079
atp2b4	NP_001070935.1	Cation_ATPase_N	47..117	CDD:279080	19/73 (26%)
atp2b4	NP_001070935.1	E1-E2_ATPase	153..>287	CDD:278548	41/142 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53587
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010