Protein Alignment Atpalpha and Atp2b1

DIOPT Version :9

• Sequence 1: NP_732572.1
• Gene: Atpalpha / 48971
• FlyBaseID: FBgn0002921
• Length: 1041
• Species: Drosophila melanogaster
• Sequence 2: NP_001346435.1
• Gene: Atp2b1 / 67972
• MGIID: 104653
• Length: 1249
• Species: Mus musculus
• Alignment Length: 1099
• Identity: 300/1099 - (27%)
• Similarity: 476/1099 - (43%)
• Gaps: 295/1099 - (26%)

  Fly    72 RFQTHPENGLSHAKAKENLERD----GPNALTPPKQTPEWVKFCKNLFGGFAMLLW-----IGAI 127
            :.:|.|..|||...|  :|||.    |.|.: |||:...           |..|:|     :..|
Mouse    62 KLKTSPNEGLSGNPA--DLERREAVFGKNFI-PPKKPKT-----------FLQLVWEALQDVTLI 112

  Fly   128 LCFVA--YSIQASTSEEPADDNLYLG--------------------IVLSAV-VIVTGIFSYYQE 169
            :..:|  .|:..|..:.|..||...|                    |:||.| |::...|:.:.:
Mouse   113 ILEIAAIVSLGLSFYQPPEGDNALCGEVSVGEEEGEGETGWIEGAAILLSVVCVVLVTAFNDWSK 177

  Fly   170 SKSSKIMESFKNMVPQFATVIREGEKLTLRAEDLVLGDVVEVKFGDRIPADIRIIEARNFKVDNS 234
            .|..:.::|......:| ||||.|:.:.:...|:.:||:.:||:||.:|||..:|:..:.|:|.|
Mouse   178 EKQFRGLQSRIEQEQKF-TVIRGGQVIQIPVADITVGDIAQVKYGDLLPADGILIQGNDLKIDES 241

  Fly   235 SLTGESEPQSRGAEFTHENPLETKNLAFFSTNAVEGTAKGVVISCGDHTVMGRIAGL-------- 291
            ||||||:...:.        |:...|....|:.:||:.:.||.:.|.::..|.|..|
Mouse   242 SLTGESDHVKKS--------LDKDPLLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEE 298

  Fly   292 ----------------------------------------ASGLDTGE----------------- 299
                                                    ..|.|..|
Mouse   299 EKKDEKKKEKKNKKQDGAIENRNKAKAQDGAAMEMQPLKSEEGGDGDEKDKKKANLPKKEKSVLQ 363

  Fly   300 ---TPIAKEIHHFIHLITGVAVFLGVTFFVI--AFILGYHWLD----------AVIFLIG--IIV 347
               |.:|.:|.....|::.:.|.:.|.:|||  .::....||.          ...|:||  ::|
Mouse   364 GKLTKLAVQIGKAGLLMSAITVIILVLYFVIDTFWVQKRPWLAECTPIYIQYFVKFFIIGVTVLV 428

  Fly   348 ANVPEGLLATVTVCLTLTAKRMASKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFD 412
            ..|||||...||:.|..:.|:|...|.||::|:|.||:|:.:.||||||||||.|||||...:.:
Mouse   429 VAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYIN 493

  Fly   413 NQIIEADTTEDQSGVQYDRTSPGFKAL---------SRIATLCNRA------EFKGGQDGVPILK 462
            .:             .|.:. |..:|:         :.|:..|...      |.:||      |.
Mouse   494 EK-------------HYKKV-PEPEAIPPNILSYLVTGISVNCAYTSKILPPEKEGG------LP 538

  Fly   463 KEVSGDASEAALLKCMELALGDVMNIRKRNKKIA-EVP---------FNSTNKYQVSIHETEDTN 517
            :.| |:.:|.||       ||.::::::..:.:. |:|         |||..|   |:......:
Mouse   539 RHV-GNKTECAL-------LGFLLDLKRDYQDVRNEIPEEALYKVYTFNSVRK---SMSTVLKNS 592

  Fly   518 DPRYLLVMKGAPERILERCSTIF-INGKEKVL-----DEEMKEAFNNAYMELGGLGERVLGFCDF 576
            |..:.:..|||.|.||::|..|. .||:.||.     |:.:|........|  ||....|.|.||
Mouse   593 DGSFRIFSKGASEIILKKCFKILSANGEAKVFRPRDRDDIVKTVIEPMASE--GLRTICLAFRDF 655

  Fly   577 MLPSDKYPNGFKFNTDDINFPIDNLRFVGLMSMIDPPRAAVPDAVAKCRSAGIKVIMVTGDHPIT 641
              |:.: |.....|.:|:   :..|..:.::.:.||.|..||:|:.||:.|||.|.|||||:..|
Mouse   656 --PAGE-PEPEWDNENDV---VTGLTCIAVVGIEDPVRPEVPEAIKKCQRAGITVRMVTGDNINT 714

  Fly   642 AKAIAKSVGIISEGNETV----EDIAQRLNIPVSEVNPREAKAAVVHGAELRDVSSDQLDEI--- 699
            |:|||...||:..|.:.:    :|..:|:         |..|.         ::..:::|:|
Mouse   715 ARAIATKCGILHPGEDFLCLEGKDFNRRI---------RNEKG---------EIEQERIDKIWPK 761

  Fly   700 LRYHTEIVFARTSPQQKLIIVEGC-------QRMGAIVAVTGDGVNDSPALKKADIGVAMGIAGS 757
            ||     |.||:||..|..:|:|.       ||.  :|||||||.||.|||||||:|.||||||:
Mouse   762 LR-----VLARSSPTDKHTLVKGIIDSTVSEQRQ--VVAVTGDGTNDGPALKKADVGFAMGIAGT 819

  Fly   758 DVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEISPFLAF----ILCDIPL 818
            ||:|:|:|:||.||||.|||..|..||.::|::.|.:.:.||.|:  ::..:||    |..|.||
Mouse   820 DVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNV--VAVIVAFTGACITQDSPL 882

  Fly   819 PLGTVTILCIDLGTDMVPAISLAYEHAEADIMKRPP---RDPFNDKLVNSRLISMAYGQIGMIQA 880
            .  .|.:|.::|..|.:.:::||.|.....::.|.|   ..|...:.:...::..|:.|:
Mouse   883 K--AVQMLWVNLIMDTLASLALATEPPTESLLLRKPYGRNKPLISRTMMKNILGHAFYQL----- 940

  Fly   881 AAGFFVYFVIMAENGFLPKKLFGIRK----------------MWDSKAVNDLTDSYGQEWTYRDR 929
                .|.|.::    |..:|.|.|..                ::::..:..|.:.......:.:|
Mouse   941 ----VVVFTLL----FAGEKFFDIDSGRNAPLHAPPSEHYTIVFNTFVLMQLFNEINARKIHGER 997

  Fly   930 KTLEYTCHTAFFISIV----VVQWADLIICK--TRRNSIFQQGMRNWALNFGLVFETVL 982
            ...|...:.|.|.:||    |||   :||.:  .:..|..:..:..|..:..|...|:|
Mouse   998 NVFEGIFNNAIFCTIVLGTFVVQ---IIIVQFGGKPFSCSELSIEQWLWSIFLGMGTLL 1053

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atpalpha	NP_732572.1	ATPase-IIC_X-K	45..1041	CDD:273445	300/1099 (27%)
		Cation_ATPase_N	58..132	CDD:214842	18/68 (26%)
		E1-E2_ATPase	152..383	CDD:278548	78/313 (25%)
		Cation_ATPase	445..539	CDD:289987	27/109 (25%)
		COG4087	<695..770	CDD:226572	44/84 (52%)
		Cation_ATPase_C	817..1025	CDD:279079	37/191 (19%)
Atp2b1	NP_001346435.1	ATPase-IIB_Ca	15..1064	CDD:273668	300/1099 (27%)
		ATP_Ca_trans_C	1103..1178	CDD:372101

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53587
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010