Protein Alignment Atpalpha and atp2a1l

DIOPT Version :9

• Sequence 1: NP_732572.1
• Gene: Atpalpha / 48971
• FlyBaseID: FBgn0002921
• Length: 1041
• Species: Drosophila melanogaster
• Sequence 2: XP_005156129.1
• Gene: atp2a1l / 494489
• ZFINID: ZDB-GENE-041229-2
• Length: 993
• Species: Danio rerio
• Alignment Length: 1068
• Identity: 314/1068 - (29%)
• Similarity: 475/1068 - (44%)
• Gaps: 180/1068 - (16%)

  Fly    60 DFHKISPEELYQRFQTHPENGLSHAKAKENLERDGPNALTPPKQTPEWVKFCKNLFGGFAMLLWI 124
            |.|...|.|....|......|||..:.|:||.:.|.|.|...:....|....:........:|.:
Zfish     3 DAHTKGPAECLAYFSVSETTGLSPEQFKKNLAKYGYNELPAEEGKSIWELIIEQFEDLLVRILLL 67

  Fly   125 GAILCFVAYSIQASTSE-----EPADDNLYLGIVLSAVVIVTGIFSYYQESKSSKIMESFKNMVP 184
            .|.:.||....:.....     ||        .|:..::|...:...:||..:...:|:.|...|
Zfish    68 AACISFVLAWFEEGEETITAFVEP--------FVILLILIANAVVGVWQERNAESAIEALKEYEP 124

  Fly   185 QFATVIREGEKLT--LRAEDLVLGDVVEVKFGDRIPADIRI--IEARNFKVDNSSLTGESEPQSR 245
            :...|.|...|..  ::|.::|.||:|||..||::||||||  |.:...:||.|.|||||.
Zfish   125 EMGKVYRSDRKSVQMIKAREIVPGDIVEVSVGDKVPADIRITHIRSTTLRVDQSILTGESV---- 185

  Fly   246 GAEFTHENPL--------ETKNLAFFSTNAVEGTAKGVVISCGDHTVMGRIAGLASGLDTGETPI 302
             :...|..|:        :.||:.|..||...|.|.||.::.|..|.:|:|....:..:..:||:
Zfish   186 -SVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKAVGVAVATGVATEIGKIRDQMAATEQEKTPL 249

  Fly   303 AKEIHHFIHLITGVAVFLGVTFFVIAF------ILGYHWLDAVIF----LIGIIVANVPEGLLAT 357
            .:::..|...::.|...:.|..::|..      :.|..|:...::    .:.:.||.:||||.|.
Zfish   250 QQKLDEFGEQLSKVISLICVAVWMINIGHFNDPVHGGSWIRGAVYYFKIAVALAVAAIPEGLPAV 314

  Fly   358 VTVCLTLTAKRMASKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMW----FDNQIIEA 418
            :|.||.|..:|||.||.:|::|.:|||||.||.||||||||||.|:|.|..|:    .|...:|.
Zfish   315 ITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMCVTKMFVIDRIDGDHVEL 379

  Fly   419 DTTEDQSGVQY----DRTSPGFKA----------LSRIATLCNRAEFKGGQDGVPILKK--EVSG 467
            |:. |.||.:|    :.|..|.|.          |:.|..|||.:.....:     .||  |..|
Zfish   380 DSF-DISGSKYTPEGEVTKLGAKVDCSQYDGLVELATICALCNDSSLDYNE-----TKKIYEKVG 438

  Fly   468 DASEAALLKCMELALGDVMNIRKRN-----------------KKIAEVPFN---STNKYQVSIHE 512
            :|:|.||  |   .|.:.||:.|.|                 |::.:..|.   |.::..:|::.
Zfish   439 EATETAL--C---CLVEKMNVFKSNVGNLSKVERANACCSVVKQLMKKNFTLEFSRDRKSMSVYC 498

  Fly   513 TEDTNDPRYLLVMKGAPERILERCSTIFINGKEKVLDEEMKEAFNNAYMELGGLGERVLGFCDFM 577
            |....|....:.:|||||.:::||:.:.:......|...:|:...|...| .|.|...|. |..:
Zfish   499 TPVKGDAGSKMFVKGAPEGVIDRCTYVRVGSTRVPLTGAVKDKIMNVIKE-WGTGRDTLR-CLAL 561

  Fly   578 LPSDKYPNGFKFNTDDINFPID---NLRFVGLMSMIDPPRAAVPDAVAKCRSAGIKVIMVTGDHP 639
            ...|......:.|.:|.....|   :|.|||.:.|:||||..|..::..||:|||:|||:|||:.
Zfish   562 ATRDSPLKVEEMNLEDSTKFADYETDLTFVGCVGMLDPPRKEVTGSIELCRAAGIRVIMITGDNK 626

  Fly   640 ITAKAIAKSVGIISEGNETVEDIAQRLNIPVSEVNPREAKAAVVHGAELRDVSSDQLDEILRYHT 704
            .||.||.:.:||.||.    ||:.              .||..  |.|..|:...:..|.:|  .
Zfish   627 GTAVAICRRIGIFSED----EDVT--------------GKAYT--GREFDDLPHSEQSEAVR--R 669

  Fly   705 EIVFARTSPQQKLIIVEGCQRMGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILL 769
            ...|||..|..|..|||..|....|.|:|||||||:||||||:||:||| :|:.|:|.|::|:|.
Zfish   670 ACCFARVEPSHKSKIVEFLQGYDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSASEMVLA 733

  Fly   770 DDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEISPFLAFILCDIPLPLGTVTILCIDLGTDM 834
            ||||:|||..|||||.|::|:|:.|.|.::|||.|:..........:|..|..|.:|.::|.||.
Zfish   734 DDNFSSIVAAVEEGRAIYNNMKQFIRYLISSNIGEVVCIFLTAALGLPEALIPVQLLWVNLVTDG 798

  Fly   835 VPAISLAYEHAEADIMKRPPRDPFNDKLVNSRLISM-----AYGQIGMIQAAAGFFVYFVIMAEN 894
            :||.:|.:...:.:||.:|||.| .:.|::..|...     ||.....:.|||.:|:|
Zfish   799 LPATALGFNPPDLEIMGKPPRSP-KEPLISGWLFFRYMTVGAYVGAATVAAAAYWFIY------- 855

  Fly   895 GFLPKKLFGIRKMWDSKAVNDLTDSYGQEWTYRDRKTLEYTCH--------------------TA 939
                                   |..|.:.||...... ..||                    |.
Zfish   856 -----------------------DEEGPQVTYYQLSHF-MQCHEENEDFTGIECEVFEACPPMTM 896

  Fly   940 FFISIVVVQWADLIICKTRRNSIFQQ--GMRNWALNFGLVFETVLAAFLSYCPGMEKGLRMYPLK 1002
            ....:|.::..:.:...:...|:.:.  ....|.|: .:.....|...:.|...|....|:..|.
Zfish   897 ALSVLVTIEMCNALNSLSENQSLVRMPPWSNGWLLS-AMTLSMSLHFMIIYVDPMPMIFRLTHLN 960

  Fly  1003 LVWWFPAIPFALAIFIYDETRRFYLRRN 1030
            ...||..:..:..:.:.||..:| |.||
Zfish   961 TEQWFVVLKLSFPVILIDEMLKF-LARN 987

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atpalpha	NP_732572.1	ATPase-IIC_X-K	45..1041	CDD:273445	314/1068 (29%)
		Cation_ATPase_N	58..132	CDD:214842	18/71 (25%)
		E1-E2_ATPase	152..383	CDD:278548	75/252 (30%)
		Cation_ATPase	445..539	CDD:289987	30/115 (26%)
		COG4087	<695..770	CDD:226572	37/74 (50%)
		Cation_ATPase_C	817..1025	CDD:279079	45/234 (19%)
atp2a1l	XP_005156129.1	Cation_ATPase_N	4..72	CDD:279080	16/67 (24%)
		ATPase-IIA1_Ca	53..986	CDD:273452	297/1015 (29%)
		E1-E2_ATPase	93..340	CDD:278548	75/251 (30%)
		Cation_ATPase	419..525	CDD:289987	30/115 (26%)
		HAD	<608..709	CDD:289480	48/122 (39%)
		Cation_ATPase_C	781..984	CDD:279079	46/236 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53587
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920