Protein Alignment Atpalpha and SPoCk

DIOPT Version :9

• Sequence 1: NP_732572.1
• Gene: Atpalpha / 48971
• FlyBaseID: FBgn0002921
• Length: 1041
• Species: Drosophila melanogaster
• Sequence 2: NP_001262220.1
• Gene: SPoCk / 40495
• FlyBaseID: FBgn0052451
• Length: 1062
• Species: Drosophila melanogaster
• Alignment Length: 1126
• Identity: 310/1126 - (27%)
• Similarity: 487/1126 - (43%)
• Gaps: 250/1126 - (22%)

  Fly    35 KSRRKMP--AKVNKKENLDDLKQ--ELDIDFHK---------ISPE--------------ELYQR 72
            |..|.:|  .|..|..::.|.|:  |.::|...         ::||              |:..|
  Fly    58 KDSRAVPQNVKPGKVADMKDCKEPDEDNVDQQNGNIIQTGLTLTPEMLLSTSESSTHSASEVAGR 122

  Fly    73 FQTHPENGLSHAKAKENLERDGPNALTPPKQTPEWVKFCKNLFGGFAMLLWIGAILCFVAYSIQA 137
            .|.....||...:||...:..|.|.|....:.|.|.|:.:. |....:||.:|:.|        .
  Fly   123 LQVDVRTGLKWTEAKYRAKIIGHNELLLVAEDPTWKKYIEQ-FRNPLILLLLGSAL--------V 178

  Fly   138 STSEEPADDNLYLGIVLSAVVIVTGIFSYYQESKSSKIMESFKNMVPQFATVIREGEKLTLRAED 202
            |...:..||.:.:.|.:..||.|    ::.||.:|.|.:|..|.:||.....:|||...|..|.:
  Fly   179 SVIMKQFDDAVSITIAILIVVTV----AFIQEYRSEKSLEELKKLVPPECHCLREGRLDTFLARE 239

  Fly   203 LVLGDVVEVKFGDRIPADIRIIEARNFKVDNSSLTGESEPQSRGAEF--------THENPLETKN 259
            ||.||:|.:..|||:|||:|:.||.:..:|.||.|||:||..:..:.        .|.|   .||
  Fly   240 LVPGDIVHLNVGDRVPADVRLFEAVDLSIDESSFTGETEPARKITDVLLNNTNVKDHSN---MKN 301

  Fly   260 LAFFSTNAVEGTAKGVVISCGDHTVMGRIAGLASGLDTGETPIAK-------EIHHFIHLITGVA 317
            :||..|....|..||:|:|.|:.:..|.:..:....:..:||:.|       ::..:..||.||.
  Fly   302 IAFMGTLVRCGNGKGIVVSTGERSEFGEVFKMMQAEEAPKTPLQKSMDILGAQLSFYSFLIIGVI 366

  Fly   318 VFLGVTFFVIAFILGYHWLD----AVIFLIGI--IVANVPEGLLATVTVCLTLTAKRMASKNCLV 376
            :.||             ||.    :.:|.|.:  .||.:||||...|||.|.|...|||.:|.:|
  Fly   367 MLLG-------------WLQGKPLSEMFNISVSLAVAAIPEGLPIVVTVTLALGVMRMAKRNSIV 418

  Fly   377 KNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIIEADTTEDQSGVQYDRTSPGFK---- 437
            |.|..|||||..:.||||||||||:|.||.      ..||.:|      |...|.|..|:.
  Fly   419 KKLPTVETLGCVNVICSDKTGTLTKNEMTA------TIIITSD------GYMADVTGAGYNDQGE 471

  Fly   438 -----------------ALSRIATLCNRAEFKGGQDGVPILKKEVSGDASEAALLKCMELALGDV 485
                             .|..|..:||.|..:.|         .:.|..:|.||   :.:|:.:.
  Fly   472 IHIRHCNNVEMAKTNITNLLEIGAVCNNAYIQNG---------TLLGQPTEGAL---VAVAMKNG 524

  Fly   486 MNIRKRN-KKIAEVPFNSTNKYQV--SIHETEDTNDPRYLLVMKGAPERILERCSTIFINGKEKV 547
            |.....| .:|.|.||:|..|...  .||:.  .|:...:...|||.|.:|.:|:......:...
  Fly   525 MYATAENYVRIQEYPFSSEQKMMAVKCIHKY--NNNKEEIFFAKGALETLLPQCTKYQFGTQTVP 587

  Fly   548 LDEEMKEAFNNAYMELGGLGERVLGFCDFMLPSDKYPNGFKFNTDDINFPIDNLRFVGLMSMIDP 612
            |.::.:..|.....|:|..|.|||....                   ...:.:|.:.||:.:.||
  Fly   588 LTKQNEAEFLAEAYEIGRKGLRVLALAK-------------------GRSMQDLIYCGLVGITDP 633

  Fly   613 PRAAVPDAVAKCRSAGIKVIMVTGD-------------------HPITAKAIAKSVGIISE---- 654
            ||..|.:::.....:|::|.|||||                   |.|.|...|..|.:.|.
  Fly   634 PRPLVRESIEMLMQSGVRVKMVTGDAQETALAIDPSRRLQAVPTHAIPAWPTAGGVPLCSASACC 698

  Fly   655 GNETVED---------IAQRLNIPVSEVNPREAKAAVVH-----GAELRDVSSDQLDEILRYHTE 705
            ....:|:         :||: .:|:  |.........:|     |.|:..::..|||::.  :..
  Fly   699 STNCLENAMKEIYLTALAQQ-GLPL--VTANLIGIDTIHHQTLSGQEMDQMNEHQLDKVA--NNV 758

  Fly   706 IVFARTSPQQKLIIVEGCQRMGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLD 770
            .||.|.||:.||.||:..||.|.||.:|||||||..||||||||:|||..|:||.|:||||||::
  Fly   759 SVFYRVSPRHKLEIVKSLQRSGNIVGMTGDGVNDGVALKKADIGIAMGKNGTDVCKEAADMILVN 823

  Fly   771 DNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEISPFLAFILCDIPLPLGTVTILCIDLGTDMV 835
            |:|.:|:..:|||:.||.|::..:.:.|:::|..::......|.||..||..:.||.|::..|..
  Fly   824 DDFHTIIAAIEEGKGIFYNIRNFVRFQLSTSIAALALIALATLMDIANPLNAMQILWINIIMDGP 888

  Fly   836 PAISLAYEHAEADIMKRPPRDPFNDKLVNSRLISMAYGQIGMIQAAAGFFVYFVIMAENGFLPKK 900
            ||.||..|..:.|::|:.||:.....:..|.::                         |..|...
  Fly   889 PAQSLGVEPVDHDVLKQKPRNVKQPMITKSVVV-------------------------NVLLSAS 928

  Fly   901 LFGIRKMWDSKAVNDLTD-SYGQEWTYRDRKTLEYTCHTAFFISIVVVQWADLIICKTRRNSIFQ 964
            :..:..:|..:  .::.| :.|:  |.|| .|:.:||...|       ...:.:.|:::..|:|.
  Fly   929 IIVLGTLWVFQ--REMADGTLGK--TKRD-TTMTFTCFVFF-------DMFNALSCRSQTKSVFT 981

  Fly   965 QGM-RNWALNFGLVFETVLAAFLSYCPGMEKGLRMYPLKLVWWFPAI-PFAL--------AIFIY 1019
            .|: .|......:.|..:....:.|.|         ||::|:...|: |:.:        ::.:.
  Fly   982 IGLTTNRMFLLAVAFSIIGQMLVVYFP---------PLQMVFQTEALTPYDIFFLVSLTSSVLVV 1037

  Fly  1020 DETRRFYLRRNPGGWLEQETY 1040
            .|.::::.|.     :|::.|
  Fly  1038 SEIKKWFERT-----MERKMY 1053

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atpalpha	NP_732572.1	ATPase-IIC_X-K	45..1041	CDD:273445	306/1114 (27%)
		Cation_ATPase_N	58..132	CDD:214842	21/96 (22%)
		E1-E2_ATPase	152..383	CDD:278548	84/251 (33%)
		Cation_ATPase	445..539	CDD:289987	26/96 (27%)
		COG4087	<695..770	CDD:226572	45/74 (61%)
		Cation_ATPase_C	817..1025	CDD:279079	42/218 (19%)
SPoCk	NP_001262220.1	ATPase-IIA2_Ca	110..1049	CDD:130585	297/1068 (28%)
		Cation_ATPase_N	112..179	CDD:279080	18/75 (24%)
		E1-E2_ATPase	191..425	CDD:278548	84/253 (33%)
		Cation_ATPase	496..579	CDD:289987	26/96 (27%)
		COG4087	<760..823	CDD:226572	42/62 (68%)
		Cation_ATPase_C	872..1044	CDD:279079	42/217 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	67	1.000	Domainoid score	I532
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm51342
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910