Protein Alignment Atpalpha and atp1a1

DIOPT Version :9

• Sequence 1: NP_732572.1
• Gene: Atpalpha / 48971
• FlyBaseID: FBgn0002921
• Length: 1041
• Species: Drosophila melanogaster
• Sequence 2: NP_989407.1
• Gene: atp1a1 / 395044
• XenbaseID: XB-GENE-484831
• Length: 1023
• Species: Xenopus tropicalis
• Alignment Length: 1035
• Identity: 769/1035 - (74%)
• Similarity: 892/1035 - (86%)
• Gaps: 14/1035 - (1%)

  Fly     7 YEHGRADSYRVATVIATDDDNRTADGQYKSRRKMPAKVNKKENLDDLKQELDIDFHKISPEELYQ 71
            |..|| |.|..|   ||.:     .|..|.:.|     .|.:::|:||:||.::.||:|.:||::
 Frog     3 YGAGR-DKYEPA---ATSE-----QGGKKKKGK-----GKDKDMDELKKELTMEDHKLSLDELHR 53

  Fly    72 RFQTHPENGLSHAKAKENLERDGPNALTPPKQTPEWVKFCKNLFGGFAMLLWIGAILCFVAYSIQ 136
            :|.|..:.|||.|:|.|.|.||||||||||..||||||||:.|||||:|||||||||||:||.|.
 Frog    54 KFGTDMQRGLSTARAAEILARDGPNALTPPPTTPEWVKFCRQLFGGFSMLLWIGAILCFLAYGIT 118

  Fly   137 ASTSEEPADDNLYLGIVLSAVVIVTGIFSYYQESKSSKIMESFKNMVPQFATVIREGEKLTLRAE 201
            |:|.|||.:||||||:|||||||:||.||||||:|||||||||||||||.|.|||.||||::.||
 Frog   119 AATEEEPTNDNLYLGVVLSAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVIRNGEKLSINAE 183

  Fly   202 DLVLGDVVEVKFGDRIPADIRIIEARNFKVDNSSLTGESEPQSRGAEFTHENPLETKNLAFFSTN 266
            |:||||:||||.|||||||:|||.|...||||||||||||||:|..:||:||||||:|:||||||
 Frog   184 DVVLGDLVEVKGGDRIPADVRIISAHGCKVDNSSLTGESEPQTRSPDFTNENPLETRNIAFFSTN 248

  Fly   267 AVEGTAKGVVISCGDHTVMGRIAGLASGLDTGETPIAKEIHHFIHLITGVAVFLGVTFFVIAFIL 331
            .|||||:|||::.||.|||||||.|||||:.|.||||.||.||||:||||||||||:||:::.||
 Frog   249 CVEGTARGVVVNTGDRTVMGRIATLASGLEGGRTPIAIEIEHFIHIITGVAVFLGVSFFILSLIL 313

  Fly   332 GYHWLDAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMASKNCLVKNLEAVETLGSTSTICSDKT 396
            .|.||:|||||||||||||||||||||||||||||||||.|||||||||||||||||||||||||
 Frog   314 QYTWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKT 378

  Fly   397 GTLTQNRMTVAHMWFDNQIIEADTTEDQSGVQYDRTSPGFKALSRIATLCNRAEFKGGQDGVPIL 461
            |||||||||||||||||||.||||||:|||..:|::||.:.||||:|.|||||.|:.||:..|||
 Frog   379 GTLTQNRMTVAHMWFDNQIHEADTTENQSGASFDKSSPTWTALSRVAGLCNRAVFQAGQENTPIL 443

  Fly   462 KKEVSGDASEAALLKCMELALGDVMNIRKRNKKIAEVPFNSTNKYQVSIHETEDTNDPRYLLVMK 526
            |::|:|||||:|||||:||..|.|.::|::|.|:||:|||||||||:|:|:..:.::.||:||||
 Frog   444 KRDVAGDASESALLKCIELCCGSVRDMREKNPKVAEIPFNSTNKYQLSVHKNANPSESRYILVMK 508

  Fly   527 GAPERILERCSTIFINGKEKVLDEEMKEAFNNAYMELGGLGERVLGFCDFMLPSDKYPNGFKFNT 591
            |||||||:|||||.:.|||:.||||:|:||.|||:|||||||||||||...|..|::|:||:|:|
 Frog   509 GAPERILDRCSTIVLQGKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLALSDDQFPDGFQFDT 573

  Fly   592 DDINFPIDNLRFVGLMSMIDPPRAAVPDAVAKCRSAGIKVIMVTGDHPITAKAIAKSVGIISEGN 656
            :::|||.:||.||||:||||||||||||||.|||||||||||||||||||||||||.||||||||
 Frog   574 EEVNFPTENLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGN 638

  Fly   657 ETVEDIAQRLNIPVSEVNPREAKAAVVHGAELRDVSSDQLDEILRYHTEIVFARTSPQQKLIIVE 721
            |||||||.||||||::||||:|||.|:||::|:|::.:|:|:||::|||||||||||||||||||
 Frog   639 ETVEDIAARLNIPVNQVNPRDAKACVIHGSDLKDMAQEQIDDILKHHTEIVFARTSPQQKLIIVE 703

  Fly   722 GCQRMGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLI 786
            ||||.|||||||||||||||||||||||:||||||||||||||||||||||||||||||||||||
 Frog   704 GCQRQGAIVAVTGDGVNDSPALKKADIGIAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLI 768

  Fly   787 FDNLKKSIAYTLTSNIPEISPFLAFILCDIPLPLGTVTILCIDLGTDMVPAISLAYEHAEADIMK 851
            |||||||||||||||||||:|||.||:.:||||||||||||||||||||||||||||.||:||||
 Frog   769 FDNLKKSIAYTLTSNIPEITPFLIFIVANIPLPLGTVTILCIDLGTDMVPAISLAYEQAESDIMK 833

  Fly   852 RPPRDPFNDKLVNSRLISMAYGQIGMIQAAAGFFVYFVIMAENGFLPKKLFGIRKMWDSKAVNDL 916
            |.||:|..|||||.|||||||||||||||..|||.||||:|||||||..|.|||..||.:..||:
 Frog   834 RQPRNPKTDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPWTLLGIRVNWDDRWNNDV 898

  Fly   917 TDSYGQEWTYRDRKTLEYTCHTAFFISIVVVQWADLIICKTRRNSIFQQGMRNWALNFGLVFETV 981
            .|||||:|||..||.:|:|||||||:|||||||||||||||||||:|||||:|..|.|||..||.
 Frog   899 EDSYGQQWTYEQRKIVEFTCHTAFFVSIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLFEETA 963

  Fly   982 LAAFLSYCPGMEKGLRMYPLKLVWWFPAIPFALAIFIYDETRRFYLRRNPGGWLEQETYY 1041
            |||||||||||:..|||||||..|||.|.|::|.||||||.|:..:||:||||:|:||||
 Frog   964 LAAFLSYCPGMDVALRMYPLKPTWWFCAFPYSLLIFIYDEVRKLIIRRSPGGWVEKETYY 1023

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atpalpha	NP_732572.1	ATPase-IIC_X-K	45..1041	CDD:273445	756/995 (76%)
		Cation_ATPase_N	58..132	CDD:214842	48/73 (66%)
		E1-E2_ATPase	152..383	CDD:278548	183/230 (80%)
		Cation_ATPase	445..539	CDD:289987	59/93 (63%)
		COG4087	<695..770	CDD:226572	68/74 (92%)
		Cation_ATPase_C	817..1025	CDD:279079	159/207 (77%)
atp1a1	NP_989407.1	ATPase-IIC_X-K	32..1023	CDD:273445	755/990 (76%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	335	1.000	Domainoid score	I1133
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	1570	1.000	Inparanoid score	I90
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D50082at33208
OrthoFinder	1	1.000	-	-		FOG0000283
OrthoInspector	1	1.000	-	-		otm48370
Panther	1	1.100	-	-	O	PTHR43294
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X416
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	8.160