Protein Alignment Atpalpha and atp2a2a

DIOPT Version :9

• Sequence 1: NP_732572.1
• Gene: Atpalpha / 48971
• FlyBaseID: FBgn0002921
• Length: 1041
• Species: Drosophila melanogaster
• Sequence 2: XP_005166855.1
• Gene: atp2a2a / 393940
• ZFINID: ZDB-GENE-040426-702
• Length: 1042
• Species: Danio rerio
• Alignment Length: 1093
• Identity: 318/1093 - (29%)
• Similarity: 493/1093 - (45%)
• Gaps: 214/1093 - (19%)

  Fly    62 HKISPEELYQRFQTHPENGLSHAKAKENLERDGPNALTPPKQTPEWVKFCKNLFGGFAMLLWIGA 126
            |..|.||:|..|..:...||:..:.|.|.::.|||.|...:....|....:........:|.:.|
Zfish     5 HTKSVEEVYSNFSVNESTGLTLDQVKRNRDKWGPNELPAEEGKSIWELVIEQFEDLLVRILLLAA 69

  Fly   127 ILCFVAYSIQASTSE-----EPADDNLYLGIVLSAVVIVTGIFSYYQESKSSKIMESFKNMVPQF 186
            .:.||....:.....     ||        .|:..::|...|...:||..:...:|:.|...|:.
Zfish    70 CISFVLAWFEEGEETITAFVEP--------FVILLILIANAIVGVWQERNAENAIEALKEYEPEM 126

  Fly   187 ATVIREGEKLT--LRAEDLVLGDVVEVKFGDRIPADIRI--IEARNFKVDNSSLTGESEPQSRGA 247
            ..|.|:..|..  ::|:|:|.||:|||..||::||||||  |::...:||.|.|||||.     :
Zfish   127 GKVYRQDRKSVQRIKAKDIVPGDIVEVAVGDKVPADIRISAIKSTTLRVDQSILTGESV-----S 186

  Fly   248 EFTHENPL--------ETKNLAFFSTNAVEGTAKGVVISCGDHTVMGRIAGLASGLDTGETPIAK 304
            ...|.:|:        :.||:.|..||...|.|.|||::.|.:|.:|:|....:..:...||:.:
Zfish   187 VIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAIGVVVATGVNTEIGKIRDEMASTEQERTPLQQ 251

  Fly   305 EIHHFIHLITGVAVFLGVTFFVIAF------ILGYHWLDAVIF----LIGIIVANVPEGLLATVT 359
            ::..|...::.|...:.:..::|..      :.|..|:...::    .:.:.||.:||||.|.:|
Zfish   252 KLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAVYYFKIAVALAVAAIPEGLPAVIT 316

  Fly   360 VCLTLTAKRMASKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMW-------------- 410
            .||.|..:|||.||.:|::|.:|||||.||.||||||||||.|:|:|..|:
Zfish   317 TCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFIIDKAEGENCSLTE 381

  Fly   411 ---------------FDNQIIEADTTEDQSGVQYDRTSPGFKALSRIATLCNRA-----EFKGGQ 455
                           .||:|::..        |||    |...|:.|..|||.:     |.||..
Zfish   382 FTISGSTYAPEGDVCLDNRIVKCS--------QYD----GLVELATICALCNDSSLDFNESKGVY 434

  Fly   456 DGVPILKKEVSGDASEAA---LLKCMELALGDVMNIRK------------------------RNK 493
            :.|        |:|:|.|   |::.|.:...||.|:.|                        |::
Zfish   435 EKV--------GEATETALTCLVEKMNVFDTDVRNLSKIERANACNAVIKQLMKKEFTLEFSRDR 491

  Fly   494 KIAEVPFNSTNKYQVSIHETEDTNDPRYLLVMKGAPERILERCSTIFINGKEKVLDEEMKEAFNN 558
            |...| :.|.||.:.|..:          :.:|||||.:::||:.:.:.|.:..|.:.:|:...:
Zfish   492 KSMSV-YCSPNKAKSSSSK----------MFVKGAPEGVIDRCAYVRVGGSKVPLTQGIKDKIMS 545

  Fly   559 AYMELGGLGERVLGFCDFMLPSDKYPNGFKFN----TDDINFP--IDNLRFVGLMSMIDPPRAAV 617
            ...|. |.|...|. |..:...|   |..|..    :|...|.  ..:|.|||.:.|:||||..|
Zfish   546 VIREY-GTGRDTLR-CLALATRD---NPLKKEEMVLSDTARFADYESDLTFVGCVGMLDPPRTEV 605

  Fly   618 PDAVAKCRSAGIKVIMVTGDHPITAKAIAKSVGIISEGNETVEDIAQRLNIPVSEVNPREAKAAV 682
            ..::..||.|||:|||:|||:..||.||.:.:||.|:     ||...|:               .
Zfish   606 AASIKLCRHAGIRVIMITGDNKGTAVAICRRIGIFSD-----EDDVHRM---------------A 650

  Fly   683 VHGAELRDVSSDQLDEILRYHTEIVFARTSPQQKLIIVEGCQRMGAIVAVTGDGVNDSPALKKAD 747
            ..|.|..|:|.....|.:.  ....|||..|..|..|||..|....|.|:|||||||:||||||:
Zfish   651 FTGREFDDLSPHAQREAVT--VARCFARVEPSHKSKIVEFLQGFDEITAMTGDGVNDAPALKKAE 713

  Fly   748 IGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEISPFLAFI 812
            ||:||| :|:.|:|.|::|:|.||||::||..|||||.|::|:|:.|.|.::||:.|:.......
Zfish   714 IGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTA 777

  Fly   813 LCDIPLPLGTVTILCIDLGTDMVPAISLAYEHAEADIMKRPPRDPFNDKLVNSRLISMAYGQIGM 877
            ....|..|..|.:|.::|.||.:||.:|.:...:.|||.:|||.. .:.|::..|. ..|..||.
Zfish   778 ALGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRSA-KEPLISGWLF-FRYLAIGC 840

  Fly   878 IQAAA--GFFVYFVIMAENGFLPK-KLFGIRKMWDSKAVNDLTDSYGQEWTYRDRKTLEYTCH-- 937
            ...||  |...::.|:|::|  |. .|:.:.........|.            |.:.||  ||
Zfish   841 YVGAATVGAAAWWFIVADDG--PMITLYQLSHFLQCSPDNP------------DFQDLE--CHVF 889

  Fly   938 ------TAFFISIVVVQWADLIICKTRRNSIFQQGMRNW---------ALNFGLVFETVLAAFLS 987
                  |.....:|.::..:.:...:...|:.:  |..|         .|:..|.|      .:.
Zfish   890 ESPYPMTMALSVLVTIEMCNALNSLSENQSLVR--MPPWENIWLLGAICLSMSLHF------LIL 946

  Fly   988 YCPGMEKGLRMYPLKLVWWFPAIPFALAIFIYDETRRFYLRR--NPGGWLEQE 1038
            |...:....::.||.:..|...:..:|.:.:.||..:|..|.  .||..|::|
Zfish   947 YVEPLPVIFQITPLNVTQWMMVLKISLPVILLDELLKFVARTYLEPGKDLKEE 999

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atpalpha	NP_732572.1	ATPase-IIC_X-K	45..1041	CDD:273445	318/1093 (29%)
		Cation_ATPase_N	58..132	CDD:214842	18/69 (26%)
		E1-E2_ATPase	152..383	CDD:278548	77/252 (31%)
		Cation_ATPase	445..539	CDD:289987	31/125 (25%)
		COG4087	<695..770	CDD:226572	36/74 (49%)
		Cation_ATPase_C	817..1025	CDD:279079	50/227 (22%)
atp2a2a	XP_005166855.1	Cation_ATPase_N	4..72	CDD:279080	17/66 (26%)
		ATPase-IIA1_Ca	53..987	CDD:273452	298/1031 (29%)
		E1-E2_ATPase	93..340	CDD:278548	77/251 (31%)
		Cation_ATPase	419..526	CDD:289987	31/125 (25%)
		HAD	<604..710	CDD:289480	47/127 (37%)
		Cation_ATPase_C	782..985	CDD:279079	50/228 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53587
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920