Protein Alignment Atpalpha and Atp13a2

DIOPT Version :10

• Sequence 1: NP_732572.1
• Gene: Atpalpha / 48971
• FlyBaseID: FBgn0002921
• Length: 1041
• Species: Drosophila melanogaster
• Sequence 2: NP_001424084.1
• Gene: Atp13a2 / 362645
• RGDID: 1307977
• Length: 1173
• Species: Rattus norvegicus
• Alignment Length: 920
• Identity: 217/920 - (23%)
• Similarity: 343/920 - (37%)
• Gaps: 222/920 - (24%)

  Fly    94 GPNALTPPKQTPEWVKFCKNL-----------FGGFAMLLWIGAILCFVAYSIQASTSEEPADDN 147
            |||.:..|      ||....|           |..|::.||:                   ||..
  Rat   212 GPNVIGIP------VKSYLQLLVDEALNPYYGFQAFSIALWL-------------------ADHY 251

  Fly   148 LYLGIVLSAVVIVTGIFSYYQESKSSKIMESFKNMVPQFATVIREGEKLTLRAEDLVLGD-VVEV 211
            .:..:.:..:..::...|.|:..|.|..:.....:..:.......||:..:.:.:||.|| :|..
  Rat   252 YWYAVCIFLISAISICLSLYKTRKQSMTLRDMVKLSVRVQVCRPGGEEEWVDSSELVPGDCLVLP 316

  Fly   212 KFGDRIPADIRIIEARNFKVDNSSLTGESEPQSRGAEFTHENPL----ET--KNLAFFSTNAVEG 270
            :.|..:|.|..:: |....|:.|||||||.|..:.|  ..|.|.    ||  ::..|..|..::.
  Rat   317 QEGGMMPCDAALV-AGECVVNESSLTGESIPVLKTA--LPEGPQPYCPETHRRHTLFCGTLVLQA 378

  Fly   271 TA------KGVVISCGDHTVMGRIAGLASGLDTGETPIA-KEIHHFIHLITGVAV--FLGVTFFV 326
            .|      ..||...|..|..|   ||.|.: ....||: |...|.:..:..::|  .||..:.:
  Rat   379 RAYLGPRVLAVVTRTGFCTAKG---GLVSSI-LHPRPISFKFYRHSMKFVAALSVLALLGTIYSI 439

  Fly   327 IAFILGYHWL---DAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMASKNCLVKNLEAVETLGST 388
            |  ||..:.:   :.||..:.::...||..|.|.:|||......|:.::.....:...:...|..
  Rat   440 I--ILYRNRVPVKEIVIRALDLVTVVVPPALPAAMTVCTLYAQSRLRTQGIFCIHPLRINLGGKL 502

  Fly   389 STICSDKTGTLTQNRMTVAHMWFDNQIIEADTTEDQSGV-------------QYDRTSPGFKALS 440
            ..:|.|||||||::.:                  |..||             :.....||  .|.
  Rat   503 RLVCFDKTGTLTEDGL------------------DIMGVVPLKGQMLLPLVPEPCHLPPG--PLL 547

  Fly   441 RIATLCNR-AEFKGGQDGVPILKKEV------------SGDASEAALLKCM----------ELAL 482
            |....|:. ::......|.|:..|.|            :|.|.|..:|..|          |.:.
  Rat   548 RALVTCHALSQLHDTLVGDPMDLKMVESTGWVLEEGSAAGSAPETQVLVVMRPPPRGPQQQEESP 612

  Fly   483 GDVMNIRKRNKKIAEVPFNST-NKYQVSIHETEDTNDPRYLLVMKGAPERILERCSTIFINGKEK 546
            ..|..:|:       .||:|. .:..|.:.....|....|   :||:||.:...||
  Rat   613 EPVSVLRR-------FPFSSALQRMDVVVTWPGATQPEAY---VKGSPELVASLCS--------- 658

  Fly   547 VLDEEMKEAFNNAYMELGGLGERVLGFCDFMLP-SDKYPNGFKFNTDDINFPIDNLRFVGLMSMI 610
              .|.:...|..........|.||:......|| :.......:...|.:.   ..|..:||:.|.
  Rat   659 --PETVPRDFPQVLQSYTAAGYRVVALAGKPLPTAPSLEAAQQLTRDTVE---QELSLLGLLVMR 718

  Fly   611 DPPRAAVPDAVAKCRSAGIKVIMVTGDHPITAKAIAKSVGIISEGNETVEDIA-------QRLNI 668
            :..:......:...|..||:.:|||||:..||..:||:.|::.    |.|.:|       ::...
  Rat   719 NLLKPQTTPVIQTLRKTGIRTVMVTGDNLQTAVTVAKACGMVG----TQEHLAIIHATHPEQGQP 779

  Fly   669 PVSEVNPREAKAAVVHGAELRDVSSDQLDE----------------ILRYH----------TEIV 707
            ...|..|.|..|| ::||:....::|...|                :|:.|          ...|
  Rat   780 AALEFLPTEPSAA-MNGAKDPVQATDYPVEPESQSRHLALSGSTFAVLQKHFPKLLPKVLVQATV 843

  Fly   708 FARTSPQQKLIIVEGCQRMGAIVAVTGDGVNDSPALKKADIGVAMGIA-GSDVSKQAADMILLDD 771
            |||.:|:||..:|...||:...|.:.|||.||..|||.||:|:::..| .|.||...:.|..::
  Rat   844 FARMAPEQKTQLVCELQRLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSPFTSSMASIE- 907

  Fly   772 NFASIVTGVEEGRLIFDN----LKKSIAYTLTSNIPEISPFLAFILCDIPLPLGTVTILCIDLG- 831
               .:.|.:.|||...|.    .|....|:||..|.      ..||..|...||.:..|.|||.
  Rat   908 ---CVPTVIREGRCSLDTSFSVFKYMALYSLTQFIS------VLILYTINTNLGDLQFLAIDLFI 963

  Fly   832 TDMV--------PAISLAYEHAEADIMKRPPRDPFNDKLVNSRLISMAYGQIGMIQAAAGFFVYF 888
            |..|        ||::|        :..|||....:..::.|.|:.:|.  :..||...    ||
  Rat   964 TTTVAVLMSRTGPALTL--------VRARPPGALLSVPVLGSLLLQVAL--VAGIQLGG----YF 1014

  Fly   889 VIMAENGFLP 898
            :::|:..|:|
  Rat  1015 LVIAQPWFVP 1024

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atpalpha	NP_732572.1	ATPase-IIC_X-K	45..1041	CDD:273445	217/920 (24%)
Atp13a2	NP_001424084.1	None