Protein Alignment Atpalpha and atp2a1

DIOPT Version :9

• Sequence 1: NP_732572.1
• Gene: Atpalpha / 48971
• FlyBaseID: FBgn0002921
• Length: 1041
• Species: Drosophila melanogaster
• Sequence 2: NP_001007030.1
• Gene: atp2a1 / 260440
• ZFINID: ZDB-GENE-020905-1
• Length: 994
• Species: Danio rerio
• Alignment Length: 1057
• Identity: 299/1057 - (28%)
• Similarity: 483/1057 - (45%)
• Gaps: 162/1057 - (15%)

  Fly    62 HKISPEELYQRFQTHPENGLSHAKAKENLERDGPNALTPPKQTPEWVKFCKNLFGGFAMLLWIGA 126
            |.....|....|......||:..:.|:|..:.|.|.|...:....|....:........:|.:.|
Zfish     5 HTKETPECLAYFGVSESTGLTPEQVKKNQAKYGFNELPAEEGKSIWELVVEQFEDLLVRILLLAA 69

  Fly   127 ILCFVAYSIQ-----ASTSEEPADDNLYLGIVLSAVVIVTGIFSYYQESKSSKIMESFKNMVPQF 186
            .:.||....:     .:...||        .|:..::|...:...:||..:...:|:.|...|:.
Zfish    70 CISFVLAWFEEGEETVTAFVEP--------FVILLILIANAVVGVWQERNAESAIEALKEYEPEM 126

  Fly   187 ATVIREGEKLT--LRAEDLVLGDVVEVKFGDRIPADIRI--IEARNFKVDNSSLTG--------- 238
            ..|.|...|..  ::|.::|.||:|||..||::||||||  |.:...:||.|.|||
Zfish   127 GKVYRSDRKSVQRIKAREIVPGDIVEVSVGDKVPADIRITAIRSTTLRVDQSILTGESVSVIKHT 191

  Fly   239 ESEPQSRGAEFTHENPLETKNLAFFSTNAVEGTAKGVVISCGDHTVMGRIAGLASGLDTGETPIA 303
            ||.|..|...      .:.||:.|..||...|.|.|||::.|..|.:|:|....:..:..:||:.
Zfish   192 ESVPDPRAVN------QDKKNMLFSGTNIAAGKAIGVVVATGVSTEIGKIRDQMAATEQEKTPLQ 250

  Fly   304 KEIHHFIHLITGVAVFLGVTFFVIAF------ILGYHWLDAVIF----LIGIIVANVPEGLLATV 358
            :::..|...::.|...:.|..::|..      :.|..|:...::    .:.:.||.:||||.|.:
Zfish   251 QKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWIRGAVYYFKIAVALAVAAIPEGLPAVI 315

  Fly   359 TVCLTLTAKRMASKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIIEADTTED 423
            |.||.|..:|||.||.:|::|.:|||||.||.||||||||||.|:|.|..|:...::.....|.|
Zfish   316 TTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMCVTKMFVIEKVEGESVTLD 380

  Fly   424 QSGVQYDRTSP-----------------GFKALSRIATLCNRA-----EFKGGQDGVPILKKEVS 466
            |..:...:.:|                 |...|:.|..|||.:     |.||..:.|
Zfish   381 QYDISGSKYTPEGEVTKNGLPVKCGQFDGLVELATICALCNDSSLDYNESKGIYEKV-------- 437

  Fly   467 GDASEAA---LLKCMELALGDVMNIRKRN---------KKIAEVPFN---STNKYQVSIH--ETE 514
            |:|:|.|   |::.|.:...||..:.|..         |::.:..|.   |.::..:|::  ..:
Zfish   438 GEATETALCCLVEKMNVFNTDVRGLSKVERANTCCAVIKQLMKKDFTLEFSRDRKSMSVYCSPAK 502

  Fly   515 DTNDP-RYLLVMKGAPERILERCSTIFINGKEKVLDEEMKEAFNNAYMELGGLGERVLGFCDFML 578
            .:..| ...:.:|||||.:::||:.:.:......|...:|:.. .|.::..|.|...|. |..:.
Zfish   503 ASKAPVGNKMFVKGAPEGVIDRCAYVRVGTTRVPLTGPVKDKI-MAVIKEWGTGRDTLR-CLALA 565

  Fly   579 PSDKYPNGFKFNTDD----INFPIDNLRFVGLMSMIDPPRAAVPDAVAKCRSAGIKVIMVTGDHP 639
            ..|......:.|.:|    ..:..| |.|||.:.|:||||..|..::..||:|||:|||:|||:.
Zfish   566 TRDNPLRPEEMNLEDSTKFAEYETD-LTFVGCVGMLDPPRKEVVGSIELCRAAGIRVIMITGDNK 629

  Fly   640 ITAKAIAKSVGIISEGNETVEDIAQRLNIPVSEVNPREAKAAVVHGAELRDVSSDQLDEILRYHT 704
            .||.||.:.:||.|:.    ||:..|                ...|.|..|:...|..|.:|  .
Zfish   630 GTAVAICRRIGIFSDD----EDVTGR----------------AFTGREFDDLPLPQQREAVR--K 672

  Fly   705 EIVFARTSPQQKLIIVEGCQRMGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILL 769
            ...:||..|..|..|||..|....|.|:|||||||:||||||:||:||| :|:.|:|.|::|:|.
Zfish   673 ACCYARVEPSHKSKIVEFLQGFDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSASEMVLA 736

  Fly   770 DDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEISPFLAFILCDIPLPLGTVTILCIDLGTDM 834
            ||||:|||..|||||.|::|:|:.|.|.::||:.|:..........:|..|..|.:|.::|.||.
Zfish   737 DDNFSSIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDG 801

  Fly   835 VPAISLAYEHAEADIMKRPPRDPFNDKLVNS----RLISMAYGQIG--MIQAAAGFFVYFVIMAE 893
            :||.:|.:...:.|||.:.||.| .:.|::.    |.:::. |.:|  .:.||..:|:|    .:
Zfish   802 LPATALGFNPPDLDIMGKAPRSP-KEPLISGWLFFRYLAIG-GYVGAATVAAAGWWFLY----CD 860

  Fly   894 NGFLPKKLFGIRKMWDSKAVNDLTDSYGQEWTYRDRKTLEYTCHTAFFISIVV-VQWADLIICKT 957
            .|.: ...:.:.......|.|:  |..|.|.     :..|........:|::| ::..:.:...:
Zfish   861 EGPM-VSFYQLSHFMQCTADNE--DFAGIEC-----EVFEAAPPMTMALSVLVTIEMCNALNSLS 917

  Fly   958 RRNSIFQQGMRNWALNFGLVFETVLAAFLSYCPGMEKGLRMY--PLKLVW---------WFPAIP 1011
            ...|:.:  |..|: |..|.....|:..|.:       :.:|  ||.:::         |...:.
Zfish   918 ENQSLLR--MPPWS-NLWLAGAMTLSMSLHF-------MIIYVDPLPMIFKLTHLNFDQWIVVLK 972

  Fly  1012 FALAIFIYDETRRFYLR 1028
            .:..:.:.||..:|..|
Zfish   973 LSFPVILIDEALKFVAR 989

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atpalpha	NP_732572.1	ATPase-IIC_X-K	45..1041	CDD:273445	299/1057 (28%)
		Cation_ATPase_N	58..132	CDD:214842	14/69 (20%)
		E1-E2_ATPase	152..383	CDD:278548	76/253 (30%)
		Cation_ATPase	445..539	CDD:289987	28/116 (24%)
		COG4087	<695..770	CDD:226572	37/74 (50%)
		Cation_ATPase_C	817..1025	CDD:279079	46/225 (20%)
atp2a1	NP_001007030.1	Cation_ATPase_N	4..72	CDD:279080	13/66 (20%)
		ATPase-IIA1_Ca	53..989	CDD:273452	287/1007 (29%)
		E1-E2_ATPase	93..340	CDD:278548	76/252 (30%)
		Cation_ATPase	419..528	CDD:289987	28/116 (24%)
		HAD	<604..712	CDD:289480	48/129 (37%)
		Cation_ATPase_C	784..987	CDD:279079	46/226 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53587
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920