Protein Alignment Atpalpha and Atp4a

DIOPT Version :10

• Sequence 1: NP_732572.1
• Gene: Atpalpha / 48971
• FlyBaseID: FBgn0002921
• Length: 1041
• Species: Drosophila melanogaster
• Sequence 2: NP_036641.1
• Gene: Atp4a / 24216
• RGDID: 2177
• Length: 1034
• Species: Rattus norvegicus
• Alignment Length: 1040
• Identity: 627/1040 - (60%)
• Similarity: 781/1040 - (75%)
• Gaps: 15/1040 - (1%)

  Fly    10 GRADSYRVATV-IATDDDNRTADGQYKSRRKMPAKV------NKKENLDDLKQELDIDFHKISPE 67
            |:|::|.:.:| :.|......|       .||..|.      .|||.|:::|:|::::.|::|..
  Rat     2 GKAENYELYSVELGTGPGGNMA-------AKMSKKKAGGGGGKKKEKLENMKKEMEMNDHQLSVS 59

  Fly    68 ELYQRFQTHPENGLSHAKAKENLERDGPNALTPPKQTPEWVKFCKNLFGGFAMLLWIGAILCFVA 132
            ||.|::||....||..:.|.|.|.|||||||.||:.|||:|||.:.|.||...|:|:.|.:|.:|
  Rat    60 ELEQKYQTSATKGLKASLAAELLLRDGPNALRPPRGTPEYVKFARQLAGGLQCLMWVAAAICLIA 124

  Fly   133 YSIQASTSEEPADDNLYLGIVLSAVVIVTGIFSYYQESKSSKIMESFKNMVPQFATVIREGEKLT 197
            ::||||..:...||||||.:.|.|||:|||.|.||||.||:.|:.||||:|||.|||||:|:|..
  Rat   125 FAIQASEGDLTTDDNLYLALALIAVVVVTGCFGYYQEFKSTNIIASFKNLVPQQATVIRDGDKFQ 189

  Fly   198 LRAEDLVLGDVVEVKFGDRIPADIRIIEARNFKVDNSSLTGESEPQSRGAEFTHENPLETKNLAF 262
            :.|:.||:||:||:|.|||:||||||:.|:..||||||||||||||:|..|.|||:||||:|:||
  Rat   190 INADQLVVGDLVEMKGGDRVPADIRILSAQGCKVDNSSLTGESEPQTRSPECTHESPLETRNIAF 254

  Fly   263 FSTNAVEGTAKGVVISCGDHTVMGRIAGLASGLDTGETPIAKEIHHFIHLITGVAVFLGVTFFVI 327
            |||..:||||:|:|:|.||.|::||||.||||::..:||||.||.||:.:|.|:|:..|.||||:
  Rat   255 FSTMCLEGTAQGLVVSTGDRTIIGRIASLASGVENEKTPIAIEIEHFVDIIAGLAILFGATFFVV 319

  Fly   328 AFILGYHWLDAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMASKNCLVKNLEAVETLGSTSTIC 392
            |..:||.:|.|::|.:.|:||.|||||||||||||:|||||:|||||:||||||||||||||.||
  Rat   320 AMCIGYTFLRAMVFFMAIVVAYVPEGLLATVTVCLSLTAKRLASKNCVVKNLEAVETLGSTSVIC 384

  Fly   393 SDKTGTLTQNRMTVAHMWFDNQIIEADTTEDQSGVQYDRTSPGFKALSRIATLCNRAEFKGGQDG 457
            ||||||||||||||:|:||||.|..|||||||||..:|::|..::||.|:.||||||.||.|||.
  Rat   385 SDKTGTLTQNRMTVSHLWFDNHIHTADTTEDQSGQTFDQSSETWRALCRVLTLCNRAAFKSGQDA 449

  Fly   458 VPILKKEVSGDASEAALLKCMELALGDVMNIRKRNKKIAEVPFNSTNKYQVSIHETEDTNDPRYL 522
            ||:.|:.|.|||||.||||..||.||:.|..|.|..|:.|:|||||||:|:|||..||..|||:|
  Rat   450 VPVPKRIVIGDASETALLKFSELTLGNAMGYRDRFPKVCEIPFNSTNKFQLSIHTLEDPRDPRHL 514

  Fly   523 LVMKGAPERILERCSTIFINGKEKVLDEEMKEAFNNAYMELGGLGERVLGFCDFMLPSDKYPNGF 587
            |||||||||:|||||:|.|.|:|..|||:.:|||..||:.||||||||||||...|....||.|:
  Rat   515 LVMKGAPERVLERCSSILIKGQELPLDEQWREAFQTAYLSLGGLGERVLGFCQLYLNEKDYPPGY 579

  Fly   588 KFNTDDINFPIDNLRFVGLMSMIDPPRAAVPDAVAKCRSAGIKVIMVTGDHPITAKAIAKSVGII 652
            .|:.:.:|||...|.|.||:||||||||.|||||.|||:|||:||||||||||||||||.|||||
  Rat   580 TFDVEAMNFPSSGLCFAGLVSMIDPPRATVPDAVLKCRTAGIRVIMVTGDHPITAKAIAASVGII 644

  Fly   653 SEGNETVEDIAQRLNIPVSEVNPREAKAAVVHGAELRDVSSDQLDEILRYHTEIVFARTSPQQKL 717
            |||:|||||||.||.:||.:||.::|:|.|::|.:|:|:...:|.|.||.|.|:|||||||||||
  Rat   645 SEGSETVEDIAARLRMPVDQVNKKDARACVINGMQLKDMDPSELVEALRTHPEMVFARTSPQQKL 709

  Fly   718 IIVEGCQRMGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEE 782
            :|||.|||:||||||||||||||||||||||||||||||||.:|.|||||||||||||||||||:
  Rat   710 VIVESCQRLGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVEQ 774

  Fly   783 GRLIFDNLKKSIAYTLTSNIPEISPFLAFILCDIPLPLGTVTILCIDLGTDMVPAISLAYEHAEA 847
            |||||||||||||||||.||||::|:|.:|...:|||||.:|||.|:|.||:.|::|||||.||:
  Rat   775 GRLIFDNLKKSIAYTLTKNIPELTPYLIYITVSVPLPLGCITILFIELCTDIFPSVSLAYEKAES 839

  Fly   848 DIMKRPPRDPFNDKLVNSRLISMAYGQIGMIQAAAGFFVYFVIMAENGFLPKKLFGIRKMWDSKA 912
            |||...||:|..|:|||..|.:.:|.|||.||:.|||..||..||:.|:.|....|:|..|:...
  Rat   840 DIMHLRPRNPRRDRLVNEPLAAYSYFQIGAIQSFAGFADYFTAMAQEGWFPLLCVGLRPQWEDHH 904

  Fly   913 VNDLTDSYGQEWTYRDRKTLEYTCHTAFFISIVVVQWADLIICKTRRNSIFQQG-MRNWALNFGL 976
            :.||.||||||||:..|...:|||:|.|||||.:.|.||::|.||||.|.|||| .||..|...:
  Rat   905 LQDLQDSYGQEWTFGQRLYQQYTCYTVFFISIEMCQIADVLIRKTRRLSAFQQGFFRNRILVIAI 969

  Fly   977 VFETVLAAFLSYCPGMEKGLRMYPLKLVWWFPAIPFALAIFIYDETRRFYLRRNPGGWLEQETYY 1041
            ||:..:..||.|||||.......|::..||...:||.|.||:|||.|:..:|..||.|.:||.||
  Rat   970 VFQVCIGCFLCYCPGMPNIFNFMPIRFQWWLVPMPFGLLIFVYDEIRKLGVRCCPGSWWDQELYY 1034

  Fly  1042  1041
              Rat  1035  1034

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atpalpha	NP_732572.1	ATPase-IIC_X-K	45..1041	CDD:273445	616/996 (62%)
Atp4a	NP_036641.1	H-K_ATPase_N	2..>27	CDD:312544	7/31 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	15..40		6/31 (19%)
		ATPase-IIC_X-K	42..1034	CDD:273445	613/991 (62%)