Protein Alignment Atpalpha and Atp2c1

DIOPT Version :9

• Sequence 1: NP_732572.1
• Gene: Atpalpha / 48971
• FlyBaseID: FBgn0002921
• Length: 1041
• Species: Drosophila melanogaster
• Sequence 2: NP_001240760.1
• Gene: Atp2c1 / 235574
• MGIID: 1889008
• Length: 952
• Species: Mus musculus
• Alignment Length: 976
• Identity: 285/976 - (29%)
• Similarity: 458/976 - (46%)
• Gaps: 162/976 - (16%)

  Fly    63 KISPEELYQRFQTHPENGLSHAKAKENLERDGPNALTPPKQTPEWVKFCKNLFGGFAMLLWIGAI 127
            :::..|:....|...:|||:.::........|.|.....:..|.|.|:.........|||...|:
Mouse    62 ELAVSEVAGLLQADLQNGLNKSEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLLLASAV 126

  Fly   128 LCFVAYSIQASTSEEPADDNLYLGIVLSAVVIVTGIFSYYQESKSSKIMESFKNMVPQFATVIRE 192
            :..:......:.|           |.::.|::||  .::.||.:|.|.:|....:||.....:||
Mouse   127 ISILMRQFDDAVS-----------ITVAIVIVVT--VAFVQEYRSEKSLEELSKLVPPECHCVRE 178

  Fly   193 GEKLTLRAEDLVLGDVVEVKFGDRIPADIRIIEARNFKVDNSSLTGESEPQSRGAEFTHENP--- 254
            |:.....|.|||.||.|.:..|||:|||:|:.||.:..||.||||||:.|.|:   .|...|
Mouse   179 GKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSVDESSLTGETAPCSK---VTAPQPAAN 240

  Fly   255 ---LETKNLAFFSTNAVEGTAKGVVISCGDHTVMGRIAGLASGLDTGETP-------IAKEIHHF 309
               ....|:||..|....|.|||:||..|:::..|.:..:....:..:||       :.|::..:
Mouse   241 GDLASRSNIAFMGTLVRCGKAKGIVIGTGENSEFGEVFKMMQAEEAPKTPLQKSMDLLGKQLSFY 305

  Fly   310 IHLITGVAVFLGVTFFVIAFILGYHWLDAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMASKNC 374
            ...|.|:.:.:|       ::||...|:.....:.:.||.:||||...|||.|.|...||..|..
Mouse   306 SFGIIGIIMLVG-------WLLGKDILEMFTISVSLAVAAIPEGLPIVVTVTLALGVMRMVKKRA 363

  Fly   375 LVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIIEADTTEDQSGVQYDRTSP----- 434
            :||.|..|||||..:.||||||||||:|.|||.|: ..:..:.|:.|    ||.|::...
Mouse   364 IVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHI-LTSDGLHAEVT----GVGYNQFGEVIVDG 423

  Fly   435 ----GF--KALSRI---ATLCNRAEFKGGQDGVPILKKEVSGDASEAALLK-CMELALGDVMN-- 487
                ||  .|:|||   ..:||        |.| |....:.|..:|.||:. .|::.|..:..
Mouse   424 DVVHGFYNPAVSRIVEAGCVCN--------DAV-IRNNTLMGKPTEGALIALAMKMGLDGLQQDY 479

  Fly   488 IRKRNKKIAEVPFNSTNKYQV--SIHETEDTNDPRYLLVMKGAPERILERCSTIFINGKEKVLDE 550
            |||     ||.||:|..|:..  .:|.|:  .|...:..||||.|::::.|:|....|:...|.:
Mouse   480 IRK-----AEYPFSSEQKWMAVKCVHRTQ--QDRPEICFMKGAYEQVIKYCTTYNSKGQTLALTQ 537

  Fly   551 EMKEAFNNAYMELGGLGERVLGFCDFMLPSDKYPNGFKFNTDDINFPIDNLRFVGLMSMIDPPRA 615
            :.::.:......:|..|.|||....                   ...:..|.|:||:.:|||||.
Mouse   538 QQRDLYQQEKARMGSAGLRVLALAS-------------------GPELGQLTFLGLVGIIDPPRT 583

  Fly   616 AVPDAVAKCRSAGIKVIMVTGDHPITAKAIAKSVGIISEGNETVEDIAQRLNIPVSEVNPREAKA 680
            .|.:||....::|:.:.|:|||...||.|||..:|:.|:.:::|.
Mouse   584 GVKEAVTTLIASGVSIKMITGDSQETAIAIASRLGLYSKTSQSVS-------------------- 628

  Fly   681 AVVHGAELRDVSSDQLDEILRYHTEIVFARTSPQQKLIIVEGCQRMGAIVAVTGDGVNDSPALKK 745
                |.|:..:....|.:|:  ....||.|.||:.|:.|::..|:.||:||:|||||||:.|||.
Mouse   629 ----GEEVDTMEVQHLSQIV--PKVAVFYRASPRHKMKIIKSLQKNGAVVAMTGDGVNDAVALKA 687

  Fly   746 ADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEISPFLA 810
            ||||||||..|:||.|:||||||:||:|.:|::.:|||:.|::|:|..:.:.|:::|..::....
Mouse   688 ADIGVAMGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISL 752

  Fly   811 FILCDIPLPLGTVTILCIDLGTDMVPAISLAYEHAEADIMKRPPRDPFNDKLVNSRLISMAYGQI 875
            ..|.:.|.||..:.||.|::..|..||.||..|..:.|::::|||: :.|.::...||....  :
Mouse   753 ATLMNFPNPLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRN-WKDSILTKNLILKIL--V 814

  Fly   876 GMIQAAAG-FFVYFVIMAENGFLPKKLFGIRKMWDSKAVNDLTDSYGQEWTYRDRKTLEYTCHTA 939
            ..|....| .||::..:.:|...|                            || .|:.:||...
Mouse   815 SSIIIVCGTLFVFWRELRDNVITP----------------------------RD-TTMTFTCFVF 850

  Fly   940 FFISIVVVQWADLIICKTRRNSIFQQGMRNWALNFGLVFETVLAAFL-SYCPGMEKGLRMYPLKL 1003
            |       ...:.:..:::..|:|:.|:.:..:....|..:::...| .|.|.::|..:...|.:
Mouse   851 F-------DMFNALSSRSQTKSVFEIGLCSNKMFCYAVLGSIMGQLLVIYFPPLQKVFQTESLSI 908

  Fly  1004 V 1004
            :
Mouse   909 L 909

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atpalpha	NP_732572.1	ATPase-IIC_X-K	45..1041	CDD:273445	285/976 (29%)
		Cation_ATPase_N	58..132	CDD:214842	14/68 (21%)
		E1-E2_ATPase	152..383	CDD:278548	80/243 (33%)
		Cation_ATPase	445..539	CDD:289987	29/98 (30%)
		COG4087	<695..770	CDD:226572	42/74 (57%)
		Cation_ATPase_C	817..1025	CDD:279079	40/190 (21%)
Atp2c1	NP_001240760.1	ATPase-IIA2_Ca	57..936	CDD:130585	285/976 (29%)
		Cation_ATPase_N	60..128	CDD:279080	14/65 (22%)
		E1-E2_ATPase	152..372	CDD:278548	76/229 (33%)
		Cation_ATPase	443..526	CDD:289987	29/98 (30%)
		COG4087	589..712	CDD:226572	58/148 (39%)
		Cation_ATPase_C	759..931	CDD:279079	40/190 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53587
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920