DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Atpalpha and CG45063

DIOPT Version :9

Sequence 1:	NP_732572.1	Gene:	Atpalpha / 48971	FlyBaseID:	FBgn0002921	Length:	1041	Species:	Drosophila melanogaster
Sequence 2:	NP_001286728.1	Gene:	CG45063 / 19835490	FlyBaseID:	FBgn0266433	Length:	252	Species:	Drosophila melanogaster

Alignment Length:	246	Identity:	71/246 - (28%)
Similarity:	118/246 - (47%)	Gaps:	33/246 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 KSRRKMPAKVNKKENLDDLKQELDIDFHKISP-------EELYQRFQTHPENGLSHAKAKENLER 92
            :||||   |..::|:|...:.||.:::  .||       .||..|.:.:...||:...|...|.|
  Fly    17 RSRRK---KKEERESLQQTENELWLEY--FSPYLHIWPFHELCARLEANVSQGLTSEAAGRKLAR 76

  Fly    93 DGPNALTPPK--QTPEWVKFCKNLFGGFAMLLWIGAILCFVAYSIQASTSEEPADDN-------L 148
            :|.|.|..|.  :...|: |.|:.|....:::.:.:|..|..|.:.|:.:    .||       |
  Fly    77 NGKNVLPLPTKLELRPWI-FLKSCFSILGIIILLSSIASFAMYYLFATKT----PDNGKVDPEFL 136

  Fly   149 YLGIVLSAVVIVTGIFSYYQESKSSKIMESFKNMVPQFATVIREGEKLTLRAEDLVLGDVVEVKF 213
            ..||:|.....:.|:....|......::.:|..::|.:.||||:|||..:|.:|||.||.:.:|:
  Fly   137 VAGIILLVTFFLAGLTVQMQGDDDEDMLIAFDELMPMYCTVIRDGEKEVIRTQDLVPGDTLPIKY 201

  Fly   214 GDRIPADIRIIEARNFKVDNSSLTGESEPQSRGAEFTHENPLETKNLAFFS 264
            |.|:|||:|.......:::|.:|||.|:|.       |..||..:....:|
  Fly   202 GQRLPADMRFFSTTGLELNNVALTGHSKPM-------HITPLANEGRQRYS 245

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Atpalpha	NP_732572.1	ATPase-IIC_X-K	45..1041	CDD:273445	66/236 (28%)
		Cation_ATPase_N	58..132	CDD:214842	20/82 (24%)
		E1-E2_ATPase	152..383	CDD:278548	36/113 (32%)
		Cation_ATPase	445..539	CDD:289987
		COG4087	<695..770	CDD:226572
		Cation_ATPase_C	817..1025	CDD:279079
CG45063	NP_001286728.1	Cation_ATPase_N	46..117	CDD:214842	18/71 (25%)
CG45063	NP_001286728.1	E1-E2_ATPase	140..>230	CDD:278548	31/89 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S851
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.860