Protein Alignment Atpalpha and mca-1

DIOPT Version :9

• Sequence 1: NP_732572.1
• Gene: Atpalpha / 48971
• FlyBaseID: FBgn0002921
• Length: 1041
• Species: Drosophila melanogaster
• Sequence 2: NP_501709.2
• Gene: mca-1 / 177795
• WormBaseID: WBGene00003151
• Length: 1252
• Species: Caenorhabditis elegans
• Alignment Length: 993
• Identity: 281/993 - (28%)
• Similarity: 443/993 - (44%)
• Gaps: 234/993 - (23%)

  Fly    67 EELYQRFQTHPENGLSHAKAKENLERD--GPNALTPPKQTPEWVKF----CKN------LFGGFA 119
            |.|.::.:|....||:..:|..:..|.  |.|.: ||.::..:|:.    ||:      :..||.
 Worm    70 EGLCKKLKTDSLVGLNGEQADLDRRRHVYGANTI-PPAKSKGFVRLVLDACKDPTLVILVLSGFI 133

  Fly   120 ML-----------------LWIGAILCFVAYSIQASTSEEPAD-------DNLYLGIVLSAVVIV 160
            .|                 |........:|.....||:|.|::       :.:.:.:.:..||:|
 Worm   134 NLALSFYEPTSAAEDATQHLVNATTAAILANGTFMSTTEAPSEGHGTAWIEGVAILLCVIVVVLV 198

  Fly   161 TGIFSYYQESKSSKIMESFKNMVPQFATVIREGEKLTLRAEDLVLGDVVEVKFGDRIPADIRIIE 225
            |.:..|.:|.:...:.|..:  ..|..:|||.||.:.:...|||:||:..||:||.:|||..:|:
 Worm   199 TAVNDYSKERQFRSLQEKIE--TGQKFSVIRNGEAIDVPVSDLVVGDIARVKYGDLLPADGFLIQ 261

  Fly   226 ARNFKVDNSSLTGESEPQSRGAEFTH-ENPLETKNLAFFSTNAVEGTAKGVVISCGDHTVMGRI- 288
            :.:.|:|.|||||||:         | :..:|:..:....|.|:||:.|.::.:.|.::..|.|
 Worm   262 SNDLKIDESSLTGESD---------HIKKSIESDPVLLSGTYAMEGSGKMLITAVGVNSQTGIIM 317

  Fly   289 -------AGLA------------------------------SGLD--TGETPIAKEIHHFIHLIT 314
                   ||:.                              ||.|  |.::.:..::......|
 Worm   318 TLLGAGKAGIGDDDSTSTSSSSSSSSSSSGSSSNGSSDSSKSGDDDLTAKSVLQAKLSKLALQI- 381

  Fly   315 GVAVFLGVTFFVIAFIL---------------GYHWLDAVIFL------IGIIVANVPEGLLATV 358
               ::.|.|..:||.|:               .:..:|..:|:      :.|:|.::||||...:
 Worm   382 ---IYCGTTIAIIALIVLVTRFCLDHYVFEKNEFSLVDIQMFVKFFIIAVTILVISIPEGLPLAI 443

  Fly   359 TVCLTLTAKRMASKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIIEADTTED 423
            .:.||.:.::|...|.||::|:|.||:|:.::||||||||||.|||||...:     |..:....
 Worm   444 ALALTYSVRKMMHDNNLVRHLDACETMGNATSICSDKTGTLTTNRMTVVQSY-----INGNHYTS 503

  Fly   424 QSGVQYDRTSPGFKALSRIATLCNRAEFKGGQDGVPILKKEVS---------------------- 466
            |....:....||...                    |||.:.:|
 Worm   504 QEAQPHGANLPGSTG--------------------PILMEAISVNCAYNSMIVEPTKAGEQIQQL 548

  Fly   467 GDASEAALLKCMELALGDVMNIRKR--NKKIAEV-PFNSTNKYQVS-IHETEDTNDPRYLLVMKG 527
            |:.:|..||..:....||...|||:  ...:.:| .|||:.|..:: :...|:..:..|.:..||
 Worm   549 GNKTECGLLGFVNRLGGDYAAIRKKFPEHDLTKVYTFNSSRKCMMTVVPYAENGQNIGYRVYCKG 613

  Fly   528 APERILERCS-TIFINGK-EKVLDEEMKEAFNNAYMELGGLGERVL----------GFCDFMLPS 580
            |.|.:|.||: .|..:|| .::..:.:||..:....|:...|.|.:          |..|.....
 Worm   614 ASEIVLGRCTYLIGSDGKPHQLTGDRLKEITSTIIHEMANSGLRTICVAYKTIIKKGTRDVEKTE 678

  Fly   581 DKYPNGFKFNTDDINFPIDNLRFVGLMSMIDPPRAAVPDAVAKCRSAGIKVIMVTGDHPITAKAI 645
            .::......:.||.:....|...:.:..:.||.|..||.|::||:.|||.|.|||||:.:||:||
 Worm   679 IEFAEDSDIDWDDEDAMYQNFTGIAICGIQDPVRPEVPVAISKCKKAGITVRMVTGDNIMTARAI 743

  Fly   646 AKSVGIISEGNETVEDIAQRLNIPVSEVNPREAKAAVVHGAELRD----VSSDQLDEI---LRYH 703
            |.|..|:..|    ||.   |.:...|.|.|           :||    ||..:||||   ||
 Worm   744 AMSCKILEPG----EDF---LALEGKEFNER-----------IRDENGKVSQAKLDEIWPRLR-- 788

  Fly   704 TEIVFARTSPQQKLIIVEGC-------QRMGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSK 761
               |.||..|..|..:|:|.       ||  .||||||||.||.|||||||:|.||||||:||:|
 Worm   789 ---VLARAQPADKYTLVKGIIDSKATPQR--EIVAVTGDGTNDGPALKKADVGFAMGIAGTDVAK 848

  Fly   762 QAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEISPFLAFI----LCDIPLPLGT 822
            :|:|:||.||||.|||..|..||.::|::.|.:.:.||.|:  ::...||:    :.|.||.  .
 Worm   849 EASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNV--VAVITAFVGAVTVSDSPLK--A 909

  Fly   823 VTILCIDLGTDMVPAISLAYEHAEADIMKRPPRDPFNDKLVNSRLISMAYGQIGMIQAAAGFFVY 887
            |.:|.|:|..|.:.:::||.|....::::   |.|:..|   ..|||....:..:..|.....:.
 Worm   910 VHMLWINLIMDTLASLALATEQPTDELLE---RKPYGRK---KSLISRTMVKNILCHALYQLIII 968

  Fly   888 FVIMAENGFLPKKLFGIR 905
            |||.    |....:|||:
 Worm   969 FVIF----FYGDTIFGIK 982

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atpalpha	NP_732572.1	ATPase-IIC_X-K	45..1041	CDD:273445	281/993 (28%)
		Cation_ATPase_N	58..132	CDD:214842	18/93 (19%)
		E1-E2_ATPase	152..383	CDD:278548	73/292 (25%)
		Cation_ATPase	445..539	CDD:289987	27/120 (23%)
		COG4087	<695..770	CDD:226572	46/84 (55%)
		Cation_ATPase_C	817..1025	CDD:279079	24/89 (27%)
mca-1	NP_501709.2	ATPase-IIB_Ca	46..1087	CDD:273668	281/993 (28%)
		Cation_ATPase_N	66..133	CDD:279080	15/63 (24%)
		E1-E2_ATPase	225..468	CDD:278548	65/255 (25%)
		Cation_ATPase	532..624	CDD:289987	23/91 (25%)
		Cation_ATPase_C	905..1083	CDD:279079	24/90 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53587
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920