Protein Alignment Atpalpha and catp-1

DIOPT Version :9

• Sequence 1: NP_732572.1
• Gene: Atpalpha / 48971
• FlyBaseID: FBgn0002921
• Length: 1041
• Species: Drosophila melanogaster
• Sequence 2: NP_001122528.1
• Gene: catp-1 / 173307
• WormBaseID: WBGene00013672
• Length: 1121
• Species: Caenorhabditis elegans
• Alignment Length: 1144
• Identity: 365/1144 - (31%)
• Similarity: 579/1144 - (50%)
• Gaps: 164/1144 - (14%)

  Fly     9 HGRADSYRVA--TVIATDDDNRTADGQYKSRRKMPAKVNKKENLDDLKQELDIDFHKISPE---E 68
            :|..|.:..|  ::.::..||.....:.|.:|....:.:....|.|:.:...:: |.:|.:   :
 Worm    11 NGVVDIHESAGTSICSSSADNTVTKEKAKRKRAEKEETDHGMTLHDIIKTSFVE-HTLSVDQIRD 74

  Fly    69 LYQRFQTHPE-----NGLSHAKAKENLERDGPNALTPPKQTPEWVKFCKNLFG-GFAMLLWIGAI 127
            ||......|:     :||...:||:.|:..|.|.:..| |.|...:|..:.|. .|.:||...|:
 Worm    75 LYPDSYVFPQCAERSDGLHSDEAKKRLKDGGLNQIDRP-QEPSLSRFFLSQFHFKFWILLLGAAV 138

  Fly   128 LCFVAYSI-QASTSEEPADDNLYLGIVLSAVVIVTGIFSYYQESKSSKIMESFKNMVPQFATVIR 191
            |..:.|.| .|....||.  |||..|:|.|||:..|:.||:|::|:.|:::..::|:|..:.|||
 Worm   139 LSVMTYFIHMARGFNEPL--NLYCAIILIAVVVFMGMLSYWQQAKAKKVLQENRDMMPVMSYVIR 201

  Fly   192 EGEKLTLRAEDLVLGDVVEVKFGDRIPADIRIIEARNFKVDNSSLTGESEPQSRGAEFTHEN--P 254
            :.|:..::|:::|:||:|.::.|.:||||:||::|....:::..:||...||...::....|  .
 Worm   202 DCEEQEIKADEIVVGDLVYLRAGYKIPADMRILQANCLMIESHDVTGHRMPQEYKSDPVQANVSV 266

  Fly   255 LETKNLAFFSTNAVEGTAKGVVISCGDHTVMGRIAGLASGLDTGETPIAKEIHHFIHLITGVAVF 319
            .:..|:||..:...||...|:||..|..||:|.:|.....:......:..|:.:|...|:.||:.
 Worm   267 FDACNVAFMGSYCTEGEGIGIVIRTGKFTVLGALANQHHHIPPPSGRLQTELQNFSTFISIVAIS 331

  Fly   320 LG-VTFFVIAFILGY-HWLDAVIFLIG---IIVANVPEGLLATVTVCLTLTAKRMASKNCLVKNL 379
            :. |.||:..|:..: :.||.  |::|   |||||||:||.|||...|.:.|:|||.||.|:|.|
 Worm   332 MATVVFFIGCFVARFENVLDH--FIVGFVVIIVANVPQGLPATVMSQLRIIARRMAQKNILIKKL 394

  Fly   380 EAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIIEADTTEDQSGVQYDRTSPGFKALS---- 440
            |.::.||:.:.||:||:||||.|:|.|..:||:::::        :|...|...|..:.:.
 Worm   395 ELIDELGAATVICADKSGTLTMNQMVVTDLWFNSRLV--------TGQAVDLKHPHLRVMKASMK 451

  Fly   441 -------------RIATLCNRAEFK---------------------------------------- 452
                         .:.::||..:|:
 Worm   452 CPERLEEPLPDILTVMSVCNNGQFEHVRRGMRRVSTMRAMQKSASEAMLSAHMKKKFTIVDTRTG 516

  Fly   453 --GGQDG---------------------VPILKKEVSGDASEAALLKCMELALGDVMNIRKRNKK 494
              .||.|                     |...|.::.|..|:.||:|.:||: ..|..||:|.:.
 Worm   517 QVSGQAGGVMKEADQISETEPTELGKKRVKPKKNDIFGVPSDVALIKYVELS-ASVEGIRQRYQT 580

  Fly   495 IAEVPFNSTNKYQVSIHE---------TEDTNDP-----RYLLVMKGAPERILERCSTIFINGKE 545
            :.|:||||..:.||.:..         :|..::|     |:::..|||||.||.:||. :..|||
 Worm   581 VFEIPFNSIRRCQVVVARYLASDFPMTSELVDNPEEGQSRFMIFTKGAPEVILGKCSN-YRQGKE 644

  Fly   546 -KVLDEEMKEAFNNAYMELGGLGERVLGFCDFMLPSDKYPNGFKFNTDDINFPIDNLRFVGLMSM 609
             |.:||..:.....|:..||..|.||:.|......:|   :..||...:.|   .:|.|:|:.::
 Worm   645 LKTIDETYRTECQAAWEMLGNEGRRVIAFAQKSFNAD---DSTKFTGQEYN---GDLVFLGMAAI 703

  Fly   610 IDPPRAAVPDAVAKCRSAGIKVIMVTGDHPITAKAIAKSVGIISEGNETVEDIAQRLNIPVSEVN 674
            :||||.....|:.:|:.||:||.|:|||||.||.|||:.:|:|  |:.|      .||    :|.
 Worm   704 MDPPRPETAAAIEQCKMAGVKVFMITGDHPTTATAIARQIGLI--GSST------NLN----DVE 756

  Fly   675 PREAKAAVVHGAELRDVSSDQLDEILRYHTEIVFARTSPQQKLIIVEGCQRMGAIVAVTGDGVND 739
            ..:...|||.|.:|::......:.:|:.| .||||||:.:|||.||:..||.|..|||||.||:|
 Worm   757 KPQNSWAVVTGDQLKNYKKSDWNLLLKNH-NIVFARTNTEQKLEIVQEVQRRGETVAVTGGGVDD 820

  Fly   740 SPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPE 804
            :|.|..|::|:|||.:|||::||.||::||||||||||.|:|||||:||||:.|:|||.....||
 Worm   821 TPVLAHANVGIAMGQSGSDIAKQTADIVLLDDNFASIVMGIEEGRLLFDNLRLSLAYTFAHLWPE 885

  Fly   805 ISPFLAFILCDIPLPLGTVTILCIDLGTDMVPAISLAYEHAEADIMKRPPRDPFNDKLVNSRLIS 869
            :.|.:...:..:|..|..:.||.:||.::|.||||||||..|.|||..|||.. ..:|::..|:.
 Worm   886 VFPIMMSFMLGLPHGLSPLQILSVDLASEMPPAISLAYEQPENDIMHTPPRSR-TARLLSKSLLV 949

  Fly   870 MAY-----G-QIGMIQAAAGFFVYFVIMAENGFLPKKLFGIRKMWDSKAVNDLTDSYGQEWTYRD 928
            .||     | .||.|.|....:.|     .|..:...||.....|...|.| .|.|.|..:..:.
 Worm   950 YAYILAGFGITIGCIAAYLSVYWY-----HNIPISDILFTAEHHWKIGAKN-FTTSQGLTFGEQQ 1008

  Fly   929 RKTLEYTCHTAFFISIVVVQWADLIICKTRRNSIFQQGMRNWALNFGLVFETVLAAFLSYCPGME 993
            :..::.....|:.|::|:.|...|..|.|||.|:|:.|:.|....|.::.|.:|.....|.|..:
 Worm  1009 QLFIKGQAAAAWQITLVMSQVFHLYNCTTRRVSVFRHGLTNIVSVFAVIIEILLLFMFVYTPVFQ 1073

  Fly   994 KGLRMY-PLKLVWWFPAIPFALAIFIYDETRRFYLRRNP 1031
            ..:.:: |...||....| ..|.:..::|.|::::|..|
 Worm  1074 YIMDIHTPPAHVWAIAPI-VGLYLLAFNEMRKYFIRNFP 1111

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atpalpha	NP_732572.1	ATPase-IIC_X-K	45..1041	CDD:273445	358/1106 (32%)
		Cation_ATPase_N	58..132	CDD:214842	22/82 (27%)
		E1-E2_ATPase	152..383	CDD:278548	84/237 (35%)
		Cation_ATPase	445..539	CDD:289987	38/170 (22%)
		COG4087	<695..770	CDD:226572	39/74 (53%)
		Cation_ATPase_C	817..1025	CDD:279079	66/214 (31%)
catp-1	NP_001122528.1	HAD_like	91..1111	CDD:389748	350/1061 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D388324at2759
OrthoFinder	1	1.000	-	-		FOG0000283
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100215
Panther	1	1.100	-	-	O	PTHR43294
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920