Protein Alignment Atpalpha and pmr-1

DIOPT Version :9

• Sequence 1: NP_732572.1
• Gene: Atpalpha / 48971
• FlyBaseID: FBgn0002921
• Length: 1041
• Species: Drosophila melanogaster
• Sequence 2: NP_001021862.1
• Gene: pmr-1 / 173176
• WormBaseID: WBGene00004063
• Length: 978
• Species: Caenorhabditis elegans
• Alignment Length: 1077
• Identity: 289/1077 - (26%)
• Similarity: 488/1077 - (45%)
• Gaps: 194/1077 - (18%)

  Fly    11 RADSYRVATVIATDDDNRTADGQYKSRRKMPAKVNKKENLDDLKQELDID-------------FH 62
            |.......|..:|...|..|.....:...:.|:|:......|..:.:..|             .|
 Worm    26 RVQGNTTTTTTSTTSTNGIAQKHQPTTPLVKAEVSTNHISKDRSKSISKDDIMIETLTSEQAASH 90

  Fly    63 KISPEELYQRFQTHPENGLSHAKAKENLERDGPNALTPPKQTPEWVKFCKNLFGGFAMLLWIGAI 127
            ::.|  ...:.:|:.|.||:.|:|....:..|.|.....::.|.:.|:.:.......:||...|.
 Worm    91 EVVP--CTHQLRTNLEEGLTTAEATRRRQYHGYNEFDVGEEEPIYKKYLEQFQNPLILLLLASAF 153

  Fly   128 LCFVAYSIQASTSEEPADDNLYLGIVLSAVVIVTGIFSYYQESKSSKIMESFKNMVPQFATVIRE 192
            :..|.         :..||  .:.|.::.|::||  ..:.||.:|.|.:|....:||....|:|:
 Worm   154 VSIVM---------KQYDD--AISITVAVVIVVT--VGFVQEYRSEKTLEQLTKLVPPTCHVLRD 205

  Fly   193 GEKLTLRAEDLVLGDVVEVKFGDRIPADIRIIEARNFKVDNSSLTGESEPQSR------GAEFTH 251
            |::..:.|.:||.||:|.:..|||||:|:||.|:.:.::|.||||||:||:.:      .|..|.
 Worm   206 GKEAMMLARELVPGDIVLLNTGDRIPSDLRIAESFSLQIDESSLTGETEPKHKETRSVPAASATG 270

  Fly   252 ENPLETKNLAFFSTNAVEGTAKGVVISCGDHTVMGRIAGLASGLDTGETPIAKEIHHF-----IH 311
            .:......:||..|....|..:|:|||...::..|.:..:..|.::.:||:.|.:...     |:
 Worm   271 SDVEHLTCIAFMGTLVCAGRGRGIVISTAANSQFGEVVKMMMGEESPKTPLQKSMDDLGKQLSIY 335

  Fly   312 LITGVAVFLGVTFFVIAFILGYHWLDAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMASKNCLV 376
            ....:||     .|:|....|.:.:|.....:.:.||.:||||...|.|.|.:...|||.:..:|
 Worm   336 SFGVIAV-----IFLIGMFQGRNVVDMFTIGVSLAVAAIPEGLPIVVAVTLAIGVMRMAKRRAVV 395

  Fly   377 KNLEAVETLGSTSTICSDKTGTLTQNRMT----------VAHMWFDNQIIEADTTEDQSGVQYDR 431
            |.:.||||||..:.||||||||||:|.||          :|.:.......|....:.|....:..
 Worm   396 KKMPAVETLGCVTVICSDKTGTLTKNEMTAQAIATPEGKLAEITGIGYSAEGGVVQYQGEQVHQW 460

  Fly   432 TSPGFKALSRIATLCNRAEFKGGQDGVPILKKEVSGDASEAALLKCMELALGDVMNIRKRNKKIA 496
            |.|.|..:.....:||.|..:.         .::.|..:|.|::...:.|  .:..:|...|::.
 Worm   461 THPEFARIIEAGLVCNNATIEA---------DKLIGQPTEGAIVVLAKKA--QLEGVRSEYKRLR 514

  Fly   497 EVPFNSTNKYQ-VSIHETEDTNDPRYLLVMKGAPERILERCSTIF-INGKEKVLDEEMKEAFNNA 559
            |:||:|..|:. |...:....|    :..:|||.:|:|::|.|.: .:.:.|..|:..::.....
 Worm   515 EMPFSSDTKWMGVQCADAHGQN----VYFIKGALDRVLDQCGTYYSSDNQRKQCDQYSRQHILEI 575

  Fly   560 YMELGGLGERVLGFCDFMLPSDKYPNGFKFNTDDINFPIDNLRFVGLMSMIDPPRAAVPDAVAKC 624
            ..|||..|.||||...                   ...:.:|.|:|::.|:||||....||::..
 Worm   576 GKELGQKGLRVLGLAR-------------------GESMQSLMFLGMIGMMDPPRPGAADAISIV 621

  Fly   625 RSAGIKVIMVTGDHPITAKAIAKSVGIISEGNETVEDIAQRLNIPVSEVNPREAKAAVVHGAELR 689
            :::|:.|.::|||...||::|.:|:||:|..:                        :.:.|.::.
 Worm   622 KASGVDVKLITGDAMETAQSIGQSLGILSSSD------------------------SCLSGQQVD 662

  Fly   690 DVSSDQLDEILRYHTEIVFARTSPQQKLIIVEGCQRMGAIVAVTGDGVNDSPALKKADIGVAMGI 754
            .:|...|:.::|..|  ||.|.||:.||.||:..|.:|.:||:|||||||:.||||||||||||:
 Worm   663 QMSDHDLELVIRQVT--VFYRASPRHKLKIVKALQALGEVVAMTGDGVNDAVALKKADIGVAMGV 725

  Fly   755 AGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEISPFLAFILCDIPLP 819
            .|:||.|:||||||.||:|:::...:|||:.|:.|:...:.:.|::::..:|...|..:.....|
 Worm   726 CGTDVCKEAADMILCDDDFSTMTAAIEEGKAIYHNITNFVRFQLSTSVAALSLIAASTMFKFDNP 790

  Fly   820 LGTVTILCIDLGTDMVPAISLAYEHAEADIMKRPPRDP----FNDKLVNSRLISMAYGQIGMIQA 880
            |..:.||.|::..|..||.||..|..:.||:::.||:.    ...||:...|.|.|...:|.:..
 Worm   791 LNAMQILWINIIMDGPPAQSLGVEPVDDDIIRQRPRNTKQPMLTGKLIADILASAAIIVVGTLSV 855

  Fly   881 AAGFFVYFVIMAENGFLPKKLFGIRKMWDSKAVNDLTDSYGQEWTYRDRKTLEYTCHTAFFISIV 945
                 .|..:.|:|...|                            || .|:.:||...|.:
 Worm   856 -----FYKEMSADNKVTP----------------------------RD-TTMTFTCFVLFDM--- 883

  Fly   946 VVQWADLIICKTRRNSIFQQGMRNWALNFGLVFETVLAAFLSYCPGMEKGLRMYPLKLVWWFP-- 1008
               | :.:.|::.|..|:|.|:|.     ..:|...::|.|           :..|.:::|.|
 Worm   884 ---W-NALSCRSSRKMIWQIGLRR-----NRMFSLAVSASL-----------ICQLLVIYWAPLQ 928

  Fly  1009 ---------------AIPFALAIFIYDETRRFYLRRN 1030
                           ......::||::|||:::..|:
 Worm   929 HIFQTEALSLFDLIFLTTITSSVFIFNETRKYFSLRS 965

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atpalpha	NP_732572.1	ATPase-IIC_X-K	45..1041	CDD:273445	282/1043 (27%)
		Cation_ATPase_N	58..132	CDD:214842	16/86 (19%)
		E1-E2_ATPase	152..383	CDD:278548	75/241 (31%)
		Cation_ATPase	445..539	CDD:289987	22/94 (23%)
		COG4087	<695..770	CDD:226572	45/74 (61%)
		Cation_ATPase_C	817..1025	CDD:279079	49/228 (21%)
pmr-1	NP_001021862.1	ATPase-IIA2_Ca	81..967	CDD:130585	280/1022 (27%)
		Cation_ATPase_N	98..155	CDD:279080	13/56 (23%)
		E1-E2_ATPase	181..402	CDD:278548	71/225 (32%)
		Cation_ATPase	474..554	CDD:289987	22/94 (23%)
		HAD_like	610..723	CDD:119389	50/138 (36%)
		Cation_ATPase_C	790..961	CDD:279079	49/227 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53587
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920