Protein Alignment Atpalpha and atp2c1

DIOPT Version :9

• Sequence 1: NP_732572.1
• Gene: Atpalpha / 48971
• FlyBaseID: FBgn0002921
• Length: 1041
• Species: Drosophila melanogaster
• Sequence 2: XP_002937789.2
• Gene: atp2c1 / 100487845
• XenbaseID: XB-GENE-968174
• Length: 961
• Species: Xenopus tropicalis
• Alignment Length: 956
• Identity: 282/956 - (29%)
• Similarity: 450/956 - (47%)
• Gaps: 171/956 - (17%)

  Fly    78 ENGLSHAKAKENLERDGPNALTPPKQTPEWVKFCKNLFGGFAMLLWIGAILCFVAYSIQASTSEE 142
            ::||::.:........|.|.....:..|.|.|:.:.......|||...|::..:......:.|
 Frog    87 QSGLNNPEVCHRRAAHGWNEFDISEGEPLWKKYIEQFKNPLLMLLLASAVISILMQQFDDAVS-- 149

  Fly   143 PADDNLYLGIVLSAVVIVTGIFSYYQESKSSKIMESFKNMVPQFATVIREGEKLTLRAEDLVLGD 207
                     |.::.:::||  .::.||.:|.|.:|....:||.....||||......|.|||.||
 Frog   150 ---------ITVAILIVVT--VAFVQEYRSEKSLEELSKLVPPECHCIREGRMEHTLARDLVPGD 203

  Fly   208 VVEVKFGDRIPADIRIIEARNFKVDNSSLTGESEPQSRGAEFTHENPLET-------KNLAFFST 265
            .|.:..|||:|||:|:.||.:..||.||||||:.|   .|:.|...|..:       .|:||..|
 Frog   204 TVCLTVGDRVPADLRLFEAMDLSVDESSLTGETAP---CAKSTAPQPCASNGDLTSRSNIAFMGT 265

  Fly   266 NAVEGTAKGVVISCGDHTVMGRIAGLASGLDTGETP-------IAKEIHHFIHLITGVAVFLGVT 323
            ....|.|||:||..|:::..|.:..:....:..:||       :.|::..:...|.||.:.:|
 Frog   266 LVRCGKAKGIVIGTGENSEFGEVFKMMQAEEAPKTPLQKSMDILGKQLSLYSFGIIGVIMLVG-- 328

  Fly   324 FFVIAFILGYHWLDAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMASKNCLVKNLEAVETLGST 388
                 ::.|.|.||.....:.:.||.:||||...|||.|.|...||..|..:||.|..|||||..
 Frog   329 -----WLQGKHILDMFTIGVSLAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCC 388

  Fly   389 STICSDKTGTLTQNRMTVAHMWFDNQIIEADTTEDQSGVQYDR--------------TSPGFKAL 439
            :.||||||||||:|.|||.|: |.:..:.|:.|    ||.|:|              .:|....:
 Frog   389 NVICSDKTGTLTKNEMTVTHI-FTSDGLHAEVT----GVGYNRFGEVIHDGEIIHGFCNPSISKV 448

  Fly   440 SRIATLCNRAEFKGGQDGVPILKKEVSGDASEAALLKCMELALGDVMNIRKRNKKIAEVPFNSTN 504
            .....:||.||         |....:.|..:|.||: .:.:.:| :..:|....:.||.||:|..
 Frog   449 IEAGCVCNDAE---------IRNNTLMGKPTEGALI-ALSMKMG-LEALRHDYIRRAEYPFSSEQ 502

  Fly   505 KYQV--SIHETEDTNDPRYLLVMKGAPERILERCSTIFINGKEKVLDEEMKEAF--NNAYMELGG 565
            |:..  .:|.|:  .|...:..||||.|::::.|:|....|:...|.::.:|.:  ..|||...|
 Frog   503 KWMAVKCVHRTQ--QDKPEICFMKGAYEQVIKYCTTYNSKGQTFPLTQQQRELYLQETAYMGTAG 565

  Fly   566 LGERVLGFCDFMLPSDKYPNGFKFNTDDINFPIDNLRFVGLMSMIDPPRAAVPDAVAKCRSAGIK 630
            |  ||:....                   ...:..|.|:||:.||||||..|.:||:....:|:.
 Frog   566 L--RVIALAS-------------------GPELGQLTFLGLVGMIDPPRTGVKEAVSTLIRSGVA 609

  Fly   631 VIMVTGDHPITAKAIAKSVGIISEGNETV--EDI----AQRLNIPVSEVNPREAKAAVVHGAELR 689
            :.|:|||...||.|||..:|..|:|.:::  ||:    .|:|:..||:|:
 Frog   610 IKMITGDSQETAVAIASRLGFYSKGLQSLSGEDVDMMDIQQLSQMVSKVS--------------- 659

  Fly   690 DVSSDQLDEILRYHTEIVFARTSPQQKLIIVEGCQRMGAIVAVTGDGVNDSPALKKADIGVAMGI 754
                             ||.|.||:.||.||:..|.:||:||:|||||||:.|||.||||:|||.
 Frog   660 -----------------VFYRASPRHKLKIVKSLQNIGAVVAMTGDGVNDAVALKAADIGIAMGK 707

  Fly   755 AGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEISPFLAFILCDIPLP 819
            .|:||.|:||||||::|:|.:|::.:|||:.|::|:|..:.:.|:::|..::......|.:.|.|
 Frog   708 TGTDVCKEAADMILVEDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNP 772

  Fly   820 LGTVTILCIDLGTDMVPAISLAYEHAEADIMKRPPRDPFNDKLVNSRLISMAYGQIGMIQAAAGF 884
            |..:.||.|::..|..||.||..|..:.|::::|||:..:..|..:.::.:....|  |......
 Frog   773 LNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNLKDSILTKNLIVKILLSSI--IIVCGTL 835

  Fly   885 FVYFVIMAENGFLPKKLFGIRKMWDSKAVNDLTDSYGQEWTYRDRKTLEYTCHTAFFISIVVVQW 949
            ||::..:.:|...|                            || .|:.:||...|       ..
 Frog   836 FVFWRELRDNLITP----------------------------RD-TTMTFTCFVFF-------DM 864

  Fly   950 ADLIICKTRRNSIFQQGMRNWALNFGLVFETVLAAFL-SYCPGMEK 994
            .:.:..:::..|:|:.|:.:..:....|..:::...| .|.|.::|
 Frog   865 FNALSSRSQTKSVFEIGLCSNKMFCYAVLGSIMGQLLVIYFPPLQK 910

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atpalpha	NP_732572.1	ATPase-IIC_X-K	45..1041	CDD:273445	282/956 (29%)
		Cation_ATPase_N	58..132	CDD:214842	11/53 (21%)
		E1-E2_ATPase	152..383	CDD:278548	82/244 (34%)
		Cation_ATPase	445..539	CDD:289987	26/95 (27%)
		COG4087	<695..770	CDD:226572	41/74 (55%)
		Cation_ATPase_C	817..1025	CDD:279079	37/179 (21%)
atp2c1	XP_002937789.2	P-type_ATPase_SPCA	98..940	CDD:319779	280/945 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53587
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920