Protein Alignment Atpalpha and atp2b4

DIOPT Version :9

• Sequence 1: NP_732572.1
• Gene: Atpalpha / 48971
• FlyBaseID: FBgn0002921
• Length: 1041
• Species: Drosophila melanogaster
• Sequence 2: XP_002934276.2
• Gene: atp2b4 / 100487776
• XenbaseID: XB-GENE-960658
• Length: 1257
• Species: Xenopus tropicalis
• Alignment Length: 1148
• Identity: 302/1148 - (26%)
• Similarity: 478/1148 - (41%)
• Gaps: 338/1148 - (29%)

  Fly    69 LYQRFQTHPENGL--SHAKAKENLERDGPNALTPPKQTPEWVKFCKNLFGGFAMLLW-------- 123
            |.:|.:|.|..||  :.|..::..:..|.|.: |||:...           |..|:|
 Frog    56 LCRRLKTSPTEGLPGTAADLEKRRQTFGQNFI-PPKKPKT-----------FLQLVWEALQDVTL 108

  Fly   124 ----IGAILCFVAYSIQASTSEEPADDNLYLG---------------------IVLSAV-VIVTG 162
                |.||:     |:..|....|..:....|                     |:||.| |::..
 Frog   109 IILEIAAII-----SLGLSFYRPPGGETEGCGGAAAGAEDEGEAEAGWIEGAAILLSVVCVVLVT 168

  Fly   163 IFSYYQESKSSKIMESFKNMVPQFATVIREGEKLTLRAEDLVLGDVVEVKFGDRIPADIRIIEAR 227
            .|:.:.:.|..:.::|......:| ||:|..:.:.:...::|:||:.:||:||.:|.|...|:..
 Frog   169 AFNDWSKEKQFRGLQSRIEQEQKF-TVVRGSQVIQIPVAEMVVGDIAQVKYGDLLPTDGIFIQGN 232

  Fly   228 NFKVDNSSLTGESEPQSRGAEFTHENPLETKNLAFFSTNAVEGTAKGVVISCGDHTVMGRI---- 288
            :.|:|.|||||||:...:..:   ::|     :....|:.:||:.:.:|.:.|.::..|.|
 Frog   233 DLKIDESSLTGESDQVRKSVD---KDP-----MLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLL 289

  Fly   289 ---------------------------------------------------AGLASG-------- 294
                                                               |.|.:|
 Frog   290 GASEAEDEKKDKKGVKKEEGPQLQVGSTHPPSHPPAATDGAAGANAIDNANASLVNGKMQDGNVE 354

  Fly   295 -------------------LDTGE--------------------------TPIAKEIHHFIHLIT 314
                               |.:.|                          |.:|.:|.....:::
 Frog   355 SIQNKAKQQDGAAAMEMQPLKSAEGGDGDDKDKKKSNPHKKEKSVLQGKLTKLAVQIGKAGLVMS 419

  Fly   315 GVAVFLGVTFFVI-AFILG-YHWLD----------AVIFLIG--IIVANVPEGLLATVTVCLTLT 365
            .:.|.:.|.:|.| .|::. ..||.          ...|:||  ::|..|||||...||:.|..:
 Frog   420 AITVIILVLYFAIDTFVVNKRQWLPECTPIYIQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYS 484

  Fly   366 AKRMASKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIIEADTTEDQSGVQYD 430
            .|:|...|.||::|:|.||:|:.:.||||||||||.|||||...:..:  :......|..|:...
 Frog   485 VKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQAFVGD--VHYKEIPDPDGLPAK 547

  Fly   431 RTSPGFKALSRIATLCNR---AEFKGGQDGVPILKKEVSGDASEAALLKCMELALGDVMNIRK-- 490
            .......|::..:...::   ||..||      |.::| |:.:|..|       ||.|:::::
 Frog   548 TLDVLVHAIAINSAYTSKVLPAEKDGG------LPRQV-GNKTECGL-------LGFVLDLKRDY 598

  Fly   491 ---RNK----KIAEV-PFNSTNKYQVSIHETEDTNDPRYLLVMKGAPERILERCS-TIFINGKEK 546
               |||    |:.:| .|||..|...::.:.||.:   |.:..|||.|.:|::|| |:...|:.:
 Frog   599 QVVRNKIPEEKLYKVYTFNSVRKSMSTVVKLEDGS---YRMYSKGASEIVLKKCSRTLNEAGEPR 660

  Fly   547 VL-----DEEMKEAFNNAYMELGGLGERVLGFCDF-MLPSDKYPNGFKFNTDDINFPIDNLRFVG 605
            :.     |:.:|.....  |...||....:.:.|| |.|...:.     |.:||   :.:|..:.
 Frog   661 IFRPRDRDDMVKNVIEP--MACDGLRTICIAYRDFPMSPEPDWD-----NENDI---VTDLTCLA 715

  Fly   606 LMSMIDPPRAAVPDAVAKCRSAGIKVIMVTGDHPITAKAIAKSVGIISEGNETVEDIAQRLNIPV 670
            ::.:.||.|..||:|:.||:.|||.|.|||||:..||:|||...|||..|    ||.   |.|..
 Frog   716 VVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAIKCGIIHPG----EDF---LCIEG 773

  Fly   671 SEVNPREAKAAVVHGAELRDVSSDQLDEI---LRYHTEIVFARTSPQQKLIIVEGC-------QR 725
            .|.|.|...       |..::..:::|:|   ||     |.||:||..|..:|:|.       ||
 Frog   774 KEFNRRIRN-------EKGEIEQERIDKIWPKLR-----VLARSSPTDKHTLVKGIIDSTQVEQR 826

  Fly   726 MGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNL 790
            .  :|||||||.||.|||||||:|.||||||:||:|:|:|:||.||||.|||..|..||.::|::
 Frog   827 Q--VVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSI 889

  Fly   791 KKSIAYTLTSNIPEISPFLAF----ILCDIPLPLGTVTILCIDLGTDMVPAISLAYEHAEADIMK 851
            .|.:.:.||.|:  ::..:||    |..|.||.  .|.:|.::|..|...:::||.|.....::.
 Frog   890 SKFLQFQLTVNV--VAVIVAFTGACITQDSPLK--AVQMLWVNLIMDTFASLALATEPPTESLLL 950

  Fly   852 RPP---RDPFNDKLVNSRLISMAYGQIGMIQAAAGFFVYFV------------------------ 889
            |.|   ..|...:.:...::..|..|:.:|     |.:.||
 Frog   951 RKPYGRNKPLISRTMMKNILGHAVYQLTLI-----FTLLFVGEDLFNIDSGRNAPLHSPPSEHYT 1010

  Fly   890 ------IMAE--NGFLPKKLFGIRKMWDSKAVNDL--TDSYGQEWTYRDRKTLEYTCHTAFFISI 944
                  :|.:  |....:|:.|.|.::|....|.:  |...|                 .|.|.|
 Frog  1011 IIFNTFVMMQLFNEINARKIHGERNVFDGIFRNPIFCTIVLG-----------------TFAIQI 1058

  Fly   945 VVVQWADLIICKTRRNSIFQQGMRNWA--LNFG-LVFETVLAA 984
            |:||:..    |....|..|.....|.  |.|| ||:..|:.:
 Frog  1059 VIVQFGG----KPFSCSPLQLDQWMWCIFLGFGELVWGQVITS 1097

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atpalpha	NP_732572.1	ATPase-IIC_X-K	45..1041	CDD:273445	302/1148 (26%)
		Cation_ATPase_N	58..132	CDD:214842	18/76 (24%)
		E1-E2_ATPase	152..383	CDD:278548	73/353 (21%)
		Cation_ATPase	445..539	CDD:289987	31/107 (29%)
		COG4087	<695..770	CDD:226572	44/84 (52%)
		Cation_ATPase_C	817..1025	CDD:279079	43/208 (21%)
atp2b4	XP_002934276.2	ATPase-IIB_Ca	12..1101	CDD:273668	302/1148 (26%)
		ATP_Ca_trans_C	1140..1186	CDD:403580

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000