Protein Alignment Atpalpha and atp1a2

DIOPT Version :9

• Sequence 1: NP_732572.1
• Gene: Atpalpha / 48971
• FlyBaseID: FBgn0002921
• Length: 1041
• Species: Drosophila melanogaster
• Sequence 2: NP_001096439.1
• Gene: atp1a2 / 100125050
• XenbaseID: XB-GENE-6034696
• Length: 1020
• Species: Xenopus tropicalis
• Alignment Length: 1020
• Identity: 763/1020 - (74%)
• Similarity: 879/1020 - (86%)
• Gaps: 11/1020 - (1%)

  Fly    32 GQYKSRRKMPAKVN----------KKENLDDLKQELDIDFHKISPEELYQRFQTHPENGLSHAKA 86
            |:.:.|...||..|          |::.:|:||:|:.:|.||:|.||:.:::.|....||::|:|
 Frog     2 GRGEGREYSPAATNADNGGGKKKQKEKEMDELKKEVAMDDHKLSMEEIGRKYGTDLAKGLTNARA 66

  Fly    87 KENLERDGPNALTPPKQTPEWVKFCKNLFGGFAMLLWIGAILCFVAYSIQASTSEEPADDNLYLG 151
            .|.|.:|||||||||..||||||||:.|||||::||||||||||:||.||.:..:||.:||||||
 Frog    67 AEVLAQDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQIAMEDEPINDNLYLG 131

  Fly   152 IVLSAVVIVTGIFSYYQESKSSKIMESFKNMVPQFATVIREGEKLTLRAEDLVLGDVVEVKFGDR 216
            :||:|||||||.||||||:||||||:||||||||.|.||||||||.:.||.:|:||:||:|.|||
 Frog   132 VVLAAVVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKLQINAEMVVVGDLVEIKGGDR 196

  Fly   217 IPADIRIIEARNFKVDNSSLTGESEPQSRGAEFTHENPLETKNLAFFSTNAVEGTAKGVVISCGD 281
            :|||||||.|...||||||||||||||:|..||||||||||:|:.|||||.||||.:|:||:.||
 Frog   197 VPADIRIIIAHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNICFFSTNCVEGTGRGIVINTGD 261

  Fly   282 HTVMGRIAGLASGLDTGETPIAKEIHHFIHLITGVAVFLGVTFFVIAFILGYHWLDAVIFLIGII 346
            .|||||||.|||||:.|.||||.||.||||:||||||||||:|||::.||||.||:|||||||||
 Frog   262 RTVMGRIATLASGLEVGRTPIAMEIEHFIHIITGVAVFLGVSFFVLSLILGYSWLEAVIFLIGII 326

  Fly   347 VANVPEGLLATVTVCLTLTAKRMASKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWF 411
            ||||||||||||||||||||||||.||||||||||||||||||||||||||||||||||||||||
 Frog   327 VANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWF 391

  Fly   412 DNQIIEADTTEDQSGVQYDRTSPGFKALSRIATLCNRAEFKGGQDGVPILKKEVSGDASEAALLK 476
            ||||.||||||||||..:|:.||.:.||||||.|||||.||.||:.|.:.|::.:|||||:||||
 Frog   392 DNQIHEADTTEDQSGTTFDKRSPTWTALSRIAGLCNRAVFKVGQEKVAVSKRDTAGDASESALLK 456

  Fly   477 CMELALGDVMNIRKRNKKIAEVPFNSTNKYQVSIHETEDTNDPRYLLVMKGAPERILERCSTIFI 541
            |:||:.|.|..:|.||.|:||:|||||||:|:||||.||:.: .:||||||||||||:|||||.:
 Frog   457 CIELSCGSVRKLRDRNPKVAEIPFNSTNKFQLSIHEREDSPE-GHLLVMKGAPERILDRCSTIML 520

  Fly   542 NGKEKVLDEEMKEAFNNAYMELGGLGERVLGFCDFMLPSDKYPNGFKFNTDDINFPIDNLRFVGL 606
            :|.|:.||||||:||.|||.|||||||||||||...:|:||:..||||:||:.|||:.:|.|:||
 Frog   521 HGAEQPLDEEMKDAFQNAYFELGGLGERVLGFCHLYIPADKFQRGFKFDTDEPNFPLTDLCFIGL 585

  Fly   607 MSMIDPPRAAVPDAVAKCRSAGIKVIMVTGDHPITAKAIAKSVGIISEGNETVEDIAQRLNIPVS 671
            :||||||||||||||.|||||||||||||||||||||||||.|||||||||||||||.||||||:
 Frog   586 ISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIADRLNIPVN 650

  Fly   672 EVNPREAKAAVVHGAELRDVSSDQLDEILRYHTEIVFARTSPQQKLIIVEGCQRMGAIVAVTGDG 736
            :||||||||.||||::|:|::|:|||::|:.|||||||||||||||||||||||.||||||||||
 Frog   651 QVNPREAKACVVHGSDLKDMTSEQLDDLLKNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDG 715

  Fly   737 VNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSN 801
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
 Frog   716 VNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSN 780

  Fly   802 IPEISPFLAFILCDIPLPLGTVTILCIDLGTDMVPAISLAYEHAEADIMKRPPRDPFNDKLVNSR 866
            ||||:|||.||:.:||||||||||||||||||||||||||||.||:|||||.||:|..|||||.|
 Frog   781 IPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNPRTDKLVNER 845

  Fly   867 LISMAYGQIGMIQAAAGFFVYFVIMAENGFLPKKLFGIRKMWDSKAVNDLTDSYGQEWTYRDRKT 931
            ||||||||||||||..|||.||||:|||||||.:|.|||..||.::.||:.|||||||||..||.
 Frog   846 LISMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIRLDWDDRSNNDVEDSYGQEWTYEQRKV 910

  Fly   932 LEYTCHTAFFISIVVVQWADLIICKTRRNSIFQQGMRNWALNFGLVFETVLAAFLSYCPGMEKGL 996
            :|:|||||||.|||||||||||||||||||:|||||:|..|.|||:.||.|||||||||||:..|
 Frog   911 VEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLLEETALAAFLSYCPGMDVAL 975

  Fly   997 RMYPLKLVWWFPAIPFALAIFIYDETRRFYLRRNPGGWLEQETYY 1041
            ||||||:.|||.|.|::|.||:|||.|:..|||:||||:|:|:||
 Frog   976 RMYPLKVTWWFCAFPYSLLIFLYDEVRKLILRRDPGGWVEKESYY 1020

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atpalpha	NP_732572.1	ATPase-IIC_X-K	45..1041	CDD:273445	757/1005 (75%)
		Cation_ATPase_N	58..132	CDD:214842	45/73 (62%)
		E1-E2_ATPase	152..383	CDD:278548	182/230 (79%)
		Cation_ATPase	445..539	CDD:289987	60/93 (65%)
		COG4087	<695..770	CDD:226572	69/74 (93%)
		Cation_ATPase_C	817..1025	CDD:279079	159/207 (77%)
atp1a2	NP_001096439.1	ATPase-IIC_X-K	30..1020	CDD:273445	755/990 (76%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	460	1.000	Domainoid score	I478
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	1570	1.000	Inparanoid score	I90
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D388324at2759
OrthoFinder	1	1.000	-	-		FOG0000283
OrthoInspector	1	1.000	-	-		otm48370
Panther	1	1.100	-	-	LDO	PTHR43294
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X416
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.160