Protein Alignment NRAS and RSR1

DIOPT Version :10

• Sequence 1: NP_002515.1
• Gene: NRAS / 4893
• HGNCID: 7989
• Length: 189
• Species: Homo sapiens
• Sequence 2: NP_011668.3
• Gene: RSR1 / 853056
• SGDID: S000003384
• Length: 272
• Species: Saccharomyces cerevisiae
• Alignment Length: 181
• Identity: 86/181 - (47%)
• Similarity: 125/181 - (69%)
• Gaps: 2/181 - (1%)

Human     1 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYS 65
            |.:|||||:||||||||.||:|.:|..::|.|||||||||||.:.||.:...|:||||||..:::
Yeast     1 MRDYKLVVLGAGGVGKSCLTVQFVQGVYLDTYDPTIEDSYRKTIEIDNKVFDLEILDTAGIAQFT 65

Human    66 AMRDQYMRTGEGFLCVFAINNSKSFADINLYREQIKRVKDSDDVPMVLVGNKCDL-PTRTVDTKQ 129
            |||:.|:::|.|||.|:::.:.:|..::...|||:.|:||||.|||||:|||.|| ..|.:..::
Yeast    66 AMRELYIKSGMGFLLVYSVTDRQSLEELMELREQVLRIKDSDRVPMVLIGNKADLINERVISVEE 130

Human   130 AHELAKSYG-IPFIETSAKTRQGVEDAFYTLVREIRQYRMKKLNSSDDGTQ 179
            ..|::..:| :||.||||..|..|::.|..|||:|.:..|:.:...|...|
Yeast   131 GIEVSSKWGRVPFYETSALLRSNVDEVFVDLVRQIIRNEMESVAVKDARNQ 181

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NRAS	NP_002515.1	H_N_K_Ras_like	3..164	CDD:133338	81/162 (50%)
		Effector region	32..40		7/7 (100%)
		Hypervariable region	166..185		3/14 (21%)
RSR1	NP_011668.3	RSR1	3..166	CDD:133377	81/162 (50%)