Protein Alignment NRAS and nras

DIOPT Version :10

• Sequence 1: NP_002515.1
• Gene: NRAS / 4893
• HGNCID: 7989
• Length: 189
• Species: Homo sapiens
• Sequence 2: NP_001016763.1
• Gene: nras / 549517
• XenbaseID: XB-GENE-6085898
• Length: 189
• Species: Xenopus tropicalis
• Alignment Length: 189
• Identity: 175/189 - (92%)
• Similarity: 182/189 - (96%)
• Gaps: 0/189 - (0%)

Human     1 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYS 65
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
 Frog     1 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYS 65

Human    66 AMRDQYMRTGEGFLCVFAINNSKSFADINLYREQIKRVKDSDDVPMVLVGNKCDLPTRTVDTKQA 130
            |||||||||||||||||||||||||||||.||||||||||||||||||||||||||:||||||||
 Frog    66 AMRDQYMRTGEGFLCVFAINNSKSFADINAYREQIKRVKDSDDVPMVLVGNKCDLPSRTVDTKQA 130

Human   131 HELAKSYGIPFIETSAKTRQGVEDAFYTLVREIRQYRMKKLNSSDDGTQGCMGLPCVVM 189
            .|||:||||||||||||||||||||||||||||.|||||||:||:|..|||:.:||.:|
 Frog   131 QELARSYGIPFIETSAKTRQGVEDAFYTLVREIHQYRMKKLDSSEDNNQGCIRIPCKLM 189

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NRAS	NP_002515.1	H_N_K_Ras_like	3..164	CDD:133338	156/160 (98%)
		Effector region	32..40		7/7 (100%)
		Hypervariable region	166..185		12/18 (67%)
nras	NP_001016763.1	H_N_K_Ras_like	3..163	CDD:133338	155/159 (97%)