DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment l(3)73Ah and Pcgf3

DIOPT Version :9

Sequence 1:	NP_001246797.1	Gene:	l(3)73Ah / 48903	FlyBaseID:	FBgn0002283	Length:	222	Species:	Drosophila melanogaster
Sequence 2:	NP_001363929.1	Gene:	Pcgf3 / 69587	MGIID:	1916837	Length:	259	Species:	Mus musculus

Alignment Length:	227	Identity:	132/227 - (58%)
Similarity:	163/227 - (71%)	Gaps:	21/227 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MERRVKLKTINPHITCKICGGYFIDATTVTECLHTFCKSCLVKHLEEKKTCPTCDNIIHQSHPLQ 65
            :.|::||..||.||||::|.||.||||||||||||||:|||||:|||..|||||..:||||||||
Mouse     2 LTRKIKLWDINAHITCRLCSGYLIDATTVTECLHTFCRSCLVKYLEENNTCPTCRIVIHQSHPLQ 66

  Fly    66 YISFDRTMQDIVYKLVPKLQEDESRRERDFYKSRNMPCPKDI------------TQNHE---DDN 115
            ||..|||||||||||||.|||.|.|::|:||....|..|.||            .:|.|   |||
Mouse    67 YIGHDRTMQDIVYKLVPGLQEAEMRKQREFYHKLGMEVPGDIKGEACSAKQHLDPRNGETKADDN 131

  Fly   116 EKVMDA----HAESDFHRLDEQVNVCLECISNNFKNLQRRFIRCSSQATITHLKKLVAKKILNGI 176
            .....|    ..::|:||.||||::||||.|:..:.|:|::||||:|||:.||||.:|||:  .:
Mouse   132 SNKETAEEKQEEDNDYHRSDEQVSICLECNSSKLRGLKRKWIRCSAQATVLHLKKFIAKKL--NL 194

  Fly   177 EKYREIDILCNEELLGKDHTLKFVYVTRWRFR 208
            ..:.|:|||||||:||||||||||.||||||:
Mouse   195 SSFNELDILCNEEILGKDHTLKFVVVTRWRFK 226

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(3)73Ah	NP_001246797.1	RING-HC_PCGF3	13..59	CDD:319649	34/45 (76%)
l(3)73Ah	NP_001246797.1	RAWUL_PCGF3	133..217	CDD:340603	47/76 (62%)
Pcgf3	NP_001363929.1	RING-HC_PCGF3	14..60	CDD:319649	34/45 (76%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	115..148		7/32 (22%)
		RAWUL_PCGF3	153..226	CDD:340603	46/74 (62%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167850175
Domainoid	1	1.000	99	1.000	Domainoid score	I7125
eggNOG	1	0.900	-	-		E1_KOG2660
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4605
Inparanoid	1	1.050	283	1.000	Inparanoid score	I2859
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48635
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000290
OrthoInspector	1	1.000	-	-		oto94057
orthoMCL	1	0.900	-	-		OOG6_107223
Panther	1	1.100	-	-	LDO	PTHR45893
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3764
SonicParanoid	1	1.000	-	-		X607
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.790