DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment l(3)73Ah and pcgf5b

DIOPT Version :9

Sequence 1:	NP_001246797.1	Gene:	l(3)73Ah / 48903	FlyBaseID:	FBgn0002283	Length:	222	Species:	Drosophila melanogaster
Sequence 2:	NP_001038700.1	Gene:	pcgf5b / 692252	ZFINID:	ZDB-GENE-060512-34	Length:	232	Species:	Danio rerio

Alignment Length:	234	Identity:	92/234 - (39%)
Similarity:	150/234 - (64%)	Gaps:	23/234 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 RRVKLKTINPHITCKICGGYFIDATTVTECLHTFCKSCLVKHLEEKKTCPTCDNIIHQSHPLQYI 67
            |:..::..|..|||.:|.||.|..||||||||||||||:|:|.|:...||.|...:|:::||:.:
Zfish     5 RKHLVRDFNHFITCFVCKGYLIKPTTVTECLHTFCKSCIVQHFEDSNDCPKCGIQVHETNPLEML 69

  Fly    68 SFDRTMQDIVYKLVPKLQEDESRRERDFYKSR-----NMPCPKDITQNHEDDNEKVMDAHAESDF 127
            ..|.|::::::||||.|:|.|.::|.:|::.:     |.|..|....:.|||::      .:.|:
Zfish    70 RLDNTLEEVIFKLVPGLREKEQQQEDEFWRRKESNDENGPMCKKRRVDEEDDDK------GDGDY 128

  Fly   128 HRLDEQVNVCLECI-------SNNFKNLQRRFIRCSSQATITHLKKLVAKKILNGIEKYREIDIL 185
            ||.|.|:.:||:|:       .|..|.|.::|||||::.|:..:||.::.|:  .:....|:|:|
Zfish   129 HRSDPQIAICLDCLRINGQMGENIVKGLMKKFIRCSTRVTVGTIKKFLSLKL--KLPSSYELDVL 191

  Fly   186 CNEELLGKDHTLKFVYVTRWRFRDP---PLRLQFRPRVE 221
            ||.|::|||||::|:|:||||.|..   |:.|::|||::
Zfish   192 CNGEIMGKDHTMEFIYMTRWRLRGENVYPMVLEYRPRID 230

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(3)73Ah	NP_001246797.1	RING-HC_PCGF3	13..59	CDD:319649	27/45 (60%)
l(3)73Ah	NP_001246797.1	RAWUL_PCGF3	133..217	CDD:340603	36/93 (39%)
pcgf5b	NP_001038700.1	zf-C3HC4	18..56	CDD:278524	24/37 (65%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	93..128		8/40 (20%)
		RAWUL	150..226	CDD:292824	32/77 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	68	1.000	Domainoid score	I9708
eggNOG	1	0.900	-	-		E1_KOG2660
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	198	1.000	Inparanoid score	I3772
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1203951at2759
OrthoFinder	1	1.000	-	-		FOG0000290
OrthoInspector	1	1.000	-	-		otm26311
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X607
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.870