DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment l(3)73Ah and Pcgf5

DIOPT Version :9

Sequence 1:	NP_001246797.1	Gene:	l(3)73Ah / 48903	FlyBaseID:	FBgn0002283	Length:	222	Species:	Drosophila melanogaster
Sequence 2:	XP_017445196.1	Gene:	Pcgf5 / 681178	RGDID:	1583513	Length:	253	Species:	Rattus norvegicus

Alignment Length:	223	Identity:	94/223 - (42%)
Similarity:	147/223 - (65%)	Gaps:	24/223 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 ERRVKLKTINPHITCKICGGYFIDATTVTECLHTFCKSCLVKHLEEKKTCPTCDNIIHQSHPLQY 66
            :|:..:|..||:|||.||.||.|..||||||||||||:|:|:|.|:...||.|.|.:|:::||:.
  Rat     4 QRKHLVKDFNPYITCYICKGYLIKPTTVTECLHTFCKTCIVQHFEDSNDCPRCGNQVHETNPLEM 68

  Fly    67 ISFDRTMQDIVYKLVPKLQEDESRRERDFYKSRNMPCPKDITQNHEDDNEKVMDAHA-------- 123
            :..|.|:::|::||||.|:|.|.:||.:|:| :|.|     .:|.:|:..||..:.|
  Rat    69 LRLDNTLEEIIFKLVPGLREQELQRELEFWK-KNKP-----QENGQDEVSKVDKSKADEEGDENQ 127

  Fly   124 -ESDFHRLDEQVNVCLECISNN-------FKNLQRRFIRCSSQATITHLKKLVAKKILNGIEKYR 180
             :.|:||.|.|:.:||:|:.|:       .|.|.::|||||::.|:..:||.::.|:  .:....
  Rat   128 DDKDYHRSDPQIAICLDCLRNHGQSGDNVVKGLMKKFIRCSTRVTVGTIKKFLSLKL--KLPSSY 190

  Fly   181 EIDILCNEELLGKDHTLKFVYVTRWRFR 208
            |:|:|||.|::|||||::|:|:||||.|
  Rat   191 ELDVLCNGEIMGKDHTMEFIYMTRWRLR 218

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(3)73Ah	NP_001246797.1	RING-HC_PCGF3	13..59	CDD:319649	28/45 (62%)
l(3)73Ah	NP_001246797.1	RAWUL_PCGF3	133..217	CDD:340603	34/83 (41%)
Pcgf5	XP_017445196.1	zf-C3HC4	18..56	CDD:278524	24/37 (65%)
Pcgf5	XP_017445196.1	RAWUL	154..216	CDD:292824	26/63 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2660
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1203951at2759
OrthoFinder	1	1.000	-	-		FOG0000290
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X607
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.820