Protein Alignment NPY5R and npy5r

DIOPT Version :10

• Sequence 1: XP_011530317.1
• Gene: NPY5R / 4889
• HGNCID: 7958
• Length: 452
• Species: Homo sapiens
• Sequence 2: NP_001072244.1
• Gene: npy5r / 779693
• XenbaseID: XB-GENE-960863
• Length: 448
• Species: Xenopus tropicalis
• Alignment Length: 447
• Identity: 315/447 - (70%)
• Similarity: 380/447 - (85%)
• Gaps: 2/447 - (0%)

Human     8 MDLELDEYYNKTLA-TENNTAATRNSDFPVWDDYKSSVDDLQYFLIGLYTFVSLLGFMGNLLILM 71
            ||||:::..|:|:. .||:|:.||:|.||.|:||.|||||::||||||||||||||||||||||:
 Frog     1 MDLEIEDVNNRTVTKDENSTSETRDSSFPEWEDYNSSVDDIRYFLIGLYTFVSLLGFMGNLLILL 65

Human    72 ALMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQWMFGKVMCHIMPFLQCVSVLVST 136
            |:.|||.|||.:|:||||||||||||||||||||||.||||||:||:||||::|||||||||:||
 Frog    66 AIFKKRKQKTIINYLIGNLAFSDILVVLFCSPFTLTCVLLDQWIFGEVMCHVVPFLQCVSVLIST 130

Human   137 LILISIAIVRYHMIKHPISNNLTANHGYFLIATVWTLGFAICSPLPVFHSLVELQETFGSALLSS 201
            |:|:|||:|||||||||:|.|||||||||||||||||||.|||||||||.::.|:|.|....|.:
 Frog   131 LMLMSIALVRYHMIKHPLSTNLTANHGYFLIATVWTLGFTICSPLPVFHKIINLREAFNLDSLIN 195

Human   202 RYLCVESWPSDSYRIAFTISLLLVQYILPLVCLTVSHTSVCRSISCGLSNKENRLEENEMINLTL 266
            .|||:|||||||||||||||||||||||||.|||:|||||||||...|.:::.::||||||||||
 Frog   196 SYLCIESWPSDSYRIAFTISLLLVQYILPLSCLTISHTSVCRSIGSRLPSRDTKVEENEMINLTL 260

Human   267 HPSKKSGPQVKLSGSHKWSYSFIKKHRRRYSKKTACVLPAPERPSQENHSRILPENFGSVRSQLS 331
            ...|....::::|.|.:||||.::|||||||||:|.|:||..|.:||:::..:||...:.||...
 Frog   261 QQPKNHRSELEISSSRRWSYSCVRKHRRRYSKKSASVVPAILRRNQESNTGDIPETSMTERSHTL 325

Human   332 SSSKFIPGVPTCFEIKPEENSDVHE-LRVKRSVTRIKKRSRSVFYRLTILILVFAVSWMPLHLFH 395
            .||.::||||.|||:||||||::|. :.|.:|:|||:||||.||.||||||:.||||||||||||
 Frog   326 PSSVYLPGVPICFEMKPEENSEMHNMISVSKSITRIRKRSRRVFCRLTILIIAFAVSWMPLHLFH 390

Human   396 VVTDFNDNLISNRHFKLVYCICHLLGMMSCCLNPILYGFLNNGIKADLVSLIHCLHM 452
            :|||||.||||||||||||||||||||:|||||||||||||:||||||:|||.|..:
 Frog   391 LVTDFNANLISNRHFKLVYCICHLLGMVSCCLNPILYGFLNDGIKADLMSLIKCFQI 447

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NPY5R	XP_011530317.1	7tmA_NPY5R	49..443	CDD:320520	287/394 (73%)
		TM helix 1	50..76	CDD:320520	22/25 (88%)
		TM helix 2	83..108	CDD:320520	22/24 (92%)
		TM helix 3	121..151	CDD:320520	23/29 (79%)
		TM helix 4	162..183	CDD:320520	19/20 (95%)
		TM helix 5	215..244	CDD:320520	26/28 (93%)
		TM helix 6	368..398	CDD:320520	24/29 (83%)
		TM helix 7	411..436	CDD:320520	23/24 (96%)
npy5r	NP_001072244.1	7tmA_NPY5R	43..438	CDD:320520	287/394 (73%)
		TM helix 1	44..70	CDD:320520	22/25 (88%)
		TM helix 2	77..102	CDD:320520	22/24 (92%)
		TM helix 3	115..145	CDD:320520	23/29 (79%)
		TM helix 4	156..177	CDD:320520	19/20 (95%)
		TM helix 5	209..238	CDD:320520	26/28 (93%)
		TM helix 6	363..393	CDD:320520	24/29 (83%)
		TM helix 7	406..431	CDD:320520	23/24 (96%)