Protein Alignment NPY5R and map3

DIOPT Version :10

• Sequence 1: XP_011530317.1
• Gene: NPY5R / 4889
• HGNCID: 7958
• Length: 452
• Species: Homo sapiens
• Sequence 2: NP_001342813.1
• Gene: map3 / 2542271
• PomBaseID: SPAC3F10.10C
• Length: 365
• Species: Schizosaccharomyces pombe
• Alignment Length: 427
• Identity: 83/427 - (19%)
• Similarity: 139/427 - (32%)
• Gaps: 171/427 - (40%)

Human    52 IGL-YTFVSLLGFMGNLLILMALMKKRN----------QKTTVNFLIGNLAFSDILVVLFCSPFT 105
            ||: |.|.:....:.::.||...::.||          ..||:.:::.:..:|        :|:.
pombe     4 IGIFYQFYAYFALVLSIPILYMQLRARNIPCLLLLFWLTLTTLIYVVESAIWS--------NPYA 60

Human   106 LTSVLLDQWMFGKVMCHIMP-FLQCVSVLVS----TLILISIAIVRYHMIKHPISNNLTANHGYF 165
            .|.    :|| |..:|.|.. .:.|.|:.:.    ||:|....::|.   .||:.....
pombe    61 ETI----RWM-GYGLCDITSRIVTCSSIGIPASAFTLVLYLDTVIRR---DHPLKRYEN------ 111

Human   166 LIATVWTLGFAICSPLPVFHSLVELQETFGSALLSSRY--LCVESWPSDSYRIAFTISLLLVQYI 228
               .:|.:..:|..||.:...:|.|:        |:||  :|:....|..|:..:|   ||..||
pombe   112 ---WIWHVCLSILLPLIIMAMMVPLE--------SNRYVVICMNGCYSSFYQTWYT---LLFFYI 162

Human   229 LPLVCLTVSHTSVCRSISCGLSNKENRLEENEMINLTLHPSKKSGPQVKLSGSHKWSYSFIKKHR 293
            .|  ||          :|.|                                    ...|:.:..
pombe   163 PP--CL----------LSFG------------------------------------GLFFVSRIV 179

Human   294 RRYSKKTACVLPAPERPSQENHSRILPENFGSVRSQLSSSSKFIPGVPTCFEIKPEENSDVHELR 358
            ..|.::        :|..|:...|         .|||:|
pombe   180 VLYWRR--------QRELQQFFQR---------DSQLTS-------------------------- 201

Human   359 VKRSVTRIKKRSRSVFYRLTILILVFAVSWMPLHLFHVVTD--------FNDNLISNRHFK-LVY 414
                     ||    |.||..|..||.:.:.||.:|.||.:        ||..|:...|.: :.|
pombe   202 ---------KR----FLRLLCLAAVFFLGYFPLTIFMVVANGKLQQFLPFNHELVEAWHQESITY 253

Human   415 CICHLLGMMSCCLNPILY----GFLNNGIKADLVSLI 447
            .....:|:.......:||    .|..:|...:.|:||
pombe   254 YPTTKVGLNDWVPPTVLYLMSLFFSTSGGWTEKVALI 290

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NPY5R	XP_011530317.1	7tmA_NPY5R	49..443	CDD:320520	80/421 (19%)
		TM helix 1	50..76	CDD:320520	6/24 (25%)
		TM helix 2	83..108	CDD:320520	2/24 (8%)
		TM helix 3	121..151	CDD:320520	8/34 (24%)
		TM helix 4	162..183	CDD:320520	4/20 (20%)
		TM helix 5	215..244	CDD:320520	8/28 (29%)
		TM helix 6	368..398	CDD:320520	12/29 (41%)
		TM helix 7	411..436	CDD:320520	5/29 (17%)
map3	NP_001342813.1	STE3	10..280	CDD:460437	76/409 (19%)