Protein Alignment NPY5R and Npy5r

DIOPT Version :10

• Sequence 1: XP_011530317.1
• Gene: NPY5R / 4889
• HGNCID: 7958
• Length: 452
• Species: Homo sapiens
• Sequence 2: NP_037001.1
• Gene: Npy5r / 25340
• RGDID: 3199
• Length: 445
• Species: Rattus norvegicus
• Alignment Length: 445
• Identity: 394/445 - (88%)
• Similarity: 415/445 - (93%)
• Gaps: 1/445 - (0%)

Human     8 MDLELDEYYNKTLATENNTAATRNSDFPVWDDYKSSVDDLQYFLIGLYTFVSLLGFMGNLLILMA 72
            |:.:|:|::|||..|||||||.||:.||.|:||:.||||||||||||||||||||||||||||||
  Rat     1 MEFKLEEHFNKTFVTENNTAAARNAAFPAWEDYRGSVDDLQYFLIGLYTFVSLLGFMGNLLILMA 65

Human    73 LMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQWMFGKVMCHIMPFLQCVSVLVSTL 137
            :|||||||||||||||||||||||||||||||||||||||||||||.||||||||||||||||||
  Rat    66 VMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQWMFGKAMCHIMPFLQCVSVLVSTL 130

Human   138 ILISIAIVRYHMIKHPISNNLTANHGYFLIATVWTLGFAICSPLPVFHSLVELQETFGSALLSSR 202
            |||||||||||||||||||||||||||||||||||||||||||||||||||||:||||||||||:
  Rat   131 ILISIAIVRYHMIKHPISNNLTANHGYFLIATVWTLGFAICSPLPVFHSLVELKETFGSALLSSK 195

Human   203 YLCVESWPSDSYRIAFTISLLLVQYILPLVCLTVSHTSVCRSISCGLSNKENRLEENEMINLTLH 267
            ||||||||||||||||||||||||||||||||||||||||||||||||:|||||||||||||||.
  Rat   196 YLCVESWPSDSYRIAFTISLLLVQYILPLVCLTVSHTSVCRSISCGLSHKENRLEENEMINLTLQ 260

Human   268 PSKKSGPQVKLSGSHKWSYSFIKKHRRRYSKKTACVLPAPERPSQENHSRILPENFGSVRSQLSS 332
            |||||..|.|...:.|||||||:|||||||||||||||||..|||..|..: |||..|||||||.
  Rat   261 PSKKSRNQAKTPSTQKWSYSFIRKHRRRYSKKTACVLPAPAGPSQGKHLAV-PENPASVRSQLSP 324

Human   333 SSKFIPGVPTCFEIKPEENSDVHELRVKRSVTRIKKRSRSVFYRLTILILVFAVSWMPLHLFHVV 397
            |||.|||||.|||:||||:||.||:|||||:|||||||||||||||||||||||||||||:||||
  Rat   325 SSKVIPGVPICFEVKPEESSDAHEMRVKRSITRIKKRSRSVFYRLTILILVFAVSWMPLHVFHVV 389

Human   398 TDFNDNLISNRHFKLVYCICHLLGMMSCCLNPILYGFLNNGIKADLVSLIHCLHM 452
            ||||||||||||||||||||||||||||||||||||||||||||||.:|||||||
  Rat   390 TDFNDNLISNRHFKLVYCICHLLGMMSCCLNPILYGFLNNGIKADLRALIHCLHM 444

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NPY5R	XP_011530317.1	7tmA_NPY5R	49..443	CDD:320520	359/393 (91%)
		TM helix 1	50..76	CDD:320520	24/25 (96%)
		TM helix 2	83..108	CDD:320520	24/24 (100%)
		TM helix 3	121..151	CDD:320520	29/29 (100%)
		TM helix 4	162..183	CDD:320520	20/20 (100%)
		TM helix 5	215..244	CDD:320520	28/28 (100%)
		TM helix 6	368..398	CDD:320520	28/29 (97%)
		TM helix 7	411..436	CDD:320520	24/24 (100%)
Npy5r	NP_037001.1	7tmA_NPY5R	42..435	CDD:320520	359/393 (91%)
		TM helix 1	43..69	CDD:320520	24/25 (96%)
		TM helix 2	76..101	CDD:320520	24/24 (100%)
		TM helix 3	114..144	CDD:320520	29/29 (100%)
		TM helix 4	155..176	CDD:320520	20/20 (100%)
		TM helix 5	208..237	CDD:320520	28/28 (100%)
		TM helix 6	360..390	CDD:320520	28/29 (97%)
		TM helix 7	403..428	CDD:320520	24/24 (100%)