Protein Alignment NPY5R and Npy5r

DIOPT Version :10

• Sequence 1: XP_011530317.1
• Gene: NPY5R / 4889
• HGNCID: 7958
• Length: 452
• Species: Homo sapiens
• Sequence 2: NP_057917.2
• Gene: Npy5r / 18168
• MGIID: 108082
• Length: 466
• Species: Mus musculus
• Alignment Length: 466
• Identity: 397/466 - (85%)
• Similarity: 420/466 - (90%)
• Gaps: 22/466 - (4%)

Human     8 MDLELDEYYNKTLATENNTAAT---------------------RNSDFPVWDDYKSSVDDLQYFL 51
            |:::|:|::|||..|||||||:                     ||:.||||:||:.|||||||||
Mouse     1 MEVKLEEHFNKTFVTENNTAASQNTASPAWEDYRGTENNTSAARNTAFPVWEDYRGSVDDLQYFL 65

Human    52 IGLYTFVSLLGFMGNLLILMALMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQWMF 116
            |||||||||||||||||||||:|||||||||||||||||||||||||||||||||||||||||||
Mouse    66 IGLYTFVSLLGFMGNLLILMAVMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQWMF 130

Human   117 GKVMCHIMPFLQCVSVLVSTLILISIAIVRYHMIKHPISNNLTANHGYFLIATVWTLGFAICSPL 181
            ||.||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   131 GKAMCHIMPFLQCVSVLVSTLILISIAIVRYHMIKHPISNNLTANHGYFLIATVWTLGFAICSPL 195

Human   182 PVFHSLVELQETFGSALLSSRYLCVESWPSDSYRIAFTISLLLVQYILPLVCLTVSHTSVCRSIS 246
            |||||||||:||||||||||:||||||||||||||||||||||||||||||||||||||||||||
Mouse   196 PVFHSLVELKETFGSALLSSKYLCVESWPSDSYRIAFTISLLLVQYILPLVCLTVSHTSVCRSIS 260

Human   247 CGLSNKENRLEENEMINLTLHPSKKSGPQVKLSGSHKWSYSFIKKHRRRYSKKTACVLPAPERPS 311
            ||||:|||||||||||||||||||||..|.|...:.|||||||:|||||||||||||||||..||
Mouse   261 CGLSHKENRLEENEMINLTLHPSKKSRDQAKPPSTQKWSYSFIRKHRRRYSKKTACVLPAPAGPS 325

Human   312 QENHSRILPENFGSVRSQLSSSSKFIPGVPTCFEIKPEENSDVHELRVKRSVTRIKKRSRSVFYR 376
            ||.|..: |||.||||||||.|||.|||||.|||:||||:||..|:|||||:|||||||||||||
Mouse   326 QEKHLTV-PENPGSVRSQLSPSSKVIPGVPICFEVKPEESSDAQEMRVKRSLTRIKKRSRSVFYR 389

Human   377 LTILILVFAVSWMPLHLFHVVTDFNDNLISNRHFKLVYCICHLLGMMSCCLNPILYGFLNNGIKA 441
            ||||||||||||||||:||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   390 LTILILVFAVSWMPLHVFHVVTDFNDNLISNRHFKLVYCICHLLGMMSCCLNPILYGFLNNGIKA 454

Human   442 DLVSLIHCLHM 452
            ||.:|||||||
Mouse   455 DLRALIHCLHM 465

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NPY5R	XP_011530317.1	7tmA_NPY5R	49..443	CDD:320520	361/393 (92%)
		TM helix 1	50..76	CDD:320520	24/25 (96%)
		TM helix 2	83..108	CDD:320520	24/24 (100%)
		TM helix 3	121..151	CDD:320520	29/29 (100%)
		TM helix 4	162..183	CDD:320520	20/20 (100%)
		TM helix 5	215..244	CDD:320520	28/28 (100%)
		TM helix 6	368..398	CDD:320520	28/29 (97%)
		TM helix 7	411..436	CDD:320520	24/24 (100%)
Npy5r	NP_057917.2	7tmA_NPY5R	63..456	CDD:320520	361/393 (92%)
		TM helix 1	64..90	CDD:320520	24/25 (96%)
		TM helix 2	97..122	CDD:320520	24/24 (100%)
		TM helix 3	135..165	CDD:320520	29/29 (100%)
		TM helix 4	176..197	CDD:320520	20/20 (100%)
		TM helix 5	229..258	CDD:320520	28/28 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	323..346		16/23 (70%)
		TM helix 6	381..411	CDD:320520	28/29 (97%)
		TM helix 7	424..449	CDD:320520	24/24 (100%)