DRSC/TRiP Functional Genomics Resources

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Protein Alignment NPY2R and sNPF-R

DIOPT Version :10

Sequence 1:NP_000901.1 Gene:NPY2R / 4887 HGNCID:7957 Length:381 Species:Homo sapiens
Sequence 2:NP_524176.1 Gene:sNPF-R / 40195 FlyBaseID:FBgn0036934 Length:600 Species:Drosophila melanogaster


Alignment Length:354 Identity:121/354 - (34%)
Similarity:177/354 - (50%) Gaps:65/354 - (18%)


- Green bases have known domain annotations that are detailed below.


Human    49 VQVVLILAYCSIILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLM 113
            ||:...:.|.::.:|||.||.||.:||::.::|:||||.||.|||::|:|:..|.:|||..||.|
  Fly    62 VQIFFYVLYATVFVLGVFGNVLVCYVVLRNRAMQTVTNIFITNLALSDILLCVLAVPFTPLYTFM 126

Human   114 GEWKMGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVY--HLESKISKRISFLIIGLAWGIS 176
            |.|..|..|||||.:|||.::.:||:|||.||:||:..|:|  |...|:|..|.  ||...|.|:
  Fly   127 GRWAFGRSLCHLVSFAQGCSIYISTLTLTSIAIDRYFVIIYPFHPRMKLSTCIG--IIVSIWVIA 189

Human   177 ALLASPLAIFREY-------------SLIEI-----------------IPD-------------- 197
            .|...|..::.:.             :|:|.                 .||              
  Fly   190 LLATVPYGMYMKMTNELVNGTQTGNETLVEATLMLNGSFVAQGSGFIEAPDSTSATQAYMQVMTA 254

Human   198 --------FEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYTRIWSKL--KNHVSP 252
                    :..|.|.|.||.|:   |..|:...:..:.:|||..|||..|..|..||  :....|
  Fly   255 GSTGPEMPYVRVYCEENWPSEQ---YRKVFGAITTTLQFVLPFFIISICYVWISVKLNQRARAKP 316

Human   253 GAANDHYHQ----RRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDLKEYKLIFTVFHII 313
            |:.:....:    |:::|.:||:.:|.||.:||||::...:..|.|.:..:.:.|.|.|.|.|.|
  Fly   317 GSKSSRREEADRDRKKRTNRMLIAMVAVFGLSWLPINVVNIFDDFDDKSNEWRFYILFFFVAHSI 381

Human   314 AMCSTFANPLLYGWMNSNYRKAFLSAFRC 342
            ||.||..||.||.|:|.|:||.|.....|
  Fly   382 AMSSTCYNPFLYAWLNENFRKEFKHVLPC 410

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
NPY2RNP_000901.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..35
7tmA_NPY2R 51..336 CDD:320521 117/344 (34%)
TM helix 1 52..78 CDD:320521 10/25 (40%)
TM helix 2 85..110 CDD:320521 13/24 (54%)
TM helix 3 123..153 CDD:320521 16/29 (55%)
TM helix 4 164..185 CDD:320521 7/20 (35%)
TM helix 5 216..245 CDD:320521 9/28 (32%)
TM helix 6 261..291 CDD:320521 11/33 (33%)
TM helix 7 304..329 CDD:320521 14/24 (58%)
sNPF-RNP_524176.1 7tmA_NPYR-like 64..404 CDD:320331 117/344 (34%)
TM helix 1 65..91 CDD:320331 10/25 (40%)
TM helix 2 98..123 CDD:320331 13/24 (54%)
TM helix 3 136..166 CDD:320331 16/29 (55%)
TM helix 4 177..198 CDD:320331 7/22 (32%)
TM helix 5 278..307 CDD:320331 9/28 (32%)
TM helix 6 329..359 CDD:320331 11/29 (38%)
TM helix 7 372..397 CDD:320331 14/24 (58%)
Blue background indicates that the domain is not in the aligned region.

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