DRSC/TRiP Functional Genomics Resources

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Protein Alignment NPY2R and map3

DIOPT Version :10

Sequence 1:NP_000901.1 Gene:NPY2R / 4887 HGNCID:7957 Length:381 Species:Homo sapiens
Sequence 2:NP_001342813.1 Gene:map3 / 2542271 PomBaseID:SPAC3F10.10C Length:365 Species:Schizosaccharomyces pombe


Alignment Length:318 Identity:62/318 - (19%)
Similarity:112/318 - (35%) Gaps:108/318 - (33%)


- Green bases have known domain annotations that are detailed below.


Human    69 SLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLM------GEWK---------M 118
            :||:.:.|.:..:|...             :..|.|.|.||.|.:      ..|.         |
pombe    15 ALVLSIPILYMQLRARN-------------IPCLLLLFWLTLTTLIYVVESAIWSNPYAETIRWM 66

Human   119 GPVLCHL---VPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLA 180
            |..||.:   :.....:.:..|..|| |:.||    .|...:..:.:..:::     |.:...:.
pombe    67 GYGLCDITSRIVTCSSIGIPASAFTL-VLYLD----TVIRRDHPLKRYENWI-----WHVCLSIL 121

Human   181 SPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFS----YTR 241
            .||.|..  .::.:..:..:|.|..   |...|.|.|.|   :||..|:.|. ::||.    .:|
pombe   122 LPLIIMA--MMVPLESNRYVVICMN---GCYSSFYQTWY---TLLFFYIPPC-LLSFGGLFFVSR 177

Human   242 I----WSKLKNHVSPGAANDHYHQRRQKTTK---MLVCVVVVFAVSWLPLHAFQLAVDIDSQVLD 299
            |    |.:.:.      ....:.:..|.|:|   .|:|:..||.:.:.||               
pombe   178 IVVLYWRRQRE------LQQFFQRDSQLTSKRFLRLLCLAAVFFLGYFPL--------------- 221

Human   300 LKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVSVTF 357
                    |:|.::      ||..|..::..|:           :.::|.|.| |:|:
pombe   222 --------TIFMVV------ANGKLQQFLPFNH-----------ELVEAWHQE-SITY 253

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
NPY2RNP_000901.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..35
7tmA_NPY2R 51..336 CDD:320521 57/295 (19%)
TM helix 1 52..78 CDD:320521 3/8 (38%)
TM helix 2 85..110 CDD:320521 4/24 (17%)
TM helix 3 123..153 CDD:320521 7/32 (22%)
TM helix 4 164..185 CDD:320521 3/20 (15%)
TM helix 5 216..245 CDD:320521 11/36 (31%)
TM helix 6 261..291 CDD:320521 9/32 (28%)
TM helix 7 304..329 CDD:320521 5/24 (21%)
map3NP_001342813.1 STE3 10..280 CDD:460437 62/318 (19%)
Blue background indicates that the domain is not in the aligned region.

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