Protein Alignment NPY2R and npy2r

DIOPT Version :10

• Sequence 1: NP_000901.1
• Gene: NPY2R / 4887
• HGNCID: 7957
• Length: 381
• Species: Homo sapiens
• Sequence 2: XP_004911210.1
• Gene: npy2r / 100498351
• XenbaseID: XB-GENE-983413
• Length: 408
• Species: Xenopus tropicalis
• Alignment Length: 380
• Identity: 266/380 - (70%)
• Similarity: 316/380 - (83%)
• Gaps: 11/380 - (2%)

Human     1 MGPIGAEADENQTVEEMKVEQ----YGP-QTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSI 60
            ||.|.:|.:||:| |::|.|.    |.. .|||..:|.   :|||||.|||:.|||||||||.||
 Frog    23 MGRIASEKNENRT-EDIKTEMNTWFYAAGLTTPYNDLT---KPELIDITKLLSVQVVLILAYSSI 83

Human    61 ILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGPVLCHL 125
            |||||:||||||:||||||:|||||||||.||||:||:||||||||||.|||:.:||.|.|||||
 Frog    84 ILLGVLGNSLVIYVVIKFKTMRTVTNFFIVNLAVSDLMVNTLCLPFTLVYTLLDDWKFGTVLCHL 148

Human   126 VPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLASPLAIFREYS 190
            |.|:|||||||||:||.|||||||||||||||||||.:|.|:|||:.|..|||||||||||:|||
 Frog   149 VTYSQGLAVQVSTVTLMVIALDRHRCIVYHLESKISTKICFMIIGITWVCSALLASPLAIFKEYS 213

Human   191 LIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYTRIWSKLKNHVSPGAA 255
            :|.|..||:|.||:|:||..:.: |||:||:|.|||.|::||.|||::|.|||:|||||||||..
 Frog   214 VIVISSDFQIQACSERWPVGDLN-YGTIYSISMLLIQYIVPLAIISYAYIRIWTKLKNHVSPGGG 277

Human   256 NDHYHQRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDLKEYKLIFTVFHIIAMCSTFA 320
            ||||||||:|||||||.|||||||.|||.||||||.|||.:||||.|||||:|:||:||||||||
 Frog   278 NDHYHQRRRKTTKMLVAVVVVFAVCWLPFHAFQLASDIDGKVLDLNEYKLIYTIFHVIAMCSTFA 342

Human   321 NPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVSVTFK-AKKNLEVRKNSGPNDS 374
            |||||||||:|||.|||:||:||||:|:||.||||..: .||.|||::.:|.:|:
 Frog   343 NPLLYGWMNNNYRTAFLTAFKCEQRMDSIHPEVSVAIQLKKKQLEVKEINGTSDN 397

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NPY2R	NP_000901.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..35		15/38 (39%)
		7tmA_NPY2R	51..336	CDD:320521	218/284 (77%)
		TM helix 1	52..78	CDD:320521	22/25 (88%)
		TM helix 2	85..110	CDD:320521	21/24 (88%)
		TM helix 3	123..153	CDD:320521	25/29 (86%)
		TM helix 4	164..185	CDD:320521	14/20 (70%)
		TM helix 5	216..245	CDD:320521	18/28 (64%)
		TM helix 6	261..291	CDD:320521	25/29 (86%)
		TM helix 7	304..329	CDD:320521	21/24 (88%)
npy2r	XP_004911210.1	7tmA_NPY2R	74..358	CDD:320521	218/284 (77%)
		TM helix 1	75..101	CDD:320521	22/25 (88%)
		TM helix 2	108..133	CDD:320521	21/24 (88%)
		TM helix 3	146..176	CDD:320521	25/29 (86%)
		TM helix 4	187..208	CDD:320521	14/20 (70%)
		TM helix 5	238..267	CDD:320521	18/28 (64%)
		TM helix 6	283..313	CDD:320521	25/29 (86%)
		TM helix 7	326..351	CDD:320521	21/24 (88%)