DRSC/TRiP Functional Genomics Resources

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Protein Alignment NPY2R and npy2r

DIOPT Version :10

Sequence 1:NP_000901.1 Gene:NPY2R / 4887 HGNCID:7957 Length:381 Species:Homo sapiens
Sequence 2:XP_021331562.2 Gene:npy2r / 100003852 ZFINID:ZDB-GENE-040924-8 Length:379 Species:Danio rerio


Alignment Length:328 Identity:209/328 - (63%)
Similarity:256/328 - (78%) Gaps:5/328 - (1%)


- Green bases have known domain annotations that are detailed below.


Human    40 LIDSTKLIEVQVVLILAYCSIILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCL 104
            |.|||||:.|||:|||||.:||..|:.||||||:||.||:::.||||:||.||||||||||||||
Zfish    40 LEDSTKLVGVQVILILAYSTIIFFGMTGNSLVIYVVYKFRNLHTVTNYFIVNLAVADLLVNTLCL 104

Human   105 PFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLII 169
            ||||.|||.||||.|.|:|:|:||||||||.||||||.||||||:|.||||:|:|:||.:..::|
Zfish   105 PFTLMYTLYGEWKFGQVMCYLLPYAQGLAVHVSTITLNVIALDRYRSIVYHMETKMSKDMCVVVI 169

Human   170 GLAWGISALLASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGI 234
            .:.|..||:|||||||||||...::.|:..|..|.|||||  .|..||:||::...:.|.|||.|
Zfish   170 AITWVASAILASPLAIFREYVTFDLSPEQTIQGCAEKWPG--SSTDGTIYSIAMFFLQYGLPLSI 232

Human   235 ISFSYTRIWSKLKNHVSPGAANDHYHQRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLD 299
            |||:|||||:||:||||||......||||||||||||.|||||.|||||.|||||||||||.||:
Zfish   233 ISFAYTRIWNKLRNHVSPGGGRSDRHQRRQKTTKMLVAVVVVFTVSWLPFHAFQLAVDIDSSVLE 297

Human   300 LKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRC---EQRLDAIHSEVSVTFKAKK 361
            :|::||::|.|||:|||||||||:||||||.|||.:|::.|:|   ...:..:.|..:|..|..:
Zfish   298 MKDFKLLYTAFHIVAMCSTFANPILYGWMNRNYRGSFVAVFKCGRINNGMRRVSSSEAVREKCTR 362

Human   362 NLE 364
            |||
Zfish   363 NLE 365

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
NPY2RNP_000901.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..35
7tmA_NPY2R 51..336 CDD:320521 192/284 (68%)
TM helix 1 52..78 CDD:320521 16/25 (64%)
TM helix 2 85..110 CDD:320521 22/24 (92%)
TM helix 3 123..153 CDD:320521 23/29 (79%)
TM helix 4 164..185 CDD:320521 9/20 (45%)
TM helix 5 216..245 CDD:320521 17/28 (61%)
TM helix 6 261..291 CDD:320521 26/29 (90%)
TM helix 7 304..329 CDD:320521 19/24 (79%)
npy2rXP_021331562.2 None
Blue background indicates that the domain is not in the aligned region.

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