Protein Alignment NPY1R and npy1r

DIOPT Version :10

• Sequence 1: NP_000900.1
• Gene: NPY1R / 4886
• HGNCID: 7956
• Length: 384
• Species: Homo sapiens
• Sequence 2: NP_001095861.1
• Gene: npy1r / 793668
• ZFINID: ZDB-GENE-080221-1
• Length: 380
• Species: Danio rerio
• Alignment Length: 357
• Identity: 215/357 - (60%)
• Similarity: 280/357 - (78%)
• Gaps: 6/357 - (1%)

Human    16 SNFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLALIIIILKQKEMRNVTNILIV 80
            ||.|..|...:|: .|:|:...::...:|:||.||::|||.||||||::|.:|:|:.||||:||.
Zfish    23 SNCSITNLSAIAY-GDECYGSHSLFVIMAVAYSAVVLLGVIGNLALILVIARQRELHNVTNVLIA 86

Human    81 NLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINP 145
            |||.||||:|::||||||:||.|||||||..|||||..|||.|::||||||||||:||||||::|
Zfish    87 NLSVSDLLMAVVCLPFTFIYTFMDHWVFGAVMCKLNSLVQCCSVSVSIFSLVLIAIERHQLILHP 151

Human   146 RGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMTDEPFQ---NVTLDAYKDKYVCFDQFPSDSH 207
            |||||:..||.:||::.|.|||.::.|||::..:||.|.:   :|..:.|:.|.||.:::||...
Zfish   152 RGWRPSLNHACLGISLTWALAVLTATPFLLFSRVTDAPLKQLPSVFQEQYRGKVVCVEEWPSREI 216

Human   208 RLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKRRNNMMDKMRDNKYRSSETKRINIMLLSIVVAF 272
            :|:|||.:|||||..||.||||||.|||.||:||||||:::|:|||||||:|||||||.||||||
Zfish   217 KLTYTTGMLVLQYITPLTFIFICYLKIYTRLQRRNNMMERIRENKYRSSESKRINIMLFSIVVAF 281

Human   273 AVCWLPLTIFNTVFDWNHQIIATCNHNLLFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNF 337
            |||||||.:||.|.||||::...|.|||||.|||||||.|.|:||:||||||:||||||: .|..
Zfish   282 AVCWLPLNVFNAVIDWNHEVAMNCTHNLLFSLCHLTAMCSVCINPVFYGFLNRNFQRDLR-AFRL 345

Human   338 CDFRS-RDDDYETIAMSTMHTDVSKTSLKQAS 368
            |...| |:::|:.:||||::|||||.|||.:|
Zfish   346 CKIVSTRENEYDMVAMSTVNTDVSKMSLKMSS 377

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NPY1R	NP_000900.1	7tmA_NPY1R	41..331	CDD:320517	188/292 (64%)
		TM helix 1	42..68	CDD:320517	15/25 (60%)
		TM helix 2	75..100	CDD:320517	18/24 (75%)
		TM helix 3	113..143	CDD:320517	23/29 (79%)
		TM helix 4	154..175	CDD:320517	10/20 (50%)
		TM helix 5	208..237	CDD:320517	20/28 (71%)
		TM helix 6	256..286	CDD:320517	24/29 (83%)
		TM helix 7	299..324	CDD:320517	19/24 (79%)
npy1r	NP_001095861.1	7tmA_NPY1R	47..340	CDD:320517	188/292 (64%)
		TM helix 1	48..74	CDD:320517	15/25 (60%)
		TM helix 2	81..106	CDD:320517	18/24 (75%)
		TM helix 3	119..149	CDD:320517	23/29 (79%)
		TM helix 4	160..181	CDD:320517	10/20 (50%)
		TM helix 5	217..246	CDD:320517	20/28 (71%)
		TM helix 6	265..295	CDD:320517	24/29 (83%)
		TM helix 7	308..333	CDD:320517	19/24 (79%)