Protein Alignment NPY1R and npr-11

DIOPT Version :9

• Sequence 1: NP_000900.1
• Gene: NPY1R / 4886
• HGNCID: 7956
• Length: 384
• Species: Homo sapiens
• Sequence 2: NP_508234.2
• Gene: npr-11 / 182921
• WormBaseID: WBGene00016110
• Length: 402
• Species: Caenorhabditis elegans
• Alignment Length: 388
• Identity: 110/388 - (28%)
• Similarity: 180/388 - (46%)
• Gaps: 42/388 - (10%)

Human    17 NFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLALIIIILKQKEMRNVTNILIVN 81
            |:..::.|::   |...:.|....:.:..||..:|:.|..||...||:::....||...|..|:|
 Worm    19 NYFFRDDQVI---NGTEYSPKEFGYFITFAYMLIILFGAIGNFLTIIVVILNPAMRTTRNFFILN 80

Human    82 LSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPR 146
            |:.||..|.|:..|.|....|...|.|...:||:...:|..:|.:|.||:..|||:|:.|||.|.
 Worm    81 LALSDFFVCIVTAPTTLYTVLYMFWPFSRTLCKIAGSLQGFNIFLSTFSIASIAVDRYVLIIFPT 145

Human   147 GWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMTD---EPFQNVTLDAYKDKYVCFDQFPSDSHR 208
            ........::....:|||:::..::|.|....:|.   ||..::.|      |:|.:|.......
 Worm   146 KRERQQNLSFCFFIMIWVISLILAVPLLQASDLTPVFVEPSCDLAL------YICHEQNEIWEKM 204

Human   209 L----SYTTLLLVLQYFGPLCFIFICYFKIYIRLK-----RRNNMMDKMRDNKYRSS---ETKRI 261
            :    :||..:|:.||..||..:...|.:|..|:|     |..|:......::.|.|   ..:|.
 Worm   205 IISKGTYTLAVLITQYAFPLFSLVFAYSRIAHRMKLRFANRNQNVTTNTNTSQRRRSVVERQRRT 269

Human   262 NIMLLSIVVAFAVCWLPLT---IFNTVFDWNHQIIATCNHNLLFLLCHLTAMISTCVNPIFYGFL 323
            :::|:.:|..|||.||||.   ||||....|...:.|      |.:||..||.|.|:||:.|.|.
 Worm   270 HLLLVCVVAVFAVAWLPLNVFHIFNTFELVNSFSVTT------FSICHCLAMCSACLNPLIYAFF 328

Human   324 NKNFQRDLQFFFNFCDFRSRD----DDYETIAMSTMHTDVSK----TSLKQASPVAFKKINNN 378
            |.||:.:....|:....||..    .:.|::..| |.|:...    .::..|.|..|:::|.:
 Worm   329 NHNFRIEFMHLFDRVGLRSLRVVIFGEQESLKKS-MRTEFRSRGGCKTVTTAEPATFQRMNES 390

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NPY1R	NP_000900.1	7tm_4	52..>176	CDD:304433	40/123 (33%)
		7tm_1	57..320	CDD:278431	86/280 (31%)
npr-11	NP_508234.2	7tm_4	48..>192	CDD:304433	45/149 (30%)
		7tm_1	56..325	CDD:278431	86/280 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	140	1.000	Domainoid score	I3257
eggNOG	1	0.900	-	-		E33208_3BAX7
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D275052at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24235
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920