Protein Alignment NPY1R and Npy1r

DIOPT Version :10

• Sequence 1: NP_000900.1
• Gene: NPY1R / 4886
• HGNCID: 7956
• Length: 384
• Species: Homo sapiens
• Sequence 2: NP_035064.1
• Gene: Npy1r / 18166
• MGIID: 104963
• Length: 382
• Species: Mus musculus
• Alignment Length: 384
• Identity: 359/384 - (93%)
• Similarity: 375/384 - (97%)
• Gaps: 2/384 - (0%)

Human     1 MNSTLFSQVENHSVHSNFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLALIIII 65
            |||||||:|||||:|.|.|| |:.||||||||||||||:||||||||||||||||||||||||||
Mouse     1 MNSTLFSKVENHSIHYNASE-NSPLLAFENDDCHLPLAVIFTLALAYGAVIILGVSGNLALIIII 64

Human    66 LKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQCVSITVSIFS 130
            |||||||||||||||||||||||||:|||||||||||||||||||.|||||||||||||||||||
Mouse    65 LKQKEMRNVTNILIVNLSFSDLLVAVMCLPFTFVYTLMDHWVFGETMCKLNPFVQCVSITVSIFS 129

Human   131 LVLIAVERHQLIINPRGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMTDEPFQNVTLDAYKDK 195
            ||||||||||||||||||||||||||:||.|||||||||||||:|||::||||||||:|.|:|||
Mouse   130 LVLIAVERHQLIINPRGWRPNNRHAYIGITVIWVLAVASSLPFVIYQILTDEPFQNVSLAAFKDK 194

Human   196 YVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKRRNNMMDKMRDNKYRSSETKR 260
            |||||:||||||||||||||||||||||||||||||||||||||||||||||:||:|||||||||
Mouse   195 YVCFDKFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKRRNNMMDKIRDSKYRSSETKR 259

Human   261 INIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNLLFLLCHLTAMISTCVNPIFYGFLNK 325
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   260 INIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNLLFLLCHLTAMISTCVNPIFYGFLNK 324

Human   326 NFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVSKTSLKQASPVAFKKINNNDDNEKI 384
            ||||||||||||||||||||||||||||||||||||||||||||||||||:.| ||||:
Mouse   325 NFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVSKTSLKQASPVAFKKISMN-DNEKV 382

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NPY1R	NP_000900.1	7tmA_NPY1R	41..331	CDD:320517	276/289 (96%)
		TM helix 1	42..68	CDD:320517	25/25 (100%)
		TM helix 2	75..100	CDD:320517	23/24 (96%)
		TM helix 3	113..143	CDD:320517	29/29 (100%)
		TM helix 4	154..175	CDD:320517	18/20 (90%)
		TM helix 5	208..237	CDD:320517	28/28 (100%)
		TM helix 6	256..286	CDD:320517	29/29 (100%)
		TM helix 7	299..324	CDD:320517	24/24 (100%)
Npy1r	NP_035064.1	7tmA_NPY1R	40..330	CDD:320517	276/289 (96%)
		TM helix 1	41..67	CDD:320517	25/25 (100%)
		TM helix 2	74..99	CDD:320517	23/24 (96%)
		TM helix 3	112..142	CDD:320517	29/29 (100%)
		TM helix 4	153..174	CDD:320517	18/20 (90%)
		TM helix 5	207..236	CDD:320517	28/28 (100%)
		TM helix 6	255..285	CDD:320517	29/29 (100%)
		TM helix 7	298..323	CDD:320517	24/24 (100%)