Protein Alignment NPY1R and npy1r

DIOPT Version :10

• Sequence 1: NP_000900.1
• Gene: NPY1R / 4886
• HGNCID: 7956
• Length: 384
• Species: Homo sapiens
• Sequence 2: XP_017951354.1
• Gene: npy1r / 100494051
• XenbaseID: XB-GENE-22068790
• Length: 366
• Species: Xenopus tropicalis
• Alignment Length: 372
• Identity: 292/372 - (78%)
• Similarity: 326/372 - (87%)
• Gaps: 7/372 - (1%)

Human     1 MNSTLFSQVENHSVHSNFSEKNAQLLAFE-NDDCHLPLAMIFTLALAYGAVIILGVSGNLALIII 64
            ||  |.|..||.||.:|.|..    :.|. ::||.||:.::||||||||||||||:|||||||||
 Frog     1 MN--LSSYFENQSVPNNISGN----ITFPMSEDCALPMPIVFTLALAYGAVIILGLSGNLALIII 59

Human    65 ILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQCVSITVSIF 129
            ||||||||||||||||||||||||..|||||||.:|||||||:|||.|||||.::||||:|||||
 Frog    60 ILKQKEMRNVTNILIVNLSFSDLLATIMCLPFTLIYTLMDHWIFGEVMCKLNEYIQCVSVTVSIF 124

Human   130 SLVLIAVERHQLIINPRGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMTDEPFQNVTLDAYKD 194
            ||||||:|||||||||||||||||||..||.|||.:|:|.|.|.::|.|:|||||:|::||:|..
 Frog   125 SLVLIAIERHQLIINPRGWRPNNRHACFGITVIWGVAMACSSPLMMYSVLTDEPFRNISLDSYIG 189

Human   195 KYVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKRRNNMMDKMRDNKYRSSETK 259
            ||||.:.||.|:.||||||||.:|||.|||||||:||.||::|||||||||||||||||||||||
 Frog   190 KYVCLEDFPEDNFRLSYTTLLFILQYLGPLCFIFVCYTKIFLRLKRRNNMMDKMRDNKYRSSETK 254

Human   260 RINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNLLFLLCHLTAMISTCVNPIFYGFLN 324
            |||||||||||.||:||||..|||.||||||:.|||||||||||:||||||||||||||||||||
 Frog   255 RINIMLLSIVVGFALCWLPFFIFNLVFDWNHEAIATCNHNLLFLICHLTAMISTCVNPIFYGFLN 319

Human   325 KNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVSKTSLKQASPVA 371
            |||||||||||||||||||:|||||||||||||||||||||||||:|
 Frog   320 KNFQRDLQFFFNFCDFRSREDDYETIAMSTMHTDVSKTSLKQASPIA 366

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NPY1R	NP_000900.1	7tmA_NPY1R	41..331	CDD:320517	237/289 (82%)
		TM helix 1	42..68	CDD:320517	24/25 (96%)
		TM helix 2	75..100	CDD:320517	21/24 (88%)
		TM helix 3	113..143	CDD:320517	24/29 (83%)
		TM helix 4	154..175	CDD:320517	11/20 (55%)
		TM helix 5	208..237	CDD:320517	22/28 (79%)
		TM helix 6	256..286	CDD:320517	24/29 (83%)
		TM helix 7	299..324	CDD:320517	23/24 (96%)
npy1r	XP_017951354.1	7tmA_NPY1R	36..326	CDD:320517	237/289 (82%)
		TM helix 1	37..63	CDD:320517	24/25 (96%)
		TM helix 2	70..95	CDD:320517	21/24 (88%)
		TM helix 3	108..138	CDD:320517	24/29 (83%)
		TM helix 4	149..170	CDD:320517	11/20 (55%)
		TM helix 5	203..232	CDD:320517	22/28 (79%)
		TM helix 6	251..281	CDD:320517	24/29 (83%)
		TM helix 7	294..319	CDD:320517	23/24 (96%)