Protein Alignment CG5504 and DNAJA3

DIOPT Version :10

• Sequence 1: NP_995932.1
• Gene: CG5504 / 48844
• FlyBaseID: FBgn0002174
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_005138.3
• Gene: DNAJA3 / 9093
• HGNCID: 11808
• Length: 480
• Species: Homo sapiens
• Alignment Length: 466
• Identity: 217/466 - (46%)
• Similarity: 290/466 - (62%)
• Gaps: 73/466 - (15%)

  Fly    56 HTTRDLLAKDYYATLGVAKNANGKDIKKAYYQLAKKYHPDTNKEDPDAGRKFQEVSEAYEVLSDE 120
            ||:..|..:|||..|||.:||:.|:||||||||||||||||||:||.|..||.:::|||||||||
Human    84 HTSAPLAKEDYYQILGVPRNASQKEIKKAYYQLAKKYHPDTNKDDPKAKEKFSQLAEAYEVLSDE 148

  Fly   121 QKRREYDTYGQTAENIGRQGGGFPGGGAGGFGPEGFSQS--WQFRSSIDPEELFRKIFGEGNFRT 183
            .||::||.||         ..||..|.:|       ||.  |:...::||||||||||||  |.:
Human   149 VKRKQYDAYG---------SAGFDPGASG-------SQHSYWKGGPTVDPEELFRKIFGE--FSS 195

  Fly   184 NSFDDFADSKFGFGQAQEMVMDLTFAQAARGVNKDVNVNVVDQCPKCAGTKCEPGTKPGRCQYCN 248
            :||.||   :..|.|.||..|:|||.|||:||||:..||::|.|.:|.|...|||||...|.||.
Human   196 SSFGDF---QTVFDQPQEYFMELTFNQAAKGVNKEFTVNIMDTCERCNGKGNEPGTKVQHCHYCG 257

  Fly   249 GTGFETVSTGPFVMRSTCRYCQGTRQHIKYPCSECEGKGRTVQRRKVTVPVPAGIENGQTVRMQV 313
            |:|.||::|||||||||||.|.|....|..||..|.|.|:..|:::|.:|||||:|:||||||.|
Human   258 GSGMETINTGPFVMRSTCRRCGGRGSIIISPCVVCRGAGQAKQKKRVMIPVPAGVEDGQTVRMPV 322

  Fly   314 GSKELFVTFRVERSDYFRREGADVHTDAAISLAQAVLGGTVRVQGVYEDQWINVEPGTSSHHKIM 378
            |.:|:|:||||::|..|||:|||:|:|..||:|||:||||.|.||:||...:.:.|||.:..||.
Human   323 GKREIFITFRVQKSPVFRRDGADIHSDLFISIAQALLGGTARAQGLYETINVTIPPGTQTDQKIR 387

  Fly   379 LRGKGLKRVNAHGHGDHYVHVKITVPSAKKLDKKRLALIEAYAELEEDTPGQIHGIANRKDGSKQ 443
            :.|||:.|:|::|:||||:|:||.||  |:|..::.:||.:|||.|.|..|.::|:.....|
Human   388 MGGKGIPRINSYGYGDHYIHIKIRVP--KRLTSRQQSLILSYAEDETDVEGTVNGVTLTSSG--- 447

  Fly   444 ATAGASEEPGAGAAAKASAAAAGSGASKPGPGAEKSEGKDQWTDNEKTKAKEGGGSGSGQGDGGG 508
               |::.:..||:.|:..|                  |:|:
Human   448 ---GSTMDSSAGSKARREA------------------GEDE------------------------ 467

  Fly   509 GGFISKIKSMF 519
            .||:||:|.||
Human   468 EGFLSKLKKMF 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5504	NP_995932.1	djlA	<9..117	CDD:236512	39/60 (65%)
		DnaJ_bact	65..424	CDD:274090	195/360 (54%)
DNAJA3	NP_005138.3	DnaJ_bact	93..429	CDD:274090	193/358 (54%)
		CXXCXGXG motif	236..243		3/6 (50%)
		CXXCXGXG motif	253..260		4/6 (67%)
		CXXCXGXG motif	275..282		4/6 (67%)
		CXXCXGXG motif	289..296		3/6 (50%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	443..471		9/75 (12%)