DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5504 and GFA2

DIOPT Version :9

Sequence 1:	NP_995932.1	Gene:	CG5504 / 48844	FlyBaseID:	FBgn0002174	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_568690.1	Gene:	GFA2 / 834854	AraportID:	AT5G48030	Length:	456	Species:	Arabidopsis thaliana

Alignment Length:	455	Identity:	159/455 - (34%)
Similarity:	238/455 - (52%)	Gaps:	73/455 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 RRCLAAA-----AFSTPRAT---SYRIL-SSAGS---------------------GSTRADAPQV 52
            ||||:::     |....|..   |||.| :|.|:                     |....:....
plant    15 RRCLSSSLIQDLANQKLRGVCIGSYRRLNTSVGNHANVIGDYASKSGHDRKWINFGGFNTNFGST 79

  Fly    53 RRLHTTRD--LLAKDYYATLGVAKNANGKDIKKAYYQLAKKYHPDTNKEDPDAGRKFQEVSEAYE 115
            |..|.|..  :.|||||:.|||:|||...:||||||.||||.|||.||:||:|..||||||:|||
plant    80 RSFHGTGSSFMSAKDYYSVLGVSKNAQEGEIKKAYYGLAKKLHPDMNKDDPEAETKFQEVSKAYE 144

  Fly   116 VLSDEQKRREYDTYGQTAENIGRQGG-----GFPGGGAGGFGPEGFSQSWQFRSSIDPEELFRKI 175
            :|.|::||..||..|..|......||     ||.|||.|||               :|.::|
plant   145 ILKDKEKRDLYDQVGHEAFEQNASGGFPNDQGFGGGGGGGF---------------NPFDIF--- 191

  Fly   176 FGEGNFRTNSFDDFADSKFGFGQAQEMVMDLTFAQAARGVNKDVNVNVVDQCPKCAGTKCEPGTK 240
               |:|..:.|:.:... .| ||..::::||:|.:|.:|.:|.|.......|..|.|....||||
plant   192 ---GSFNGDIFNMYRQD-IG-GQDVKVLLDLSFMEAVQGCSKTVTFQTEMACNTCGGQGVPPGTK 251

  Fly   241 PGRCQYCNGTGFETVSTGPFVMRSTCRYCQGTRQHIKYPCSECEGKGRTVQRRK-VTVPVPAGIE 304
            ..:|:.|||:|..::..|...:::||:.|.|..|.....|..|.| .|.|:.:| |.|.:..|::
plant   252 REKCKACNGSGMTSLRRGMLSIQTTCQKCGGAGQTFSSICKSCRG-ARVVRGQKSVKVTIDPGVD 315

  Fly   305 NGQTVRM-QVGSK--------ELFVTFRVERSDYFRREGADVHTDAAISLAQAVLGGTVRVQGVY 360
            |..|::: :||..        :|:||.:|.....|||||:|:|.||.:|:.||:||||::|..:.
plant   316 NSDTLKVARVGGADPEGDQPGDLYVTLKVREDPVFRREGSDIHVDAVLSVTQAILGGTIQVPTLT 380

  Fly   361 EDQWINVEPGTSSHHKIMLRGKGLKRVNAHGHGDHYVHVKITVPSAKKLDKKRLALIEAYAELEE 425
            .|..:.|.|||...||::||.||::...:...||.|||..:::|:  .:.:::..|:|.:::.|:
plant   381 GDVVVKVRPGTQPGHKVVLRNKGIRARKSTKFGDQYVHFNVSIPA--NITQRQRELLEEFSKAEQ 443

Fly 426 425
plant 444 443

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5504	NP_995932.1	DnaJ	63..437	CDD:223560	143/378 (38%)
		DnaJ	65..127	CDD:278647	40/61 (66%)
		DnaJ_zf	227..287	CDD:199908	21/59 (36%)
		DnaJ_C	288..409	CDD:199909	48/130 (37%)
GFA2	NP_568690.1	DnaJ	90..450	CDD:223560	143/380 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1395
eggNOG	1	0.900	-	-		E2759_KOG0715
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H36170
Inparanoid	1	1.050	254	1.000	Inparanoid score	I1017
OMA	1	1.010	-	-		QHG53632
OrthoDB	1	1.010	-	-		D894595at2759
OrthoFinder	1	1.000	-	-		FOG0001676
OrthoInspector	1	1.000	-	-		otm3217
orthoMCL	1	0.900	-	-		OOG6_100469
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2075
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.740