DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5504 and dnajb4

DIOPT Version :9

Sequence 1:	NP_995932.1	Gene:	CG5504 / 48844	FlyBaseID:	FBgn0002174	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_001003455.1	Gene:	dnajb4 / 445061	ZFINID:	ZDB-GENE-040801-192	Length:	340	Species:	Danio rerio

Alignment Length:	383	Identity:	105/383 - (27%)
Similarity:	161/383 - (42%)	Gaps:	76/383 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 LAKDYYATLGVAKNANGKDIKKAYYQLAKKYHPDTNKEDPDAGRKFQEVSEAYEVLSDEQKRREY 126
            :.||||..||:.|.|:..||||||.:.|.|:|||.||. .:|..||:||:||||||||.:||..|
Zfish     1 MGKDYYKILGITKGASDDDIKKAYRKQALKWHPDKNKA-ANAEEKFKEVAEAYEVLSDPKKREIY 64

  Fly   127 DTYGQTAENIGRQGGGFPGGGAGGFGPEGFSQSWQFRSSIDPEELFRKIFGEGNFRTNSFDDFAD 191
            |.||:.         |..|||....||.| :.::.|..  ||...|...||    ..:.|:.|..
Zfish    65 DQYGEE---------GLKGGGGASDGPGG-NFTYTFHG--DPHATFATFFG----GASPFEVFFG 113

  Fly   192 SKFGFGQAQEMVMDLTFAQAARGVNKDVNVNVVDQCPKCAGTKCE----PGTKPGRCQYCNGTGF 252
            .|.......:|.:|   .....|.....|:|         |...|    .|..|.|.|
Zfish   114 RKVNGRDEDDMEVD---GNDPFGSFTSFNIN---------GFPRERHVGQGGPPRRKQ------- 159

  Fly   253 ETVSTGPFVMR----STCRYCQGTRQHIKYPCSECEGKGRTV--QRRKVTVPVPAGIENGQTVRM 311
                 .|.:..    |......|:.:.:|.........|||:  :.:.:|:.:..|.:.|..:..
Zfish   160 -----DPAIHHELRVSLEEVFHGSTKRMKISRKRLNPDGRTLRTEDKILTIEIKRGWKEGTKITF 219

  Fly   312 -QVGSK-------ELFVTFRVERSDYFRREGADVHTDAAISLAQAVLGGTVRVQGVYEDQWIN-- 366
             :.|.:       ::....:.:...:|||||:|:.....:||.|::.|.:|.|..: :.:..|
Zfish   220 PREGDETPNTIPADIVFVIKDKPHGHFRREGSDIVYPVRVSLRQSLCGCSVTVSTI-DGKTCNMK 283

  Fly   367 ----VEPGTSSHHKIMLRGKGLK-RVNAHGHGDHYVHVKITVP-----SAKKLDKKRL 414
                ::||.    :.::.|:||. ..|....||..|...:..|     :||.:.|:.|
Zfish   284 ITDVIKPGM----RKVIAGQGLPFPKNPEQRGDLIVEFDVNFPESLPTNAKDVLKRHL 337

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5504	NP_995932.1	DnaJ	63..437	CDD:223560	105/382 (27%)
		DnaJ	65..127	CDD:278647	35/61 (57%)
		DnaJ_zf	227..287	CDD:199908	10/67 (15%)
		DnaJ_C	288..409	CDD:199909	31/142 (22%)
dnajb4	NP_001003455.1	DnaJ	1..334	CDD:223560	103/378 (27%)
		DnaJ	4..65	CDD:278647	35/61 (57%)
		DnaJ_C	163..325	CDD:199909	33/166 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910