DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5504 and dnj-27

DIOPT Version :9

Sequence 1:	NP_995932.1	Gene:	CG5504 / 48844	FlyBaseID:	FBgn0002174	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_001040704.1	Gene:	dnj-27 / 173065	WormBaseID:	WBGene00001045	Length:	788	Species:	Caenorhabditis elegans

Alignment Length:	228	Identity:	64/228 - (28%)
Similarity:	105/228 - (46%)	Gaps:	53/228 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 LLAKDYYATLGVAKNANGKDIKKAYYQLAKKYHPDTNKEDPDAGRKFQEVSEAYEVLSDEQKRRE 125
            ::|:|||..|||.::|:.:.|:||:.:||.|.|||.|.:||:|..:|.::::|||||.||..|::
Worm    16 VIAEDYYELLGVERDADDRTIRKAFKKLAIKKHPDRNTDDPNAHDEFVKINKAYEVLKDENLRKK 80

  Fly   126 YDTYGQTAENIGRQGGGFPGGGAGGFGPEGFSQSWQFRSS-----IDPEEL-------FRKIFGE 178
            ||.:|:.....|.|||             ...|||||.:.     .|.:|:       |:::..:
Worm    81 YDQFGEKGLEDGFQGG-------------NNYQSWQFYNDNFGIYDDDQEIVTLNRADFQRMVSD 132

  Fly   179 GN--FRTNSFDDFADSKFGFGQAQEMVMDLTFAQAARGVNKDVNVNVVDQCPKCAGTKCEPGTKP 241
            .|  :..|.:..:.      ....::..  |:.:.||.:...:.|..|:    ||       ..|
Worm   133 SNEIWFINFYSTYC------SHCHQLAP--TWRKFAREIEGTIRVGAVN----CA-------EDP 178

  Fly   242 GRCQYCNGTGFETVSTGP-FVMRSTCRYCQGTR 273
            ..||      .:.|:..| .|...|..:.||.|
Worm   179 QLCQ------SQRVNAYPSLVFYPTGEFYQGHR 205

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5504	NP_995932.1	DnaJ	63..437	CDD:223560	64/226 (28%)
		DnaJ	65..127	CDD:278647	29/61 (48%)
		DnaJ_zf	227..287	CDD:199908	12/48 (25%)
		DnaJ_C	288..409	CDD:199909
dnj-27	NP_001040704.1	DnaJ	18..>150	CDD:223560	47/150 (31%)
		DnaJ	20..82	CDD:278647	29/61 (48%)
		PDI_a_ERdj5_N	116..214	CDD:239301	21/115 (18%)
		Thioredoxin_like	222..>312	CDD:294274
		ER_PDI_fam	438..750	CDD:273457
		PDI_a_ERdj5_C	438..543	CDD:239302
		PDI_a_ERdj5_C	549..664	CDD:239302
		PDI_a_ERdj5_C	670..773	CDD:239302
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910