DRSC/TRiP Functional Genomics Resources

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Protein Alignment NPTX1 and b6

DIOPT Version :10

Sequence 1:NP_002513.2 Gene:NPTX1 / 4884 HGNCID:7952 Length:432 Species:Homo sapiens
Sequence 2:NP_477365.1 Gene:b6 / 31124 FlyBaseID:FBgn0024897 Length:558 Species:Drosophila melanogaster


Alignment Length:214 Identity:51/214 - (23%)
Similarity:80/214 - (37%) Gaps:60/214 - (28%)


- Green bases have known domain annotations that are detailed below.


Human   220 KDNRPGDKFQLTFPLRTNY--MYAKVKK-------------SLPEMYAFTVCMWLKSSATPGVGT 269
            :|..|  |..|.||....|  ....|||             .:||:..||:|.|::.:...|   
  Fly   113 EDEAP--KEPLAFPRSPVYGSDRCSVKKFAFNQDGEVEYGNPMPELDQFTICFWMRFTNHSG--- 172

Human   270 PFSYAVPGQANELVLIEWGNNPMEILI----------------NDKVAKLPFVINDGKWHHICVT 318
                     .:.|:..|.|..|.|:.|                ..::.:|.:.:...:|||:|.:
  Fly   173 ---------DHVLLTYEAGKEPREVQIWVANAQNSSFLSMAIKGQQMYRLNYPLKMRQWHHMCSS 228

Human   319 WTTRDGVWEAYQDGTQGGSG-ENLAPYHPIKPQGVLVLGQEQDTLGGGFDATQAFVGELAHFNIW 382
            |..:.|.|:|:....:.|.| .|....|.|...|.|        ..||...|    ||::|...:
  Fly   229 WNGKTGEWQAWLKAERIGRGFHNSLVGHKIPANGKL--------RSGGSSVT----GEVSHGLHF 281

Human   383 DRKLTPGEVYNLATCSTKA 401
            :..|.  :||.:|..:.||
  Fly   282 EMTLV--QVYRVALSAGKA 298

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
NPTX1NP_002513.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 90..122
GumC <120..>216 CDD:442439
PTX 222..428 CDD:128463 50/212 (24%)
b6NP_477365.1 LamG 134..>264 CDD:473984 31/141 (22%)
Blue background indicates that the domain is not in the aligned region.

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