Protein Alignment Catsup and SLC39A10

DIOPT Version :9

• Sequence 1: NP_524931.1
• Gene: Catsup / 48805
• FlyBaseID: FBgn0002022
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: NP_001120729.1
• Gene: SLC39A10 / 57181
• HGNCID: 20861
• Length: 831
• Species: Homo sapiens
• Alignment Length: 691
• Identity: 157/691 - (22%)
• Similarity: 232/691 - (33%)
• Gaps: 302/691 - (43%)

  Fly    47 SREANENFDPQK-----APRAEHHHHHDHDHDHGHHHHGHDH-DHDHDH---------------- 89
            |.:.|...||:|     :.:::..|.|||:|...|||..|.| ||::.|
Human   146 STKRNHKCDPEKETVEVSVKSDDKHMHDHNHRLRHHHRLHHHLDHNNTHHFHNDSITPSERGEPS 210

  Fly    90 -------------------------------------------GHDHG---HHHHGHDHDHDHDH 108
                                                       .||.|   .|:..|..|..|:.
Human   211 NEPSTETNKTQEQSDVKLPKGKRKKKGRKSNENSEVITPGFPPNHDQGEQYEHNRVHKPDRVHNP 275

  Fly   109 GHHH------HGHDE---------------RHTK--------------AKPDL------------ 126
            ||.|      :|||.               |||:              .:.||
Human   276 GHSHVHLPERNGHDPGRGHQDLDPDNEGELRHTRKREAPHVKNNAIISLRKDLNEDDHHHECLNV 340

  Fly   127 -----------------DMST-------------------------------------------- 130
                             |:.|
Human   341 TQLLKYYGHGANSPISTDLFTYLCPALLYQIDSRLCIEHFDKLLVEDINKDKNLVPEDEANIGAS 405

  Fly   131 IWLHSIGSTLLISAAPFVLLYIIPLDNSEAMKPRLKVLLAFASGGLLGDAFLHLIPHATHPHSHG 195
            .|:..|.|..:||....:.:.::|:.|....|..|..|:|.|.|.:.|||.|||:||:
Human   406 AWICGIISITVISLLSLLGVILVPIINQGCFKFLLTFLVALAVGTMSGDALLHLLPHS------- 463

  Fly   196 EHGHDHGHDHHHHHDGEEHEHGHSHDMSI--------GLWVLGGIIAFLSVEKLVRILKGGHGGH 252
            :.||||.|.|.|.|.   |.|||..:..:        ||..||||.....:|..:|:.|......
Human   464 QGGHDHSHQHAHGHG---HSHGHESNKFLEEYDAVLKGLVALGGIYLLFIIEHCIRMFKHYKQQR 525

  Fly   253 GHSHGAPKP---------------------------KPVPAKKKSSDKED----------SGDGD 280
            |......|.                           ||:.....|...||          .|..:
Human   526 GKQKWFMKQNTEESTIGRKLSDHKLNNTPDSDWLQLKPLAGTDDSVVSEDRLNETELTDLEGQQE 590

  Fly   281 KPAKP-AKIKSKK--PEAEPEG------------------------------------------- 299
            .|.|. ..|:.:|  ..:..:|
Human   591 SPPKNYLCIEEEKIIDHSHSDGLHTIHEHDLHAAAHNHHGENKTVLRKHNHQWHHKHSHHSHGPC 655

  Fly   300 ----EVEISGYLNLA-----ADFAHNFTDGLAIGASYLAGNSIGIVTTITILLHEVPHEIGDFAI 355
                :::.:|..|:|     .|..|||:|||||||::.||.:.||.|:|.:..||:|||:||||:
Human   656 HSGSDLKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVFCHELPHELGDFAV 720

  Fly   356 LIKSGCSRRKAMLLQLVTA----LGALAGTALALLGAGGGDGSAPWVLPFTAGGFIYIATVSVLP 416
            |:|:|.:.::|::..|::|    :|.|.|||:...    .:....|:...|||.|:|:|.|.:||
Human   721 LLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAVGQY----ANNITLWIFAVTAGMFLYVALVDMLP 781

  Fly   417 ELL------EES--TKLKQSLKEIFALLTGVALMIVIAKFE 449
            |:|      ||.  ..:.|.:.:...||.|.|:|:|||.:|
Human   782 EMLHGDGDNEEHGFCPVGQFILQNLGLLFGFAIMLVIALYE 822

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Catsup	NP_524931.1	Zip	129..446	CDD:280666	117/472 (25%)
SLC39A10	NP_001120729.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	126..318		34/171 (20%)
		Zip	404..819	CDD:280666	116/428 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	464..484		11/22 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0428
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D657777at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820