Protein Alignment Catsup and SLC39A5

DIOPT Version :10

• Sequence 1: NP_524931.1
• Gene: Catsup / 48805
• FlyBaseID: FBgn0002022
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: NP_775867.2
• Gene: SLC39A5 / 283375
• HGNCID: 20502
• Length: 540
• Species: Homo sapiens
• Alignment Length: 357
• Identity: 116/357 - (32%)
• Similarity: 166/357 - (46%)
• Gaps: 62/357 - (17%)

  Fly   124 PDLDMSTIWLHSIGSTLLISAAPFVLLYIIPLDNSEAMKPRLKVLLAFASGGLLGDAFLHLIPHA 188
            |..|:.:..|.|..:.||:|....:.|.::.|.....::|.|..|.|.|.|.|.|||.|||:|||
Human   205 PPGDLLSALLQSALAVLLLSLPSPLSLLLLRLLGPRLLRPLLGFLGALAVGTLCGDALLHLLPHA 269

  Fly   189 THPHSHGEHGHDHGHDHHHHHDGEEHEHGHSHDMSIGLWVLGGIIAFLSVEKLVRILKGGHGGHG 253
                ..|.|....|..              ..|:..||.||||:.....:|.::.:|:
Human   270 ----QEGRHAGPGGLP--------------EKDLGPGLSVLGGLFLLFVLENMLGLLR------- 309

  Fly   254 HSHGAPKPKPVPAKKKSSD------KEDSGDGDKPAKPA----------KIKSKKPEAEP----- 297
              |...:|:....|:::.:      :..||...:|.:.|          |.....|...|
Human   310 --HRGLRPRCCRRKRRNLETRNLDPENGSGMALQPLQAAPEPGAQGQREKNSQHPPALAPPGHQG 372

  Fly   298 -----EGEVEISGYLNLAADFAHNFTDGLAIGASYLAGNSIGIVTTITILLHEVPHEIGDFAILI 357
                 :|..:|: ::.|..|..||.||||||||::..|.|.|:.||:.:..||:|||:||||:|:
Human   373 HSHGHQGGTDIT-WMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPHELGDFAMLL 436

  Fly   358 KSGCSRRKAMLLQLVTALGALAGTALALLGAG---GGDGSAPWVLPFTAGGFIYIATVSVLPELL 419
            :||.|.|:.:||.||:  ||| |...|:||.|   |.....|||...|||.|:|:|.|.:||.||
Human   437 QSGLSFRRLLLLSLVS--GAL-GLGGAVLGVGLSLGPVPLTPWVFGVTAGVFLYVALVDMLPALL 498

  Fly   420 E--ESTKLKQSLKEIFALLTGVALMIVIAKFE 449
            .  |.......|.:...||.|..||:.|...|
Human   499 RPPEPLPTPHVLLQGLGLLLGGGLMLAITLLE 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Catsup	NP_524931.1	Zip	129..446	CDD:396884	112/347 (32%)
SLC39A5	NP_775867.2	Zip	248..504	CDD:396884	97/286 (34%)