Protein Alignment Catsup and Slc39a6

DIOPT Version :10

• Sequence 1: NP_524931.1
• Gene: Catsup / 48805
• FlyBaseID: FBgn0002022
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: NP_631882.2
• Gene: Slc39a6 / 106957
• MGIID: 2147279
• Length: 765
• Species: Mus musculus
• Alignment Length: 771
• Identity: 160/771 - (20%)
• Similarity: 240/771 - (31%)
• Gaps: 359/771 - (46%)

  Fly    19 LALVVILGAVLFSLPALCAGQGNPSFKYSRE-ANENFDP----QKAPRAEHHH------------ 66
            |::::||...|:....|...|...:|..:.| .|.|::|    ..|...:.||
Mouse     5 LSVIMILTFALWVTSPLHELQSTAAFSQTTEKINSNWEPGVNVDLAVTMQRHHLQQLFYRYGEND 69

  Fly    67 ------------------------HHDHDHDHGHHHHG-HDHDHDHDHGHDHGHHHHGHDHDHDH 106
                                    ||||:|...|.||. |:|..||:|..||.||   .||:|..
Mouse    70 SLSVEGFRKLLQNIGIDKIKRVHIHHDHEHHADHEHHSDHEHHSDHEHHSDHEHH---SDHEHHS 131

  Fly   107 DHGHHHHGHDERHTKAK--------PDLD------------------------------------ 127
            ||.||.|   ..||.|.        ||||
Mouse   132 DHEHHSH---RSHTVAGKNNRKAFCPDLDSDNSGKNPRTSLGKGSRPAEHMNGRRNIKESASSSE 193

  Fly   128 ---------------MSTI---------------------------------------------- 131
                           :.||
Mouse   194 VTSAVYNAVSEGTRFVETIETPKPGRRTKDVNPSTPPSITEKSRVGRLSRLARKKSNESVSEPRK 258

  Fly   132 ----------------------------------------------------------------- 131
                                                                             
Mouse   259 SFMYSRNTNDNIQECFNTTKLLTSHGMSIQALLNATEFNYLCPAIINQIDARACLIHTASEKKAE 323

  Fly   132 -----------WLHSIGSTLLISAAPFVLL---YIIPLDNSEAMKPRLKVLLAFASGGLLGDAFL 182
                       ||   |..:.||...|:.|   .::||.|....|..|..|:|.|.|.|.|||.|
Mouse   324 IPPKTYSLQIAWL---GGFIAISIISFLSLLGVILVPLMNRVFFKFLLSFLVALAVGTLSGDALL 385

  Fly   183 HLIPHATHPHSHGEHGHDHGHDH----------HHHHDGEEHEHGHSHDMS-IGLWVLGGIIAFL 236
            ||:     ||||..|.|.|.|:.          ..|...:..|.....|.: .||..|||:....
Mouse   386 HLL-----PHSHASHQHSHSHEEPAMEMKRGPLFSHLSAQNIEESSYFDSTWKGLTALGGLYFMF 445

  Fly   237 SVEKLVRILKGGHGGHGHSHGAPK-PKPVPAKKK--------SSDKEDSGDGDKP--------AK 284
            .||.::.::|........:...|: .:.|.:||:        ||::|....|::|        .:
Mouse   446 LVEHVLTLIKQFKDKKKKNQKKPENDEDVESKKQLSKYDSQLSSNEEKVDPGERPESYLRADSQE 510

  Fly   285 PAKIKSKKP--------------------EAEPEG------------------------------ 299
            |:...|::|                    |..|.|
Mouse   511 PSPFDSQQPTMLEEEEVMIAHAHPQEVYNEYVPRGCKNKCHSHFHDTLGQSDDLIHHHHDYHHIL 575

  Fly   300 --------------------EVEISGYLNLA-----ADFAHNFTDGLAIGASYLAGNSIGIVTTI 339
                                |::.:|...||     .|..|||:|||||||::..|.|.|:.|::
Mouse   576 HHHHHQNHHPHSHSQRYSREELKDAGIATLAWMVIMGDGLHNFSDGLAIGAAFTEGLSSGLSTSV 640

  Fly   340 TILLHEVPHEIGDFAILIKSGCSRRKAMLLQLVTALGALAGTALALLGAGGGDGSAPWVLPFTAG 404
            .:..||:|||:||||:|:|:|.:.::|:|...::|:.|..|.|..:......:..:.|:...|||
Mouse   641 AVFCHELPHELGDFAVLLKAGMTVKQAVLYNALSAMLAYLGMATGIFIGHYAENVSMWIFALTAG 705

  Fly   405 GFIYIATVSVLPELLEESTK-----------LKQSLKEIFALLTGVALMIVIAKFE 449
            .|:|:|.|.::||:|.....           |:.:     .:|.|..:|::|:.||
Mouse   706 LFMYVALVDMVPEMLHNDASDHGCSRWGYFFLQNA-----GILLGFGIMLLISIFE 756

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Catsup	NP_524931.1	Zip	129..446	CDD:396884	111/555 (20%)
Slc39a6	NP_631882.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	96..196		30/105 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	209..257		2/47 (4%)
		Zip	333..752	CDD:396884	109/431 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	458..519		11/60 (18%)