DRSC/TRiP Functional Genomics Resources

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Protein Alignment wek and Zfp493

DIOPT Version :9

Sequence 1:NP_001260472.1 Gene:wek / 48785 FlyBaseID:FBgn0001990 Length:470 Species:Drosophila melanogaster
Sequence 2:NP_082678.2 Gene:Zfp493 / 72958 MGIID:1920208 Length:384 Species:Mus musculus


Alignment Length:160 Identity:63/160 - (39%)
Similarity:90/160 - (56%) Gaps:2/160 - (1%)


- Green bases have known domain annotations that are detailed below.


  Fly   271 YPCKICNETFMSFMALRRHKHDMHGGPKKYVCDHCGKGLKTFTSLVEHQLVHTEEKPCICPVCNA 335
            |.||.|.:.|.....|.:|:. :|.|.|.|:|..|||.....::|.:||.:||.|||..|.||:.
Mouse    81 YQCKQCGKAFGWKSLLVQHQR-IHTGEKPYICKECGKAFNYSSTLKQHQRIHTGEKPYKCEVCDK 144

  Fly   336 GFKNKARLRVHSQTH-GEPKFECNVCGKKLQTRAILNKHKYVHTDERRFKCEVCGSGCKNSTALK 399
            .||.....:.|.:.| ||..::|.||||.....:.|.||:.:||.|:.::||.||....|.:.|.
Mouse   145 AFKYSFSFKQHQRIHTGEKPYKCEVCGKAFNCSSYLGKHQRIHTGEKPYRCEECGRAFTNYSGLT 209

  Fly   400 IHLLGHTGLRPYVCKYCGKAFASNTNCRSH 429
            :|...|||::||.|:.|||||::.|....|
Mouse   210 VHRKVHTGVKPYKCEECGKAFSARTTLSKH 239

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
wekNP_001260472.1 zf-AD 11..80 CDD:214871
C2H2 Zn finger 273..294 CDD:275368 6/20 (30%)
C2H2 Zn finger 302..322 CDD:275368 7/19 (37%)
C2H2 Zn finger 330..350 CDD:275368 6/19 (32%)
C2H2 Zn finger 357..377 CDD:275368 8/19 (42%)
C2H2 Zn finger 385..405 CDD:275368 7/19 (37%)
zf-H2C2_2 397..422 CDD:290200 13/24 (54%)
C2H2 Zn finger 413..429 CDD:275368 7/15 (47%)
Zfp493NP_082678.2 KRAB 5..65 CDD:214630
KRAB 5..44 CDD:279668
C2H2 Zn finger 83..103 CDD:275368 6/20 (30%)
zf-H2C2_2 96..120 CDD:290200 10/24 (42%)
C2H2 Zn finger 111..131 CDD:275368 7/19 (37%)
zf-H2C2_2 124..148 CDD:290200 12/23 (52%)
C2H2 Zn finger 139..159 CDD:275368 6/19 (32%)
zf-H2C2_2 151..176 CDD:290200 9/24 (38%)
C2H2 Zn finger 167..187 CDD:275368 8/19 (42%)
zf-H2C2_2 179..204 CDD:290200 10/24 (42%)
COG5048 <191..327 CDD:227381 20/49 (41%)
C2H2 Zn finger 195..215 CDD:275368 7/19 (37%)
zf-H2C2_2 208..231 CDD:290200 12/22 (55%)
C2H2 Zn finger 223..243 CDD:275368 8/17 (47%)
zf-H2C2_2 236..259 CDD:290200 1/4 (25%)
C2H2 Zn finger 251..271 CDD:275368
C2H2 Zn finger 279..299 CDD:275368
zf-H2C2_2 292..316 CDD:290200
C2H2 Zn finger 307..327 CDD:275368
C2H2 Zn finger 335..355 CDD:275368
zf-H2C2_2 347..372 CDD:290200
C2H2 Zn finger 363..383 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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