DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment wek and pad

DIOPT Version :9

Sequence 1:NP_001260472.1 Gene:wek / 48785 FlyBaseID:FBgn0001990 Length:470 Species:Drosophila melanogaster
Sequence 2:NP_650534.2 Gene:pad / 41981 FlyBaseID:FBgn0038418 Length:924 Species:Drosophila melanogaster


Alignment Length:314 Identity:77/314 - (24%)
Similarity:118/314 - (37%) Gaps:68/314 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   135 TSPSPDFEAQ-------------TVRTRANLKQCNSD------PKVLAS-----PT---ASIPEV 172
            |.|.|..:.|             |...:|.:::.:|:      ||..||     ||   |.:|.:
  Fly   540 TKPQPQVKQQQTAGLSASGAPTATSANQAAMQRLSSNTTITKVPKQPASLPAPAPTSNPAKLPML 604

  Fly   173 ETKR---SR-RQQFAAKRNSKVYTATESDDEEAILDEDEAVSPPPLKRKRGRPKGSGKQKNVDDS 233
            ..:.   || ..|.|.|..||..|.:.:...:.|     .||.|.|.:.:..|..:..:|.|   
  Fly   605 NKQNITISRISMQTAPKAQSKPSTTSPTPASQPI-----PVSVPALSQAQPPPLAAQHKKIV--- 661

  Fly   234 DNVTSREPDDN-----AKSKQDDKTSELSMSPH---------GSQSSNFVDYPCKICNETFMSFM 284
                 |:|.:|     .|.|......::..||.         ||::.......|..|...|....
  Fly   662 -----RKPPENQDTSGQKVKAARPPQQILPSPQQEGQNATHSGSEAPTTSGLICPTCKREFKKKE 721

  Fly   285 ALRRHKHDMHGGPKKYVC--DHCGKGLKTFTSLVEHQLVHTEEKPCICPVCNAGFKNKARL---- 343
            .|.:|. .:|.|.:.:.|  :.|.|.......|..|.:.|:.:|...|.||...|..|..|    
  Fly   722 HLTQHV-KLHAGLRPFKCSEEGCDKTFSRKEHLSRHLVSHSGQKMYTCEVCKKPFSRKDNLNKHR 785

  Fly   344 RVHSQTHGEPKFECNVCGKKLQTRAILNKHKYVHTDERRFKCEVCGSGCKNSTA 397
            |:|:||..|..:.|:||.|...|:....||:.:|   ::.:.|....|...|.|
  Fly   786 RIHTQTSTETLYCCDVCNKNFATKLHYEKHREMH---KKIRPESAAPGATASPA 836

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
wekNP_001260472.1 zf-AD 11..80 CDD:214871
C2H2 Zn finger 273..294 CDD:275368 5/20 (25%)
C2H2 Zn finger 302..322 CDD:275368 5/21 (24%)
C2H2 Zn finger 330..350 CDD:275368 9/23 (39%)
C2H2 Zn finger 357..377 CDD:275368 7/19 (37%)
C2H2 Zn finger 385..405 CDD:275368 4/13 (31%)
zf-H2C2_2 397..422 CDD:290200 1/1 (100%)
C2H2 Zn finger 413..429 CDD:275368
padNP_650534.2 zf-AD 16..87 CDD:214871
C2H2 Zn finger 710..730 CDD:275368 5/20 (25%)
zf-C2H2 736..760 CDD:278523 5/23 (22%)
C2H2 Zn finger 738..760 CDD:275368 5/21 (24%)
zf-H2C2_2 752..777 CDD:290200 8/24 (33%)
zf-C2H2 766..788 CDD:278523 7/21 (33%)
C2H2 Zn finger 768..788 CDD:275368 7/19 (37%)
zf-H2C2_2 780..808 CDD:290200 10/27 (37%)
C2H2 Zn finger 799..819 CDD:275368 7/19 (37%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR24377
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
11.100

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