Protein Alignment wek and CG6254

DIOPT Version :10

• Sequence 1: NP_524930.1
• Gene: wek / 48785
• FlyBaseID: FBgn0001990
• Length: 470
• Species: Drosophila melanogaster
• Sequence 2: NP_649983.2
• Gene: CG6254 / 41244
• FlyBaseID: FBgn0037794
• Length: 634
• Species: Drosophila melanogaster
• Alignment Length: 589
• Identity: 167/589 - (28%)
• Similarity: 255/589 - (43%)
• Gaps: 165/589 - (28%)

  Fly     8 WIYWCRLCARD-----DVVYKVRERD---DDLVRIISKCFDVEMTLEEPELGSMLCEECYSVIGQ 64
            |..|||||:::     :|.::..:::   ..:...|.|.|.|::..|: ||.:.||.||::::..
  Fly    18 WHQWCRLCSKEHPTNQNVFFREAKQNSWASTMAMTIGKYFWVDIKRED-ELSNFLCSECFTLMDC 81

  Fly    65 LITFSDSVSKVQAIFELLRHSEPQDSQDLDALRLEYGL--------------------------- 102
            ||.||:.|.|||.:|..|:..:..:..|.:.:|.:.|:
  Fly    82 LIEFSERVRKVQILFSKLQLLQSNNLMDYEKIREDCGVATDGWKHIMLGAVDESLPQNDEVFISE 146

  Fly   103 --PPAC---------------------------KQDL-EFLDIDDTEDRCSLVEELTISDHSTSP 137
              |..|                           |||. :..|:.:.|.:.|.|||..:.:.....
  Fly   147 EQPIVCQTETSSKMKSEILMIPNFLVEKQCLQEKQDFPKEEDVIEEEMQISGVEEEILEEDVEED 211

  Fly   138 SPDFEAQTVRTRANL--KQCNSDPKVLASPTAS---IPEVETKRSRR---------QQFAAKRNS 188
            ..:.|.:||....:.  ::..:..:.|.:..|:   :.|||.....|         :...:..|.
  Fly   212 LAEEEVETVEEEIDTVGEEVEAVEEELETQDATDCLVEEVEHMTEDRYIEESQIIEESQVSDFNM 276

  Fly   189 KVY------------------TATESDDE-------EAILDEDEAVSPPP-------LKRKRGRP 221
            :.|                  .:.||:::       |.:.||::.:|..|       .|:...:|
  Fly   277 ETYEIVQHNPQKEPVETKDTVESIESNEDTQEDISREHVTDEEDEISEVPAMYKCNICKKPYKKP 341

  Fly   222 KGSGKQKNVDDSDNVTSREPDD---------------------------NAKSKQDDKTSELSMS 259
            |  ..::::::..|..:   ||                           .||.|.|      :..
  Fly   342 K--AYKRHMEEVHNTVA---DDLPQLECNQCKLCFPTVAQLHAHHRTHVRAKPKTD------NCC 395

  Fly   260 PHGSQSSNFVDYPCKICNETFMSFMALRRHKHDMHGGPKKYVCDHCGKGLKTFTSLVEHQLVHTE 324
            ||              |.:.|.:...|:||...:|...|.||||.|||.....|.|.:|:||||:
  Fly   396 PH--------------CEKRFTTSGTLKRHIEGIHNQIKPYVCDLCGKSFNYITGLKDHKLVHTD 446

  Fly   325 EKPCICPVCNAGFKNKARLRVHSQTHGEPKFECNVCGKKLQTRAILNKHKYVHTDERRFKCEVCG 389
            |.|..||||..||||.|||::|..||....:||.|||.||:||...||||.||:|.|:|||||||
  Fly   447 ECPFECPVCKRGFKNNARLKIHLDTHSAEIYECTVCGLKLKTRRTFNKHKLVHSDTRQFKCEVCG 511

  Fly   390 SGCKNSTALKIHLLGHTGLRPYVCKYCGKAFASNTNCRSHKWKKHP-ELASKEDETESSRVPVPT 453
            |..|.|..||.||:.|||:|||.|.:||:.||:.:||||||.:.|| |||.:|....:....:|.
  Fly   512 SAFKRSKTLKAHLILHTGIRPYKCNFCGRDFANGSNCRSHKRQAHPKELAEEEARGVTRSTLLPM 576

  Fly   454 LEEL 457
            |:||
  Fly   577 LDEL 580

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wek	NP_524930.1	zf-AD	11..80	CDD:462262	25/76 (33%)
		SFP1	<226..346	CDD:227516	43/146 (29%)
		C2H2 Zn finger	273..294	CDD:275368	5/20 (25%)
		C2H2 Zn finger	302..322	CDD:275368	9/19 (47%)
		SFP1	<320..401	CDD:227516	49/80 (61%)
		C2H2 Zn finger	330..350	CDD:275368	12/19 (63%)
		C2H2 Zn finger	357..377	CDD:275368	12/19 (63%)
		SFP1	<379..434	CDD:227516	33/54 (61%)
		C2H2 Zn finger	385..405	CDD:275368	12/19 (63%)
		C2H2 Zn finger	413..429	CDD:275368	8/15 (53%)
CG6254	NP_649983.2	zf-AD	21..99	CDD:462262	26/78 (33%)
		COG5048	<353..554	CDD:227381	94/223 (42%)
		C2H2 Zn finger	364..384	CDD:275368	0/19 (0%)
		C2H2 Zn finger	395..416	CDD:275368	7/34 (21%)
		C2H2 Zn finger	424..444	CDD:275368	9/19 (47%)
		C2H2 Zn finger	452..472	CDD:275368	12/19 (63%)
		C2H2 Zn finger	479..499	CDD:275368	12/19 (63%)
		C2H2 Zn finger	507..527	CDD:275368	12/19 (63%)
		C2H2 Zn finger	535..553	CDD:275368	10/17 (59%)