DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wek and CG9932

DIOPT Version :9

Sequence 1:	NP_001260472.1	Gene:	wek / 48785	FlyBaseID:	FBgn0001990	Length:	470	Species:	Drosophila melanogaster
Sequence 2:	NP_609599.1	Gene:	CG9932 / 34701	FlyBaseID:	FBgn0262160	Length:	2171	Species:	Drosophila melanogaster

Alignment Length:	425	Identity:	80/425 - (18%)
Similarity:	127/425 - (29%)	Gaps:	132/425 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 ELGSMLCE---ECYSVIGQLITFSDSVSKVQAIFELLRHSEPQDSQDLDALRLEYGLPP------ 104
            :.||.|.|   |.:. :.||:......:.|.|:...::..:.|..|.:.....|.|||.
  Fly    54 QAGSSLLERHVERFR-LQQLLQQQRQAAAVVAVVNSVQQQQQQQPQQVGMDAKEEGLPQCKIKRN 117

  Fly   105 -ACKQDLEFL-----------DIDDTE---DRC-----------SLVEELTISDHSTSPSPDFEA 143
             :|.....|.           |:...:   ::|           .||..:.:....|...|....
  Fly   118 YSCNHCAYFTQNPRYHLTHLRDVHGEKIVINKCKLCLYASRHFQKLVRHMKMVHGCTDGIPSGHG 182

  Fly   144 QT-----VRTRANLKQCNSDPKVLA--SPTASIPEVET-----------------------KRSR 178
            |.     :...|..::......|:.  |.|.::|:|.|                       :|.|
  Fly   183 QARGKRGMSREARKRRLEESVGVMGGQSLTVTVPDVPTLEQVKRELLLQEEKLQRDIQAFNQRQR 247

  Fly   179 RQQFAAKRNSKVYTATESDDEE-AILDEDEAVSP--PPLKRKRGRPKGSGKQKNVDDSDNVTSRE 240
            .:|...::......||.:.:.: .:|.:.|..||  ||                 ..|....|..
  Fly   248 EEQQREQQRELELVATSAYERQMQVLRDYERQSPAEPP-----------------TPSPTSGSAT 295

  Fly   241 PDDNAKSKQDDKTSELSMSPHGSQSSNFVDYPCKICNETFMSFMALRRHKHDMHGGPKKYVCDHC 305
            |..|.:..|:....                  |..|..|.:....||.|:...||..|.:.||.|
  Fly   296 PPSNGEEPQNRLLK------------------CSACEFTTLYRTQLRAHELAEHGKTKFFRCDKC 342

  Fly   306 GKGLKTFTSLVEHQLVHTEEKPCICPVCNAGFKNKARLRVHSQTHGEPKFECNVCGKKLQTRAIL 370
                    |.|.|                    .|||...|.:.|..|..:|..|..:...:..|
  Fly   343 --------SYVTH--------------------IKARFSKHVKYHSMPMIKCVTCDFRTPYKWNL 379

  Fly   371 NKHKYVHTDERRFKCEVCGSGCKNSTALKIHLLGH 405
            ::|...|.....|||..|........:|.:|.:.|
  Fly   380 DRHMKNHGGAGAFKCAACDFTADIKQSLTVHEMNH 414

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wek	NP_001260472.1	zf-AD	11..80	CDD:214871	9/33 (27%)
		C2H2 Zn finger	273..294	CDD:275368	6/20 (30%)
		C2H2 Zn finger	302..322	CDD:275368	6/19 (32%)
		C2H2 Zn finger	330..350	CDD:275368	4/19 (21%)
		C2H2 Zn finger	357..377	CDD:275368	4/19 (21%)
		C2H2 Zn finger	385..405	CDD:275368	4/19 (21%)
		zf-H2C2_2	397..422	CDD:290200	3/9 (33%)
		C2H2 Zn finger	413..429	CDD:275368
CG9932	NP_609599.1	C2H2 Zn finger	339..359	CDD:275368	10/47 (21%)
		C2H2 Zn finger	366..386	CDD:275368	4/19 (21%)
		C2H2 Zn finger	394..414	CDD:275368	4/19 (21%)
		C2H2 Zn finger	816..836	CDD:275370
		C2H2 Zn finger	844..862	CDD:275370
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444642
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930