DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wek and Zfp93

DIOPT Version :9

Sequence 1:	NP_001260472.1	Gene:	wek / 48785	FlyBaseID:	FBgn0001990	Length:	470	Species:	Drosophila melanogaster
Sequence 2:	NP_001100016.1	Gene:	Zfp93 / 296399	RGDID:	1309760	Length:	427	Species:	Rattus norvegicus

Alignment Length:	268	Identity:	70/268 - (26%)
Similarity:	118/268 - (44%)	Gaps:	30/268 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   171 EVETKRSRRQQFAAKRNSKVYTATESDDEEAILDEDEAVSPPPLKRKRGRPKGSGKQKNVDDSDN 235
            :.:.:..|.|:...:||.....|..:..|.|...|:.|..|      .|.|        .:|||
  Rat     6 QAKPQHLRSQEPQPERNEPGGVAPRTAGEPASALENAAQKP------AGLP--------AEDSD- 55

  Fly   236 VTSREPDDNA--KSKQDDKTSELSMSPHGSQSSNFVDYP-CKICNETFMSFMALRRHKHDMHGGP 297
              :::|...|  .|:..::|:.|     |.::.|.. || |..  :|......|.||.. :|.|.
  Rat    56 --AQQPAAVALPTSEAKERTATL-----GERTFNCC-YPGCHF--KTVHGMKDLDRHLR-IHTGD 109

  Fly   298 KKYVCDHCGKGLKTFTSLVEHQLVHTEEKPCICPVCNAGFKNKARLRVHSQTHGEPK-FECNVCG 361
            |.:.|:.|.|......:|..|...||..||..|.:|:....:.:.|:.|.:.|.:.: ::|.:|.
  Rat   110 KPHKCEFCDKCFSRKDNLTMHMRCHTSVKPHKCHLCDYAAVDSSSLKKHLRIHSDERPYKCQMCP 174

  Fly   362 KKLQTRAILNKHKYVHTDERRFKCEVCGSGCKNSTALKIHLLGHTGLRPYVCKYCGKAFASNTNC 426
            ...:..:.|..|...||.:..|:|.:|.:..|.|:.||.|::.|:|.:|:.|::|........|.
  Rat   175 YASRNSSQLTVHLRSHTGDTPFQCWLCSAKFKISSDLKRHMIVHSGEKPFKCEFCDVRCTMKANL 239

  Fly   427 RSHKWKKH 434
            :||...||
  Rat   240 KSHIRIKH 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wek	NP_001260472.1	zf-AD	11..80	CDD:214871
		C2H2 Zn finger	273..294	CDD:275368	5/20 (25%)
		C2H2 Zn finger	302..322	CDD:275368	5/19 (26%)
		C2H2 Zn finger	330..350	CDD:275368	4/19 (21%)
		C2H2 Zn finger	357..377	CDD:275368	4/19 (21%)
		C2H2 Zn finger	385..405	CDD:275368	7/19 (37%)
		zf-H2C2_2	397..422	CDD:290200	8/24 (33%)
		C2H2 Zn finger	413..429	CDD:275368	3/15 (20%)
Zfp93	NP_001100016.1	COG5048	<96..227	CDD:227381	37/131 (28%)
		zf-H2C2_2	98..123	CDD:290200	9/25 (36%)
		C2H2 Zn finger	114..134	CDD:275368	5/19 (26%)
		C2H2 Zn finger	142..162	CDD:275368	4/19 (21%)
		C2H2 Zn finger	170..190	CDD:275368	4/19 (21%)
		C2H2 Zn finger	198..218	CDD:275368	7/19 (37%)
		zf-H2C2_2	210..234	CDD:290200	8/23 (35%)
		C2H2 Zn finger	226..245	CDD:275368	5/18 (28%)
		C2H2 Zn finger	279..299	CDD:275368
		C2H2 Zn finger	307..328	CDD:275368
		C2H2 Zn finger	364..384	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166338038
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930